Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Please wait a moment until the data is sorted. This message will disappear when the data is sorted.
Purification and characterization of hydrolytic haloalkane dehalogenase from Xanthobacter autotrophicus GJ10
1985
Keuning, S.; Janssen, D.B.; Witholt, B.
J. Bacteriol.
163
635-639
Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase
1993
Verschueren, K.H.G.; Seljee, F.; Rozeboom, H.J.; Kalk, K.H.; Dijkstra, B.W.
Nature
363
693-698
-
Kinetic characterization and X-ray structure of a mutant of haloalkane dehalogenase with higher catalytic activity and modified substrate range
1996
Schanstra, J.P.; Ridder, I.S.; Heimeriks, G.J.; Rink, R.; Poelarends, G.J.; Kalk, K.H.; Dijkstra, B.W.; Janssen, D.B.
Biochemistry
35
13185-13195
Purification and characterization of a haloalkane dehalogenase of a new substrate class from a gamma-hexachlorocyclohexane-degrading bacterium, Sphingomonas paucimobilis UT26
1997
Nagata, Y.; Miyauchi, K.; Damborsky, J.; Manova, K.; Ansorgova, A.; Takagi, M.
Appl. Environ. Microbiol.
63
3707-3710
Histidine 289 is essential for hydrolysis of the alkyl-enzyme intermediate of haloalkane dehalogenase
1995
Pries, F.; Kingma, J.; Krooshof, G.H.; Jeronimus-Stratingh, C.M.; Bruins, A.; Janssen, D.B.
J. Biol. Chem.
270
10405-10411
Kinetic analysis and X-ray structure of haloalkane dehalogenase with a modified halide-binding site
1998
Krooshof, G.H.; Ridder, I.S.; Tepper, A.W.J.; Vos, G.J.; Rozeboom, H.J.; Kalk, K.H.; Dijkstra, B.W.; Janssen, D.B.
Biochemistry
37
15013-15023
Haloalkane dehalogenases: steady-state kinetics and halide inhibition
1999
Schindler, J.F.; Naranjo, P.A.; Honaberger, D.A.; Chang, C.H.; Brainard, J.R.; Vanderberg, L.A.; Unkefer, C.J.
Biochemistry
38
5772-5778
The importance of reactant positioning in enzyme catalysis: a hybrid quantum mechanics /molecular mechanics study of a haloalkane dehalogenase
2000
Lau, E.Y.; Kahn, K.; Bash, P.A.; Bruice, T.C.
Proc. Natl. Acad. Sci. USA
97
9937-9942
Characterization of the haloacid dehalogenase from Xanthobacter autotrophicus GJ10 and sequencing of the dhlB gene
1991
Van der Ploeg, J.; Van Hall, G.; Janssen, D.B.
J. Bacteriol.
173
7925-7933
Dichloromethane dehalogenase of Hyphomicrobium sp. strain DM2
1985
Kohler-Staub, D.; Leisinger, T.
J. Bacteriol.
162
676-681
-
Dichloromethane dehalogenase from Hyphomicobium DM2
1990
Leisinger, T.; Kohler-Staub, D.
Methods Enzymol.
188
355-361
Comparative binding energy analysis of the substrate specificity of haloalkane dehalogenase from Xanthobacter autotrophicus GJ10
2001
Kmunicek, J.; Luengo, S.; Gago, F.; Ortiz, A.R.; Wade, R.C.; Damborsky, J.
Biochemistry
40
8905-8917
Exploring the structure and activity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26: evidence for product- and water-mediated inhibition
2002
Oakley, A.J.; Prokop, Z.; Bohac, M.; Kmunicek, J.; Jedlicka, T.; Monincova, M.; Kuta-Smatanova, I.; Nagata, Y.; Damborsky, J.; Wilce, M.C.J.
Biochemistry
41
4847-4855
Dynamics of an enzymatic substitution reaction in haloalkane dehalogenase
2004
Nam, K.; Prat-Resina, X.; Garcia-Viloca, M.; Devi-Kesavan, L.S.; Gao, J.
J. Am. Chem. Soc.
126
1369-1376
Modification of acivity and specificity of haloalkane dehalogenase from Sphingomonas paucimobilis UT26, by engineering of its entrance tunnel
2003
Chaloupkova, R.; Sykorova, J.; Prokop, Z.; Jesenska, A.; Moninkova, M.; Pavlova, M.; Tsuda, M.; Nagata, Y.; Damborsky, J.
