Ligand vorinostat

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Basic Ligand Information

Molecular Structure
Picture of vorinostat (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C14H20N2O3
vorinostat
WAEXFXRVDQXREF-UHFFFAOYSA-N
Synonyms:
N~1~-hydroxy-N~8~-phenyloctanediamide, SAHA, suberoyl anilide hydroxamic acid, suberoylanilide hydroxamic acid, suberoylanilide hydroxyamic acid

Show all pahtways known for Show all pathways known for vorinostat

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-glucuronate + vorinostat = UDP + vorinostat beta-D-glucuronoside
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (108 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
strong inhibition
-
i.e. Zolinza
-

3D Structure of Enzyme-Ligand-Complex (PDB) (8 results)

Enzyme Kinetic Parameters

Ki Value (4 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

IC50 Value (23 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE

References & Links

Links to other databases for vorinostat

ChEBI
PubChem
ChEBI
PubChem