Ligand guanidinophenol

benzoyl-4-guanidinophenyl ester + H2O = benzoyl + 4-guanidinophenol

benzoyl-D-Ala-4-guanidinophenyl ester + H2O = benzoyl-D-Ala + 4-guanidinophenol

benzoyl-D-Leu-4-guanidinophenyl ester + H2O = benzoyl-D-Leu + 4-guanidinophenol

benzoyl-D-Phe-4-guanidinophenyl ester + H2O = benzoyl-D-Phe + 4-guanidinophenol

benzoyl-Gly-4-guanidinophenyl ester + H2O = benzoyl-Gly + 4-guanidinophenol

benzoyl-L-Ala-4-guanidinophenyl ester + H2O = benzoyl-L-Ala + 4-guanidinophenol

Nalpha-Boc-D-Ala-(p-guanidino)phenyl ester + L-Ala-4-nitroanilide = Nalpha-Boc-D-Ala-L-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

Nalpha-Boc-D-Leu-(p-guanidino)phenyl ester + L-Ala-4-nitroanilide = Nalpha-Boc-D-Leu-L-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

Nalpha-Boc-D-Phe-(p-guanidino)phenyl ester + L-Ala-4-nitroanilide = Nalpha-Boc-D-Phe-L-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

Nalpha-Boc-Gly-(p-guanidino)phenyl ester + L-Ala-4-nitroanilide = Nalpha-Boc-Gly-L-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

Nalpha-Boc-L-Ala-(p-guanidino)phenyl ester + L-Ala-4-nitroanilide = Nalpha-Boc-L-Ala-L-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

Nalpha-Boc-L-Leu-(p-guanidino)phenyl ester + L-Ala-4-nitroanilide = Nalpha-Boc-L-Leu-L-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

Nalpha-Boc-L-Phe-(p-guanidino)phenyl ester + L-Ala-4-nitroanilide = Nalpha-Boc-L-Phe-L-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

Nbeta-Boc-beta-Ala-(p-guanidino)phenyl ester + beta-Ala-4-nitroanilide = Nbeta-Boc-beta-Ala-beta-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

Nbeta-Boc-beta-Ala-(p-guanidino)phenyl ester + L-Ala-4-nitroanilide = Nbeta-Boc-beta-Ala-L-Ala-4-nitroanilide + 1-(4-hydroxyphenyl)guanidine

CBZ-beta-Ala 4-guanidinophenyl ester + L-Phe-NH2 + H2O = CBZ-beta-Ala-L-Phe-NH2 + CBZ-beta-Ala + 4-guanidinophenol

CBZ-D-Ala 4-guanidinophenyl ester + L-Phe-NH2 + H2O = CBZ-D-Ala-L-Phe-NH2 + CBZ-D-Ala + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + D-Phe-NH2 + H2O = CBZ-Gly-D-Phe-NH2 + CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + H2O = CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + L-Ala 4-nitroanilide + H2O = CBZ-Gly-L-Ala 4-nitroanilide + CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + L-Ala-NH2 + H2O = CBZ-Gly-L-Ala-NH2 + CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + L-Phe tert-butyl ester + H2O = CBZ-Gly-L-Phe tert-butyl ester + CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + L-Phe-NH2 + H2O = CBZ-Gly-L-Phe-NH2 + CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + L-Pro 4-nitroanilide + H2O = CBZ-Gly-L-Pro 4-nitroanilide + CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + L-Ser 4-nitroanilide + H2O = CBZ-Gly-L-Ser 4-nitroanilide + CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + L-Tyr 4-nitroanilide + H2O = CBZ-Gly-L-Tyr 4-nitroanilide + CBZ-Gly + 4-guanidinophenol

CBZ-Gly 4-guanidinophenyl ester + L-Tyr-NH2 + H2O = CBZ-Gly-L-Tyr-NH2 + CBZ-Gly + 4-guanidinophenol

CBZ-L-Ala 4-guanidinophenyl ester + L-Phe-NH2 + H2O = CBZ-L-Ala-L-Phe-NH2 + CBZ-L-Ala + 4-guanidinophenol

CBZ-L-Arg 4-guanidinophenyl ester + L-Phe-NH2 + H2O = CBZ-L-Arg-L-Phe-NH2 + CBZ-L-Arg + 4-guanidinophenol

CBZ-L-Asn 4-guanidinophenyl ester + L-Phe-NH2 + H2O = L-Asn-L-Phe-NH2 + CBZ-L-Asn + 4-guanidinophenol

CBZ-L-Glu 4-guanidinophenyl ester + L-Phe-NH2 + H2O = CBZ-Glu-L-Phe-NH2 + CBZ-L-Glu + 4-guanidinophenol

CBZ-L-Ile 4-guanidinophenyl ester + L-Phe-NH2 + H2O = CBZ-L-Ile-L-Phe-NH2 + CBZ-L-Ile + 4-guanidinophenol

CBZ-L-Thr 4-guanidinophenyl ester + L-Phe-NH2 + H2O = CBZ-L-Thr-L-Phe-NH2 + CBZ-L-Thr + 4-guanidinophenol

benzoyl-Phe 4-guanidinephenyl ester + 2-amino-4-methyl-pentan-1-ol = 4-guanidinephenol + benzoyl-Phe-2-amino-4-methyl-pentan-1-ol

benzoyl-Phe 4-guanidinephenyl ester + 3-amino-propane-1,2-diol = 4-guanidinephenol + benzoyl-Phe-3-amino-propane-1,2-diol

benzoyl-Phe 4-guanidinephenyl ester + 3-amino-propanol = 4-guanidinephenol + benzoyl-Phe-3-amino-propanol

benzoyl-Phe 4-guanidinephenyl ester + 5-amino-pentanol = 4-guanidinephenol + benzoyl-Phe-5-amino-pentanol

benzoyl-Phe 4-guanidinephenyl ester + cycloheptylamine = 4-guanidinephenol + benzoyl-Phe-cycloheptylamide

benzoyl-Phe 4-guanidinephenyl ester + pentylamine = 4-guanidinephenol + benzoyl-Phe-pentylamide

Show Reference (2 entries)

benzoyl-Phe 4-guanidinephenyl ester + propylamine = 4-guanidinephenol + benzoyl-Phe-propylamide

Enzyme Kinetic Parameters

References & Links

Literature References (2)

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BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

10848965

Trypsin-specific acyl-4-guanidinophenyl esters for alpha-chymotrypsin-catalysed reactions computational predictions, hydrolyses, and peptide bond formation

2000

Gunther, R.; Thust, S.; Hofmann, H.J.; Bordusa, F.

Eur. J. Biochem.

267

3496-3501