Ligand thio-NADH

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Basic Ligand Information

Molecular Structure
Picture of thio-NADH (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C21H29N7O13P2S
thio-NADH
MUNXPFPYDLZAKA-UHFFFAOYSA-N
Synonyms:
beta-thionicotinamide adenine dinucleotide, reduced form, reduced thionicotinamide adenine dinucleotide, Thionicotinamide-NADH, thionicotinamideNADH

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
thio-NADH + H+ + ubiquinone + 2 Na+/in = thio-NAD+ + ubiquinol + 2 Na+/out
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
thio-NADH + NADP+ = thio-NAD+ + NADPH
show the reaction diagram
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des-myo-inositol mycothione + thio-NADH = ?
show the reaction diagram
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lipoamide + thio-NADH = dihydrolipoamide + thio-NAD+
show the reaction diagram
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thio-NADH + NADP+ = thio-NAD+ + NADPH
show the reaction diagram
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thio-NADH + H+ + ubiquinone + 2 Na+/in = thio-NAD+ + ubiquinol + 2 Na+/out
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (19 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
formaldehyde + glutathione + thio-NAD+ = S-formylglutathione + thio-NADH
show the reaction diagram
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D-glucose 6-phosphate + thionicotinamide-NAD+ = 6-phospho-D-glucono-1,5-lactone + thionicotinamide-NADH + H+
show the reaction diagram
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(S)-malate + thionicotinamide-NAD+ = oxaloacetate + thionicotinamide-NADH + H+
show the reaction diagram
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D-glucose 6-phosphate + thio-NAD+ = 6-phospho-D-glucono-1,5-lactone + thio-NADH + H+
show the reaction diagram
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cholic acid + thio-NAD+ = 7alpha,12alpha-dihydroxy-5beta-cholan-3-one-24-oic acid + thio-NADH
show the reaction diagram
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(2R,3S)-3-isopropylmalate + thionicotinamide NAD+ = 2-oxoisohexanoate + thionicotinamideNADH + CO2
show the reaction diagram
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D-malate + thio-NAD+ = pyruvate + CO2 + thio-NADH + H+
show the reaction diagram
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formate + thio-NAD+ = CO2 + thio-NADH
show the reaction diagram
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D-glyceraldehyde 3-phosphate + thio-NAD+ + phosphate = 3-phospho-D-glyceroyl phosphate + thio-NADH
show the reaction diagram
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acetaldehyde + thio-NAD+ + H2O = acetate + thio-NADH + H+
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D-malate + thio-NAD+ = pyruvate + CO2 + thio-NADH
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L-Leu + H2O + thionicotinamide-NAD+ = 4-methyl-2-oxopentanoate + NH3 + thionicotinamide-NADH
show the reaction diagram
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thio-NAD+ + NADH = thio-NADH + NAD+
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.09
-
des-myo-inositol mycothione as second substrate
0.11
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References & Links

Links to other databases for thio-NADH

ChEBI
PubChem
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PubChem