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Characterization of nucleoside-diphosphate kinase from Pseudomonas aeruginosa: Complex formation with succinyl-CoA synthetase
1994
Kavanaugh-Black, A.; Connolly, D.M.; Chugani, S.A.; Chakrabarty, A.M.
Proc. Natl. Acad. Sci. USA
91
5883-5887
Purification and properties of asparagine synthetase from rat liver
1978
Hongo, S.; Matsumoto, T.; Sato, T.
Biochim. Biophys. Acta
522
258-266
Purification and properties of the catalytic subunit of the branched-chain alpha-keto acid dehydrogenase phosphatase from bovine kidney mitochondria
1987
Damuni, Z.; Reed, L.J.
J. Biol. Chem.
262
5129-5132
Inosine nucleosidase from Azotobacter vinelandii. Purification and properties
1978
Yoshino, M.; Tsukada, T.; Tsushima, K.
Arch. Microbiol.
119
59-64
T4 phage deoxyribonucleotide-synthesizing enzyme complex. Further studies on enzyme composition and regulation
1983
Allen, J.R.; Lasser, G.W.; Goldman, D.A.; Booth, J.W.; Mathews, C.K.
J. Biol. Chem.
258
5746-5753
-
Interaction of calcium and magnesium in activating and inhibiting the nucleoside triphosphatase of sarcoplasmic reticulum vesicles
1975
Vianna, A.L.
Biochim. Biophys. Acta
410
389-406
Two nucleic acid-dependent nucleoside triphosphate phosphohydrolases from vaccinia virus. Nucleotide substrate and polynucleotide cofactor specificities
1974
Paoletti, E.; Moos, B.
J. Biol. Chem.
249
3281-3286
Some properties of a Ca2+- and (or) Mg2+-requiring nucleoside di- and tri-phosphatase(s) associated with the membranes of rat pancreatic zymogen granules
1978
Harper, F.; Lamy, F.; Calvert, R.
Can. J. Biochem.
56
565-567
Characterisation of Ca2+ or Mg2+-dependent nucleoside triphosphatase from rat mesenteric small arteries
1991
Plesner L.; Juul B.; Scriver E.; Aalkjaer C.
Biochim. Biophys. Acta
1067
191-200
Characterization of the nucleoside triphosphatase activity of poliovirus protein 2C reveals a mechanism by which guanidine inhibits poliovirus replication
1999
Pfister T.; Wimmer E.
J. Biol. Chem.
274
6992-7001
Characterization of the vaccinia virus RNA 5¦-triphosphatase and nucleoside triphosphate phosphohydrolase activities
1996
Myette J.R.; Niles E.G.
J. Biol. Chem.
271
11945-11952
Nucleotidases in plants: V. Purification and properties of an enzyme hydrolysing flavin adenine dinucleotide at acid pH value from Phaseolus radiatus
1971
Ravindranath, S.D.; Rao, N.A.
Indian J. Biochem. Biophys.
8
219-226
Solubilization and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast
1994
Decottignies, A.; Kolaczkowski, M.; Balzi, E.; Goffeau, A.
J. Biol. Chem.
269
12797-12803
Cobamides and ribonucleotide reduction. I. Cobamide stimulation of ribonucleotide reduction in extracts of Lactobacillus leichmannii
1965
Bakley, R.L.
J. Biol. Chem.
240
2173-2180
Purification and properties of cobamide-dependent ribonucleotide reductase from Lactobacillus leichmannii
1966
Goulian, M.; Beck, W.S.
J. Biol. Chem.
241
4233-4242
Ribonucleotide reductase from Thermus X-1, a thermophilic organism
1973
Sando, G.N.; Hogenkamp, H.P.C.
Biochemistry
12
3316-3322
Substrate and effector binding to ribonucleoside triphosphate reductase of Lactobacillus leichmannii
1974
Chen, A.K.; Bhan, A.; Hopper, S.; Abrams, R.; Franzen, J.S.
