Ligand 2-hydroxy-5-methyl-1-naphthoate

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Basic Ligand Information

Molecular Structure

C₁₂H₁₀O₃

2-hydroxy-5-methyl-1-naphthoate

KKMAZNUSFFWQQY-UHFFFAOYSA-N

Synonyms:

NCTT-956

KEGG

Biosynthesis of enediyne antibiotics, Biosynthesis of secondary metabolites

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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1.14.15.31

2-hydroxy-5-methyl-1-naphthoate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = 2,7-dihydroxy-5-methyl-1-naphthoate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O

727548

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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2.3.1.237

acetyl-CoA + 5 malonyl-CoA + 2 NADPH + 2 H+ = 2-hydroxy-5-methyl-1-naphthoate + 6 CoA + 5 CO2 + 3 H2O + 2 NADP+

Substrate in Enzyme-catalyzed Reactions (2 results)

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1.14.15.31

2-hydroxy-5-methyl-1-naphthoate + 2 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + O2 = 2,7-dihydroxy-5-methyl-1-naphthoate + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O

727548

6.2.1.43

ATP + 2-hydroxy-5-methyl-1-naphthoate + CoA = AMP + diphosphate + 2-hydroxy-5-methyl-1-naphthoyl-CoA

725189