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Ligand zeinoxanthin

Basic Ligand Information

Molecular Structure

Show all BRENDA pathways known for zeinoxanthin

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Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Natural Substrate (1 entry)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.14.158

zeinoxanthin + [reduced NADPH-hemoprotein reductase] + O2 = lutein + [oxidized NADPH-hemoprotein reductase] + H2O

728502, 744606, 746186

-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

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Show Natural Product (2 entries)

EC NUMBER

PROVEN IN VIVO REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.15.24

alpha-carotene + reduced acceptor + H+ + O2 = zeinoxanthin + acceptor + H2O

0

-

1.14.15.24

beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 = zeinoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O

0

-

1.14.15.24

2 entries

Substrate in Enzyme-catalyzed Reactions (1 result)

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Show Substrate (1 entry)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.14.158

zeinoxanthin + [reduced NADPH-hemoprotein reductase] + O2 = lutein + [oxidized NADPH-hemoprotein reductase] + H2O

716454, 716526, 716732, 716737, 728502, 744606, 749030, 746186

-

Product in Enzyme-catalyzed Reactions (3 results)

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Show Product (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.15.24

alpha-carotene + 4 reduced ferredoxin [iron-sulfur] cluster + 2 H+ + 2 O2 = zeinoxanthin + 4 oxidized ferredoxin [iron-sulfur] cluster + 2 H2O

0

-

1.14.15.24

alpha-carotene + reduced acceptor + H+ + O2 = zeinoxanthin + acceptor + H2O

0

-

1.14.15.24

beta-carotene + 2 reduced ferredoxin [iron-sulfur] cluster + H+ + O2 = zeinoxanthin + 2 oxidized ferredoxin [iron-sulfur] cluster + H2O

0

-

1.14.15.24

3 entries

Enzyme Kinetic Parameters

References & Links

Literature References (8)

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Show Reference (8 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

716454

19939422

Over-expression of Arabidopsis thaliana carotenoid hydroxylases individually and in combination with a beta-carotene ketolase provides insight into in vivo functions

2010

Kim, J.; Cheng, K.; Craft, N.; Hamberger, B.; Douglas, C.

Phytochemistry

71

168-178

716526

8837513

Arabidopsis carotenoid mutants demonstrate that lutein is not essential for photosynthesis in higher plants

1996

Pogson, B.; McDonald, K.A.; Truong, M.; Britton, G.; DellaPenna, D.

Plant Cell

8

1627-1639

716732

14709673

The Arabidopsis LUT1 locus encodes a member of the cytochrome p450 family that is required for carotenoid epsilon-ring hydroxylation activity

2004

Tian, L.; Musetti, V.; Kim, J.; Magallanes-Lundback, M.; DellaPenna, D.

Proc. Natl. Acad. Sci. USA

101

402-407

716737

16492736

Defining the primary route for lutein synthesis in plants: the role of Arabidopsis carotenoid beta-ring hydroxylase CYP97A3

2006

Kim, J.; DellaPenna, D.

Proc. Natl. Acad. Sci. USA

103

3474-3479

728502

23796723

Overexpression of a tomato carotenoid epsilon-hydroxylase gene alleviates sensitivity to chilling stress in transgenic tobacco

2013

Zhou, B.; Deng, Y.S.; Kong, F.Y.; Li, B.; Meng, Q.W.

Plant Physiol. Biochem.

70

235-245

744606

27358074

Expression and functional analysis of Citrus carotene hydroxylases unravelling the xanthophyll biosynthesis in citrus fruits

2016

Ma, G.; Zhang, L.; Yungyuen, W.; Tsukamoto, I.; Iijima, N.; Oikawa, M.; Yamawaki, K.; Yahata, M.; Kato, M.

BMC Plant Biol.

16

148

746186

26030746

Cloning and functional characterization of the maize (Zea mays L.) carotenoid epsilon hydroxylase gene

2015

Chang, S.; Berman, J.; Sheng, Y.; Wang, Y.; Capell, T.; Shi, L.; Ni, X.; Sandmann, G.; Christou, P.; Zhu, C.

PLoS ONE

10

e0128758

749030

25467956

Biosynthetic routes of hydroxylated carotenoids (xanthophylls) in Marchantia polymorpha, and production of novel and rare xanthophylls through pathway engineering in Escherichia coli

2015

Takemura, M.; Maoka, T.; Misawa, N.

Planta

241

699-710

Links to other databases for zeinoxanthin

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Show Links (1 entry)

ChEBI

PubChem