Biochemistry
13
654-661
Ribonucleotide reductase from Euglena gracilis. A 5-deoxyadenoslycobalamin-dependent enzyme
1974
Hamilton, F.D.
J. Biol. Chem.
249
4428-4434
Ribonucleoside triphosphate reductase from Lactobacillus leichmannii
1978
Blakley, R.L.
Methods Enzymol.
51
246-259
Adenosylcobalamin-dependent ribonucleotide reductase from the blue-green alga, Anabaena sp. Purification and partial characterization
1980
Gleason, F.K.; Frick, T.D.
J. Biol. Chem.
255
7728-7733
The mechanism of Lactobacillus leichmannii ribonucleotide reductase. Evidence for 3 carbon-hydrogen bond cleavage and a unique role for coenzyme B12
1986
Ashley, G.W.; Harris, G.; Stubbe, J.
J. Biol. Chem.
261
3958-3964
Immobilization of ribonucleotide reductase from Streptomyces aureofaciens
1989
Halicky, P.; Kollarova, M.; Kois, P.; Zelinka, J.
Collect. Czech. Chem. Commun.
54
2528-2541
Coenzyme B12-dependent ribonucleotide reductase: evidence for the participation of five cysteine residues in ribonucleotide reduction
1994
Booker, S.; Licht, S.; Broderick, J.; Stubbe, J.
Biochemistry
33
12676-12685
B12-dependent ribonucleotide reductases from deeply rooted eubacteria are structurally related to the aerobic enzyme from Escherichia coli
1997
Jordan, A.; Torrents, E.; Jeanthon, C.; Eliasson, R.; Hellman, U.; Wernstedt, C.; Barbe, J.; Gibert, I.; Reichard, P.
Proc. Natl. Acad. Sci. USA
94
13487-13492
The B12-dependent ribonucleotide reductase from the archaebacterium Thermoplasma acidophila: an evolutionary solution to the ribonucleotide reductase conundrum
1997
Tauer, A.; Benner, S.A.
Proc. Natl. Acad. Sci. USA
94
53-58
Ribonucleotide reduction in Pseudomonas species: simultaneous presence of active enzymes from different classes
1999
Jordan, A.; Torrents, E.; Sala, I.; Hellman, U.; Gibert, I.; Reichard, P.
J. Bacteriol.
181
3974-3980
Studies on the catalysis of carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: evidence for concerted carbon-cobalt bond homolysis and thiyl radical formation
1999
Licht, S.S.; Booker, S.; Stubbe, J.
Biochemistry
38
1221-1233
Thermodynamic and kinetic studies on carbon-cobalt bond homolysis by ribonucleoside triphosphate reductase: The importance of entropy in catalysis
1999
Licht, S.S.; Lawrence, C.C.; Stubbe, J.
Biochemistry
38
1234-1242
-
Ribonucleoside triphosphate reductase from Lactobacillus leichmannii: Kinetic evaluation of a series of adenosylcobalamin competitive inhibitors, [omega-(adenosin-5'-O-yl)alkyl]cobalamins, which mimic the post Co-C homolysis intermediate
1999
Suto, R.K.; Poppe, L.; Retey, J.; Finke, R.G.
Bioorg. Chem.
27
451-462
Adenosylcobalamin-dependent ribonucleoside triphosphate reductase from Lactobacillus leichmannii. Rapid, improved purification involving dGTP-based affinity chromatography plus biophysical characterization studies demonstrating enhanced, crystallographic level purity
1999
Suto, R.K.; Whalen, M.A.; Finke, R.G.
Prep. Biochem. Biotechnol.
29
273-309
Yeast ribonucleotide reductase has a heterodimeric iron-radical-containing subunit
2000
Chabes, A.; Domkin, V.; Larsson, G.; Liu, A.; Graslund, A.; Wijmenga, S.; Thelander, L.
