Ligand aclacinomycin T

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Basic Ligand Information

Molecular Structure
Picture of aclacinomycin T (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C30H35NO10
aclacinomycin T
LJZPVWKMAYDYAS-QKKPTTNWSA-N
Synonyms:
2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxo-4-[[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy]-1-naphthacenecarboxylic acid methyl ester, 4-O-(beta-L-rhodosaminyl)aklavinone, methyl (1R,2R,4S)-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-4-{[2,3,6-trideoxy-3-(dimethylamino)-alpha-L-lyxo-hexopyranosyl]oxy}-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate, rhodosaminyl-aklavinone, rhodosaminyl aklavinone


Show all pahtways known for Show all BRENDA pathways known for aclacinomycin T

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dTDP-2-deoxy-beta-L-fucose + aclacinomycin T = dTDP + aclacinomycin S
show the reaction diagram
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aclacinomycin T + H2O = 15-demethylaclacinomycin T + methanol
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
S-adenosyl-L-methionine + aclacinomycin T = S-adenosyl-L-homocysteine + triglycosylated aclacinomycin A
show the reaction diagram
aclacinomycin T + H2O = 15-demethylaclacinomycin T + methanol
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (3 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0155
-
pH 7.5, 37°C

References & Links

Links to other databases for aclacinomycin T

ChEBI
PubChem
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PubChem