Ligand (E,Z)-indolyl-3-acetaldoxime

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Basic Ligand Information

Molecular Structure
Picture of (E,Z)-indolyl-3-acetaldoxime (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C10H10N2O
(E,Z)-indolyl-3-acetaldoxime
ZLIGRGHTISHYNH-WUXMJOGZSA-N
Synonyms:
(E)-indol-3-ylacetaldoxime, (E/Z)-indole-3-acetaldoxime, (indol-3-yl)acetaldehyde oxime, 3-indoleacetaldoxime, indole-3-acetaldehyde oxime, indole-3-acetaldoxime

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
indole-3-acetaldoxime + [reduced NADPH-hemoprotein reductase] + O2 = 1-aci-nitro-2-indolyl-ethane + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
indole-3-acetaldoxime + O2 + glutathione + [reduced NADPH-hemoprotein reductase] = 1-aci-nitro-2-indolyl-ethane + H2O + [oxidized NADPH-hemoprotein reductase]
show the reaction diagram
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indole-3-acetaldoxime + [reduced NADPH-hemoprotein reductase] + O2 = hydroxy(1H-indol-3-yl)acetonitrile + [oxidized NADPH-hemoprotein reductase] + 2 H2O
show the reaction diagram
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(E/Z)-indole-3-acetaldoxime = indole-3-acetonitrile + H2O
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-tryptophan + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = (E)-indol-3-ylacetaldoxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.028
-
pH 7.6, 30°C
10
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in 25 mM Tris-HCl buffer pH 7.5, at 23°C

KM Value (7 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0082
-
pH 7.6, 30°C
0.003
-
pH 7.6, 28°C

References & Links

Links to other databases for (E,Z)-indolyl-3-acetaldoxime

ChEBI
PubChem
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PubChem