Proc. Natl. Acad. Sci. USA
97
2474-2479
Crystal structure of the di-iron/radical protein of ribonucleotide reductase from Corynebacterium ammoniagenes
2002
Hoegbom, M.; Huque, Y.; Sjoeberg, B.M.; Nordlund, P.
Biochemistry
41
1381-1389
Comparison between avian and human prolyl 4-hydroxylases: studies on the holomeric enzymes and their constituent subunits
1992
Guzman, N.A.; Ascari, W.Q.; Cutroneo, K.R.; Desnick, R.J.
J. Cell. Biochem.
48
172-189
Stimulation of prolyl hydroxylase activity by chelating agents
1979
Takeda, K.; Katoh, F.; Kawai, S.; Konno, K.
Arch. Biochem. Biophys.
197
273-276
-
Properties of the phosphofructokinase isoenzymes from germinating cucumber seeds
1988
Cawood, M.E.; Botha, F.C.; Small, J.G.C.
J. Plant Physiol.
132
204-209
Cytosolic phosphofructokinase from spinach leaves: 2. The roles of magnesium and ATP
1989
Hausler, R.E.; Holtum, J.A.M.; Latzko, E.
Plant Physiol.
90
1506-1512
D-fructose 1-phosphate kinase and D-fructose 6-phosphate kinase from Aerobacter aerogenes. A comparative study of regulatory properties
1969
Sapico, V.; Anderson, R.L.
J. Biol. Chem.
244
6280-6288
Heterodimeric deoxynucleoside kinases of Lactobacillus acidophilus R-26: functional assignment of subunits using limited proteolysis controlled by end-product inhibitors
1994
Ikeda, S.; Ma, G.T.; Ives, D.H.
Biochemistry
33
5328-5334
Purine nucleoside kinases in human T- and B-lymphoblasts
1983
Yamada, Y.; Goto, H.; Ogasawara, N.
Biochim. Biophys. Acta
761
34-40
Properties of deoxycytidine kinase partially purified from L1210 cells
1968
Kessel, D.
J. Biol. Chem.
243
4739-4744
Mammalian deoxynucleoside kinase. I. Deoxycytidine kinase: purification, properties, and kinetic studies with cytosine arabinoside
1968
Momparler, R.L.; Fischer, G.A.
J. Biol. Chem.
243
4298-4304
Deoxycytidine kinase. II. Purification and general properties of the calf thymus enzyme
1970
Durham, J.P.; Ives, D.H.
J. Biol. Chem.
245
2276-2284
Deoxycytidine kinase. 3. Kinetics and allosteric regulation of the calf thymus enzyme
1970
Ives, D.H.; Durham, J.P.
J. Biol. Chem.
245
2285-2294
Purification of deoxycytidine kinases from two P815 murine neoplasms and their separation from deoxyguanosine kinase
1976
Meyers, M.B.; Kreis, W.
Arch. Biochem. Biophys.
177
10-15
Metabolism in deoxyribonucleotides. IV. Purification and properties of deoxycytidine kinase of calf thymus
1972
Kozai, Y.; Sonoda, S.; Kobayashi, S.; Sugino, Y.
J. Biochem.
71
485-496
Deoxycytidine kinase from calf thymus. Substrate and inhibitor specificity
1976
Krenitsky, T.A.; Tuttle, J.V.; Koszalka, G.W.; Chen, I.S.; Beacham, L.M.; Rideout, J.L.; Elion, G.B.
J. Biol. Chem.
251
4055-4061
Deoxycytidine kinase from calf thymus
1978
Ives, D.H.; Wang, S.M.
Methods Enzymol.
51
337-345
Selective inactivation of the deoxyadenosine phosphorylating activity of pure human deoxycytidine kinase: stabilization of different forms of the enzyme by substrates and biological detergents
1990
Kierdaszuk, B.; Eriksson, S.
Biochemistry
29
4109-4114
Purification and characterization of deoxycytidine kinase from acute myeloid leukemia cell mitochondria
1993
Wang, L.M.; Kucera, G.L.; Capizzi, R.L.
