Ligand 2-hydroxyestrone

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 2-hydroxyestrone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C18H22O3
2-hydroxyestrone
QTTNOSKSLATGQB-UHFFFAOYSA-N
Synonyms:
Catecholestrone
Pathway Source
Pathways

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3'-phosphoadenylylsulfate + 2-hydroxyestrone = adenosine 3',5'-bisphosphate + estrone 2-sulfate
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
reversible inhibition of recombinant soluble enzyme in dose dependent manner, IC50 in low micromolar range
-

Enzyme Kinetic Parameters

KM Value (11 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0012
-
-

References & Links

Links to other databases for 2-hydroxyestrone

ChEBI
PubChem
-
PubChem