J. Biol. Chem.
278
52622-52628
Metabolism of mono- and dihalogenated C1 and C2 compounds by Xanthobacter autotrophicus growing on 1,2-dichloroethane
2006
Torz, M.; Wietzes, P.; Beschkov, V.; Janssen, D.B.
Biodegradation
18
145-157
Haloalkane and haloacid dehalogenase from aerobic bacterial isolates indigenous to contaminated sites in Africa demonstrate diverse substrate specificities
2004
Olaniran, A.O.; Pillay, D.; Pillay, B.
Chemosphere
55
27-33
Dynamic and electrostatic effects in enzymatic processes. An analysis of the nucleophilic substitution reaction in haloalkane dehalogenase
2005
Soriano, A.; Silla, E.; Tunon, I.; Ruiz-Lopez, M.F.
J. Am. Chem. Soc.
127
1946-1957
The identification of catalytic pentad in the haloalkane dehalogenase DhmA from Mycobacterium avium N85: Reaction mechanism and molecular evolution
2006
Pavlova, M.; Klva?a, M.; Jesenska, A.; Prokop, Z.; Kone?na, H.; Sato, T.; Tsuda, M.; Nagata, Y.; Damborsky, J.
J. Struct. Biol.
157
384-392
Exploring the binding sites of the haloalkane dehalogenase DhlA from Xanthobacter autotrophicus GJ10
2007
Silberstein, M.; Damborsky, J.; Vajda, S.
Biochemistry
46
9239-9249
X-ray crystal structure of Mycobacterium tuberculosis haloalkane dehalogenase Rv2579
2008
Mazumdar, P.A.; Hulecki, J.C.; Cherney, M.M.; Garen, C.R.; James, M.N.
Biochim. Biophys. Acta
1784
351-362
Stepwise dissection and visualization of the catalytic mechanism of haloalkane dehalogenase LinB using molecular dynamics simulations and computer graphics
2007
Negri, A.; Marco, E.; Damborsky, J.; Gago, F.
J. Mol. Graph. Model.
26
643-651
1,2-dichloroethane in haloalkane dehalogenase protein and in water solvent: a case study of confinement effect on structural and dynamical properties
2009
Murugan, N.A.; Agren, H.
J. Phys. Chem. B
113
3257-3263
Engineering a catabolic pathway in plants for the degradation of 1,2-dichloroethane
2008
Mena-Benitez, G.L.; Gandia-Herrero, F.; Graham, S.; Larson, T.R.; McQueen-Mason, S.J.; French, C.E.; Rylott, E.L.; Bruce, N.C.
Plant Physiol.
147
1192-1198
Substrate specificity of haloalkane dehalogenases
2011
Koudelakova, T.; Chovancova, E.; Brezovsky, J.; Monincova, M.; Fortova, A.; Jarkovsky, J.; Damborsky, J.
Biochem. J.
435
345-354
Biochemical and biophysical characterisation of haloalkane dehalogenases DmrA and DmrB in Mycobacterium strain JS60 and their role in growth on haloalkanes
2015
Fung, H.; Gadd, M.; Drury, T.; Cheung, S.; Guss, J.; Coleman, N.; Matthews, J.
Mol. Microbiol.
97
439-453
Biochemical characterization of a haloalkane dehalogenase DadB from Alcanivorax dieselolei B-5
2014
Li, A.; Shao, Z.
PLoS ONE
9
e89144
Cloning, expression, purification and three-dimensional structure prediction of haloalkane dehalogenase from a recently isolated Ancylobacter aquaticus strain UV5
2014
Kumar, A.; Pillay, B.; Olaniran, A.O.
Protein Expr. Purif.
99
10-17
Metagenome-derived haloalkane dehalogenases with novel catalytic properties
2017
Kotik, M.; Vanacek, P.; Kunka, A.; Prokop, Z.; Damborsky, J.
Appl. Microbiol. Biotechnol.
101
6385-6397
Conformational changes allow processing of bulky substrates by a haloalkane dehalogenase with a small and buried active site
2018
Kokkonen, P.; Bednar, D.; Dockalova, V.; Prokop, Z.; Damborsky, J.
J. Biol. Chem.
293
11505-11512
Biochemical and biophysical characterisation of haloalkane dehalogenases DmrA and DmrB in Mycobacterium strain JS60 and their role in growth on haloalkanes
2015
Fung, H.; Gadd, M.; Drury, T.; Cheung, S.; Guss, J.; Coleman, N.; Matthews, J.
Mol. Microbiol.
97
439-453
close all tables 
open all tables
top