Biochim. Biophys. Acta
1202
309-316
Characterization of human deoxycytidine kinase. Correlation with cDNA sequences
1991
Eriksson, S.; Cederlund, E.; Bergman, T.; Jörnvall, H.; Bohman, C.
FEBS Lett.
280
363-366
Human deoxycytidine kinase: kinetic mechanism and end product regulation
1989
Kim, M.Y.; Ives, D.H.
Biochemistry
28
9043-9047
Kinetic properties and inhibition of human T lymphoblast deoxycytidine kinase
1989
Datta, N.S.; Shewach, D.S.; Mitchell, B.S.; Fox, I.H.
J. Biol. Chem.
264
9359-9364
Human T-lymphoblast deoxycytidine kinase: purification and properties
1989
Datta, N.S.; Shewach, D.S.; Hurley, M.C.; Mitchell, B.S.; Fox, I.H.
Biochemistry
28
114-123
Deoxycytidine kinase from human leukemic spleen: preparation and characteristics of homogeneous enzyme
1988
Bohman, C.; Eriksson, S.
Biochemistry
27
4258-4265
Affinity purification of human deoxycytidine kinase: avoidance of structural and kinetic artifacts arising from limited proteolysis
1988
Kim, M.Y.; Ikeda, S.; Ives, D.H.
Biochem. Biophys. Res. Commun.
156
92-98
A general method for purification of deoxycytidine kinase
1978
Baxter, A.; Currie, L.M.; Durham, J.P.
Biochem. J.
173
1005-1008
Nucleotide specificity of human deoxycytidine kinase
1992
Shewach, D.S.; Reynolds, K.K.; Hertel, L.
Mol. Pharmacol.
42
518-524
Deoxynucleoside phosphorylating enzymes in monkey and human tissues show great similarities, while mouse deoxycytidine kinase has a different substrate specificity
1991
Habteyesus, A.; Nordenskjoeld, A.; Bohman, C.; Eriksson, S.
Biochem. Pharmacol.
42
1829-1836
Deoxycytidine kinase: properties of the enzyme from human leukemic granulocytes
1975
Coleman, C.N.; Stoller, R.G.; Drake, J.C.; Chabner, B.A.
Blood
46
791-803
Mitochondrial and herpesvirus-specific deoxypyrimidine kinases
1975
Leung, W.C.; Dubbs, D.R.; Trkula, D.; Kit, S.
J. Virol.
16
486-497
Deoxynucleoside kinases from Lactobacilli. Separate interacting sites for deoxycytidine and deoxyadenosine
1977
Deibler, R.D.; Reznik, R.B.; Ives, D.H.
J. Biol. Chem.
252
8240-8244
Differences in kinetic properties of pure recombinant human and mouse deoxycytidine kinase
1995
Johansson, M.; Karlsson, A.
Biochem. Pharmacol.
50
163-168
-
Substrate specificities, expression and primary sequences of deoxynucleoside kinases; implications for chemotherapy
1997
Eriksson, S.; Wang, L.
Nucleosides Nucleotides
16
653-659
Substrate/inhibitor properties of human deoxycytidine kinase (dCK) and thymidine kinases (TK1 and TK2) towards the sugar moiety of nucleosides, including O'-alkyl analogues
1999
Kierdaszuk, B.; Krawiec, K.; Kazimierczuk, Z.; Jacobsson, U.; Johansson, N.G.; Munch-Petersen, B.; Eriksson, S.; Shugar, D.
Nucleosides Nucleotides
18
1883-1903
-
Purification of deoxycytidine kinase from various human leukemic cells by endo-product analog affinity chromatography
1995
Kim, M.Y.
J. Biochem. Mol. Biol.
28
281-289
Phosphorylation of 4'-thio-beta-D-arabinofuranosylcytosine and its analogs by human deoxycytidine kinase
2003
Someya, H.; Shaddix, S.C.; Tiwari, K.N.; Secrist, J.A., 3rd; Parker, W.B.
