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Ligand (R)-allantoin

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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Show Natural Product (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.1.99.3

(S)-allantoin = (R)-allantoin

0

-

Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.1.99.3

(R)-allantoin = (S)-allantoin

715939, 747111

-

Product in Enzyme-catalyzed Reactions (2 results)

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Show Product (2 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

5.1.99.3

(S)(+)-Allantoin = (R)(-)-Allantoin

2444, 2445

-

5.1.99.3

(S)-allantoin = (R)-allantoin

0

-

5.1.99.3

2 entries

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (3 results)

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Show Turnover Number (3 entries)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

5.1.99.3

43

-

mutant E78D, pH 7.6, temperature not specified in the publication

747111

5.1.99.3

57

-

wild-type, pH 7.6, temperature not specified in the publication

747111

5.1.99.3

238

-

in 10 mM NaCl and 10 mM HEPES, pH 7.5, at 25°C

715939

5.1.99.3

3 entries

K_M Value (3 results)

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Show KM Value (3 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

5.1.99.3

0.4

-

in 10 mM NaCl and 10 mM HEPES, pH 7.5, at 25°C

715939

5.1.99.3

1.1

-

wild-type, pH 7.6, temperature not specified in the publication

747111

5.1.99.3

2.3

-

mutant E78D, pH 7.6, temperature not specified in the publication

747111

5.1.99.3

3 entries

References & Links

Literature References (4)

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Show Reference (4 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

2444

568622

Enzymic racemization of allantoin

1978

Okumura, I.; Yamamoto, T.

J. Biochem.

84

891-895

2445

237557

Allantoin racemase: a new enzyme from Pseudomonas species

1975

Van der Drift, L.; Vogels, G.D.; van der Drift, C.

Biochim. Biophys. Acta

391

240-248

715939

21616082

Characterization of the structure and function of Klebsiella pneumoniae allantoin racemase

2011

French, J.B.; Neau, D.B.; Ealick, S.E.

J. Mol. Biol.

410

447-460

747111

27797489

The structure and function of a microbial allantoin racemase reveal the origin and conservation of a catalytic mechanism

2016

Cendron, L.; Ramazzina, I.; Puggioni, V.; Maccacaro, E.; Liuzzi, A.; Secchi, A.; Zanotti, G.; Percudani, R.

Biochemistry

55

6421-6432

Links to other databases for (R)-allantoin

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Show Links (1 entry)

ChEBI

PubChem