Ligand Phenyllactate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of Phenyllactate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H10O3
Phenyllactate
XUGWUUDOWNZAGW-VDAHYXPESA-N
Synonyms:
(R,S)-3-phenyllactate, 2-hydroxy-3-phenylpropanoate, 2-hydroxy-3-phenylpropionate, 3-Phenyllactate, 3-phenyllactic acid, beta-phenyllactate, DL-3-phenyllactate, DL-beta-Phenyllactate, DL-phenyllactate, DL-phenyllactic acid, phenyllactic acid

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phenylpyruvate + NADH = phenyllactate + NAD+
show the reaction diagram
-
-
phenylpyruvate + NADH = phenyllactate + NAD+
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phenyllactate + NAD+ = phenylpyruvate + NADH
show the reaction diagram
-
3-phenyllactate + NAD+ = pyruvate + NADH + H+
show the reaction diagram
-
phenyllactate + ferricytochrome c = phenylpyruvate + ferrocytochrome c
show the reaction diagram
-
beta-phenyllactate + O2 = ?
show the reaction diagram
-
3-phenyllactic acid + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (21 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phenylpyruvate + NADH = phenyllactate + NAD+
show the reaction diagram
-
-
phenylpyruvate + NADH = phenyllactate + NAD+
show the reaction diagram
-
-
phenylpyruvate + NADH + H+ = 3-phenyllactate + NAD+
show the reaction diagram
-
-
phenylpyruvate + NAD(P)H = phenyllactate + NAD(P)+
show the reaction diagram
-
phenylpyruvate + NADH = phenyllactate + NAD+
show the reaction diagram
-
hippuryl-DL-phenyllactate + H2O = hippuric acid + DL-phenyllactate
show the reaction diagram
-
-
hippurylphenyllactic acid + H2O = hippuric acid + phenyllactic acid
show the reaction diagram
-
-
prephenyl lactate = phenyllactate + CO2 + H2O
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
short chain oxidase: 10% inhibition of glycolate oxidation, 81% inhibition of L-2-hydroxisocaproate oxidation at 10 mM
-
competitive inhibition
-
partial inhibition, maximal at 0.08 mM
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.21
-
-
0.64
-
pH 8.0, 30°C
0.1
-
pH 7.0 and 7.5

Ki Value (2 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.5
-
competitive
1
-
mixed inhibition

References & Links

Links to other databases for Phenyllactate

ChEBI
PubChem
-
PubChem