J. Pharmacol. Exp. Ther.
304
1314-1322
Preliminary X-ray studies on the GTP: AMP phosphotransferase from beef heart mitochondria
1983
Pai, E.F.; Schulz, G.E.; Tomasselli, A.G.; Noda, L.H.
J. Mol. Biol.
164
347-350
The amino acid sequence of GTP:AMP phosphotransferase from beef-heart mitochondria. Extensive homology with cytosolic adenylate kinase
1984
Wieland, B.; Tomasselli, A.G.; Noda, L.H.; Frank, R.; Schulz, G.E.
Eur. J. Biochem.
143
331-339
Transphosphorylations between nucleoside phosphates
1956
Ayengar, P.; Gibson, D.M.; Sanadi, D.R.
Biochim. Biophys. Acta
21
86-91
Rapid large-scale purification of pig heart nucleoside diphosphate kinase by affinity chromatography on Cibacron Blue 3G-A Sepharose
1981
Lascu, I.; Duc, M.; Cristea, A.
Anal. Biochem.
113
207-211
Crystal structure of the Awd nucleotide diphosphate kinase from Drosophila
1993
Chiadmi, M.; Morera, S.; Lascu, I.; Dumas, C.; Le Bras, G.; Veron, M.; Janin, J.
Structure
1
283-293
Isolation and kinetic studies of nucleoside diphosphokinase from human platelets and effects of cAMP phosphodiesterase inhibitors
1986
Lam, S.C.T.; Packham, M.A.
Biochem. Pharmacol.
35
4449-4455
Nucleoside diphosphate kinase from human erythrocytes: purification, molecular mass and subunit structure
1989
Presecan, E.; Vonica, A.; Lascu, I.
FEBS Lett.
250
629-632
Nucleoside diphosphate kinase from human erythrocytes. Structural characterization of the two polypeptide chains responsible for heterogeneity of the hexameric enzyme
1991
Gilles, A.M.; Presecan, E.; Vonica, A.; Lascu, I.
J. Biol. Chem.
266
8784-8789
Nucleoside diphosphate kinase from brain. Purification and effect on microtubule assembly in vitro
1984
Huitorel, P.; Simon, C.; Pantaloni, D.
Eur. J. Biochem.
144
233-241
Nucleoside diphosphokinase from beef heart cytosol. I. Physical and kinetic properties
1972
Colomb, M.G.; Chéruy, A.; Vignais, P.V.
Biochemistry
11
3370-3378
Nucleoside diphosphokinase from beef heart cytosol. II. Characterization of the phosphorylated intermediate
1972
Colomb, M.G.; Chéruy, A.; Vignais, P.V.
Biochemistry
11
3378-3386
Metabolism of deoxyribonucleotides. 3. Purification and some properties of nucleoside diphosphokinase of calf thymus
1966
Nakamura, H.; Sugino, Y.
J. Biol. Chem.
241
4917-4922
Membrane-associated nucleoside diphosphate kinase from rat liver. Purification, characterization, and comparison with cytosolic enzyme
1988
Kimura, N.; Shimada, N.
J. Biol. Chem.
263
4647-4653
Oligomeric structure and autophosphorylation of nucleoside diphosphate kinase from rat mucosal mast cells
1992
Hemmerich, S.; Pecht, I.
Biochemistry
31
4580-4587
A cromoglycate binding protein from rat mast cells of a leukemia line is a nucleoside diphosphate kinase
1992
Hemmerich, S.; Pecht, I.
Biochemistry
31
4574-4579
Isolation and characterization of a gene encoding rat nucleoside diphosphate kinase
1992
Ishikawa, N.; Shimada, N.; Munakata, Y.; Watanabe, K.; Kimura, N.
J. Biol. Chem.
267
14366-14372
Nucleoside diphosphate kinase from Xenopus oocytes; partial purification and characterization
1990
Buczynski, G.; Potter, R.L.
