Ligand indole-3-acetamide

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Basic Ligand Information

Molecular Structure
Picture of indole-3-acetamide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H10N2O
indole-3-acetamide
ZOAMBXDOGPRZLP-UHFFFAOYSA-N
Synonyms:
(indol-3-yl)acetamide, (indole-3-yl)acetamide, 3-indolacetamide, 3-Indoleacetamide, 3-indolylacetamide, indol-3-acetamide


Show all pahtways known for Show all BRENDA pathways known for indole-3-acetamide

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
indole-3-acetamide + H2O = indole-3-acetic acid + NH3
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 indole-3-acetonitrile + 3 H2O = indole-3-acetamide + indole-3-acetic acid + NH3
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-indoleacetamide + O2 = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2 indole-3-acetonitrile + 3 H2O = indole-3-acetamide + indole-3-acetic acid + NH3
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
allosteric effector, binds to the alpha-subunit, slightly activating effect on the enzyme complex, stabilization of the alpha-aminoacrylate Schiff base by perturbing the equilibrium of the catalytic intermediates formed at the beta-active site
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Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
allosteric effector, binds to the alpha-subunit, inhibitory on the alpha-reaction
-

3D Structure of Enzyme-Ligand-Complex (PDB) (15 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (6 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

Ki Value (7 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.45
-
pH 7.8, 20°C

References & Links

Links to other databases for indole-3-acetamide

ChEBI
PubChem
ChEBI
PubChem