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Ligand 15-hydroperoxy-prostaglandin E2

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.3.99.3

15-hydroperoxy-prostaglandin E2 + GSH = prostaglandin E2 + GSSG

652399

-

Product in Enzyme-catalyzed Reactions (2 results)

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EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.3.99.3

prostaglandin G2 = 15-hydroperoxy-prostaglandin E2

3129, 0

-

5.3.99.3

prostaglandin G2 + GSH = 15-hydroperoxy-prostaglandine E2 + GSSG

652399

-

5.3.99.3

2 entries

Enzyme Kinetic Parameters

References & Links

Literature References (2)

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BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

3129

838703

Prostaglandin endoperoxide E isomerase from bovine vesicular gland microsomes, a glutathione-requiring enzyme

1977

Ogino, N.; Miyamoto, T.; Yamamoto, S.; Hayaishi, O.

J. Biol. Chem.

252

890-895

652399

12672824

Human microsomal prostaglandin E synthase-1: purification, functional characterization, and projection structure determination

2003

Thoren, S.; Weinander, R.; Saha, S.; Jegerschoeld, C.; Pettersson, P.L.; Samuelsson, B.; Hebert, H.; Hamberg, M.; Morgenstern, R.; Jakobsson, P.J.

J. Biol. Chem.

278

22199-22209

Links to other databases for 15-hydroperoxy-prostaglandin E2

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ChEBI

PubChem

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