Ligand 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine

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Basic Ligand Information

Molecular Structure
Picture of 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H13N5O
6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine
ARHXUJTYUBUXBB-UHFFFAOYSA-N
Synonyms:
(6RS)-6,7-dimethyltetrahydropterin, 2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydro-pteridine, 2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine, 2-amino-4-hydroxy-6,7-dimethyl-tetrahydropteridine, 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine, 2-amino-6,7-dimethyl-4-hydroxy-5,6,7,8-tetrahydropteridine, 2-amino-6,7-dimethyl-5,6,7,8-tetrahydropteridin-4-ol, 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydropteridine, 6,7-dimethyl-5,6,7,8-tetrahydropterine

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-phenylalanine + 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine = ?
show the reaction diagram
-
L-tryptophan + 2-amino-4-hydroxy-6,7-dimethyl-5,6,7,8-tetrahydropteridine + O2 = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-amino-4-hydroxy-6,7-dimethyl-quinonoid-dihydropteridine + NAD(P)H = 2-amino-4-hydroxy-6,7-dimethyltetrahydropteridine + NAD(P)+
show the reaction diagram
-

Enzyme Cofactor/Cosubstrate (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
94.2% of the activity with 6R-tetrahydrobiopterin
-

Activator in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
can replace ascorbate
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
above 0.000025 mM, slight inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
510
-
-

KM Value (22 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.054
-
-

References & Links

Links to other databases for 6,7-dimethyl-2-amino-4-hydroxy-5,6,7,8-tetrahydopteridine

ChEBI
PubChem
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PubChem