Ligand 4-nitrophenyl acetate

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Basic Ligand Information

Molecular Structure
Picture of 4-nitrophenyl acetate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H7NO4
4-nitrophenyl acetate
QAUUDNIGJSLPSX-UHFFFAOYSA-N
Synonyms:
4-nitrophenol acetate, nitrophenyl acetate, p-nitrophenyl-acetate, p-nitrophenyl acetate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (125 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
p-nitrophenyl acetate + H2O = p-nitrophenol + acetate
show the reaction diagram
-
p-nitrophenyl acetate + CoA + NAD+ = p-nitrophenol + acetyl-CoA + NADH
show the reaction diagram
-
acetyl-CoA + 4-nitrophenyl acetate = ?
show the reaction diagram
-
p-nitrophenyl acetate + alanine ethylester = N-acetylalanine ethylester + p-nitrophenol
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
p-nitrophenyl acetate + H2O = p-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = ?
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
p-nitrophenyl acetate + H2O = p-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
p-nitrophenyl acetate + H2O = nitrophenolate + acetate
show the reaction diagram
-
p-nitrophenyl acetate + H2O = p-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
p-nitrophenyl acetate + H2O = p-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate + H2O = 4-nitrophenol + acetate
show the reaction diagram
-
4-nitrophenyl acetate = ?
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
an inhibition of CaE activity by 4-nitrophenyl acetate is observed at substrate concentration higher than 5 mM
-
increasing concentrations of the ester inhibit casein hydrolysis
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (195 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.26
-
-
7.8
-
-
6.8
-
at pH 7.5 and 55°C
64
-
37°C, pH 7.5
1.07
-
-
3160
-
pH 7.5, 40°C
18.5
-
in 50 mM HEPES-K (pH 7.5) buffer, at 37°C
0.042
-
-
0.46
-
37°C, pH 7.0
170
-
-
1070
-
at pH 7.0 and 30°C

KM Value (297 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0043
-
-
1.4
-
-
4.35
-
-
0.97
-
at pH 7.5 and 55°C
0.054
-
37°C, pH 7.5
0.2
-
-
0.392
-
pH 8.0, 30°C
1.308
-
50°C, pH 8.0
0.29
-
in 50 mM HEPES-K (pH 7.5) buffer, at 37°C
0.63
-
-
21
-
-
16.7
-
37°C, pH 7.0
0.031
-
-
0.018
-
25°C, pH 8
0.036
-
at pH 7.0 and 30°C
0.07
-
pH 7.0, 30°C
0.3
-
-

References & Links

Links to other databases for 4-nitrophenyl acetate

ChEBI
PubChem
ChEBI
PubChem