Ligand (S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate

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Basic Ligand Information

Molecular Structure
Picture of (S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H8O4
(S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate
YHXHKYRQLYQUIH-ZETCQYMHSA-N
Synonyms:
(2S)-hydroxy(4-hydroxyphenyl)acetic acid, (S)-4-hydroxymandelate, (S)-4-ydroxymandelate, 4-hydroxy-(S)-mandelate, 4-Hydroxy-L-mandelate, p-Hydroxy-L-mandelate


Show all pahtways known for Show all BRENDA pathways known for (S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2-hydroxy-2-(4-hydroxyphenyl)acetate + O2 = 4-hydroxybenzaldehyde + CO2 + H2O2
show the reaction diagram
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(2S)-hydroxy(4-hydroxyphenyl)acetic acid + acceptor = (4-hydroxyphenyl)(oxo)acetic acid + reduced acceptor
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(S)-2-hydroxy-2-phenylacetate + tetrahydropteridine = (S)-4-hydroxymandelate + dihydropteridine + H2O
show the reaction diagram
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3D Structure of Enzyme-Ligand-Complex (PDB) (15 results)

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
3.5
-
at pH 7.5 and 28°C

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
64
-
at pH 7.5 and 28°C
73.5
-
pH 8.0, 30°C

References & Links

Links to other databases for (S)-2-Hydroxy-2-(4-hydroxyphenyl)acetate

ChEBI
PubChem
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PubChem