Ligand Isoxanthopterin

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Basic Ligand Information

Molecular Structure
Picture of Isoxanthopterin (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H5N5O2
Isoxanthopterin
GLKCOBIIZKYKFN-UHFFFAOYSA-N
Synonyms:
2-Amino-4,7-dihydroxypteridine, 2-aminopteridine-4,7(1H,8H)-dione

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-amino-4-hydroxy-pterin + NAD+ + H2O = isoxanthopterin + NADH
show the reaction diagram
-
2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + ?
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-aminopteridine-4,7(1H,8H)-dione + H2O = 7-hydroxypteridine-2,4(1H,3H)-dione + NH3
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
2-amino-4-hydroxypteridine + O2 = 2-amino-4,7-dihydroxypteridine + ?
show the reaction diagram
-
pterin + H2O + O2 = isoxanthopterin + H2O2
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.05 mM: very slight
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.05
-
pH 8.5, 30°C

KM Value (1 result)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.008
-
pH 8.5, 30°C

References & Links

Links to other databases for Isoxanthopterin

ChEBI
PubChem
ChEBI
PubChem