Biochim. Biophys. Acta
1041
296-304
Identification of nucleoside diphosphate kinase from pea microsomal membrane
1991
Finan, P.M.; White, I.R.; Findlay, J.B.C.; Millner, P.A.
Biochem. Soc. Trans.
20
10S
Purification and characterization of nucleoside diphosphate kinase from spinach leaves
1991
Nomura, T.; Fukui, T.; Ichikawa, A.
Biochim. Biophys. Acta
1077
47-55
The amino acid sequence of nucleoside diphosphate kinase I from spinach leaves, as deduced from the cDNA sequence
1992
Nomura, T.; Yatsunami, K.; Honda, A.; Sugimoto, Y.; Fukui, T.; Zang, J.; Yamamoto, J.; Ichikawa, A.
Arch. Biochem. Biophys.
297
42-45
Characterization of a low molecular mass autophosphorylating protein in cultured sugarcane cells and its identification as a nucleoside diphosphate kinase
1994
Moisyadi, S.; Dharmasiri, S.; Harrington, H.M.; Lukas, T.J.
Plant Physiol.
104
1401-1409
A plant nucleoside diphosphate kinase homologous to the human Nm23 gene product: purification and characterization
1994
Sommer, D.; Song, P.S.
Biochim. Biophys. Acta
1222
464-470
Crystallization and preliminary X-ray diffraction studies of nucleoside diphosphate kinase from Dictyostelium discoideum
1991
Dumas, C.; Lebras, G.; Wallet, V.; Lacombe, M.L.; Véron, M.; Janin, J.
J. Mol. Biol.
217
239-240
Saccharomyces cerevisiae nucleoside-diphosphate kinase: purification, characterization, and substrate specificity
1991
Jong, A.Y.; Ma, J.J.
Arch. Biochem. Biophys.
291
241-246
Nucleoside-triphosphate-nucleoside diphosphate transphosphorylase (nucleoside diphosphokinase). 1.Isolation of the crystalline enzyme from brewers´yeast
1964
Ratliff, R.L.; Weaver, R.H.; Lardy, H.A.; Kuby, S.A.
J. Biol. Chem.
239
301-309
Nucleoside triphosphate-nucleoside diphosphate transphosphorylase (nucleoside diphosphokinase). 3. Subunit structure of the crystalline enzyme from brewers yeast
1973
Palmieri, R.; Yue, R.H.; Jacobs, H.K.; Maland, L.; Wu, L.; Kuby, S.A.
J. Biol. Chem.
248
4486-4499
Nucleoside diphosphokinase from Salmonella typhimurium
1978
Ingraham, J.L.; Ginther, C.L.
Methods Enzymol.
51
371-375
Nucleoside diphosphokinase from human erythrocytes
1978
Agarwal, R.P.; Robison, B.; Parks, R.E.
Methods Enzymol.
51
376-386
Kinetic studies on the inhibition of nucleoside diphosphate kinase by desdanine
1974
Saeki, T.; Hori, M.; Umezawa, H.
J. Biochem.
76
623-629
Crystal structure of Myxococcus xanthus nucleoside diphosphate kinase and its interaction with a nucleotide substrate at 2.0 A resolution
1993
Williams, R.L.; Oren, D.A.; Muñoz-Dorado, J.; Inoue, S.; Inoue, M.; Arnold, E.
J. Mol. Biol.
234
1230-1247
Nucleoside diphosphate kinase from Escherichia coli; its overproduction and sequence comparison with eukaryotic enzymes
1991
Hama, H.; Almaula, N.; Lerner, C.G.; Inouye, S.; Inoue, M.
Gene
105
31-36
-
Nucleoside diphosphokinases
1973
Parks, R.E.; Agarwal, R.P.
The Enzymes,3rd Ed. (Boyer,P. D. ,ed. )
8
307-333
Nucleoside-diphosphate kinase from Streptomyces coelicolor
1996
Brodbeck, M.; Rohling, A.; Wohlleben, W.; Thompson, C.J.; Susstrunk, U.
Eur. J. Biochem.
239
208-213
Nucleoside diphosphate kinase required for coleoptile elongation in rice
2000
Pan, L.; Kawai, M.; Yano, A.; Uchimiya, H.
Plant Physiol.
122
447-452
Stability of Natrialba magadii NDP kinase: Comparisons with other halophilic proteins
2002
Polosina, Y.; Zamyatkin, D.F.; Kostyukova, A.S.; Filimonov, V.; Fedorov, O.V.
Extremophiles
6
135-142
Nucleoside diphosphate kinase from haloalkaliphilic archaeon Natronobacterium magadii: purification and characterization
1998
Polosina, Y.Y.; Jarrell, K.F.; Fedorov, O.V.; Kostyukova, A.S.
Extremophiles
2
333-338
Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gb subunits
2003
Cuello, F.; Schulze, R.A.; Heemeyer, F.; Meyer, H.E.; Lutz, S.; Jakobs, K.H.; Niroomand, F.; Wieland, T.
J. Biol. Chem.
278
7220-7226
Characterization and cloning of a nucleoside-diphosphate kinase targeted to matrix of mitochondria in pigeon
1997
Lambeth, D.O.; Mehus, J.G.; Ivey, M.A.; Milavetz, B.I.
J. Biol. Chem.
272
24604-24611
The nucleoside diphosphate kinase of Mycobacterium smegmatis: identification of proteins that modulate specificity of nucleoside triphosphate synthesis by the enzyme
1997
Shankar, S.; Hershberger, C.D.; Chakrabarty, A.M.
Mol. Microbiol.
24
477-487
Cloning, expression, and efficient purification in Escherichia coli of a halophilic nucleoside diphosphate kinase from the moderate halophile Halomonas sp. #593
2003
Yonezawa, Y.; Tokunaga, H.; Ishibashi, M.; Taura, S.; Tokunaga, M.
Protein Expr. Purif.
27
128-133
Nucleoside diphosphate kinase of Trypanosoma brucei
2000
Hunger-Glaser, I.; Hemphill, A.; Shalaby, T.; Hanni, M.; Seebeck, T.
Gene
257
251-257
The human Nm23/nucleoside diphosphate kinases
2000
Lacombe, M.L.; Milon, L.; Munier, A.; Mehus, J.G.; Lambeth, D.O.
J. Bioenerg. Biomembr.
32
247-258
Studies on the incorporation of deoxyribonucleotides and ribonucleotides into deoxyribonucleic acid
1962
Krakow, J.S.; Coutsogeorgopoulos, C.; Canellakis, E.S.
Biochim. Biophys. Acta
55
639-650
Qbeta RNA replicase and protein synthesis elongation factors EF-Tu and EF-Ts
1979
Blumenthal, T.
Methods Enzymol.
60
628-638
-
Qbeta replicase
1982
Blumenthal, T.
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
15
267-279
Function and structure in ribonucleic acid Phage Qbeta ribonucleic acid replicase. Effect of inhibitors of EF-Tu on ribonucleic acid synthesis and renaturation of active enzyme
1976
Brown, S.; Blumenthal, T.
J. Biol. Chem.
251
2749-2753
Characterization and specificity of soluble RNA polymerase of Brome mosaic virus
1973
Hadidi, A.; Fraenkel-Conrat, H.
Virology
52
363-372
Replication of viral nucleic acids. II. Inhibition of Q replicase by sulfhydryl-blocking reagents
1972
Ohki, K.; Hori, K.
Biochim. Biophys. Acta
281
233-243
Cucumber mosaic virus-induced RNA polymerase: partial purification and properties of the template-free enzyme
1974
Clark, G.L.; Peden, K.W.C.; Symons, R.H.
Virology
62
434-444
Activity of Foot-and-mouth disease virus RNA-dependent RNA polymerase in vitro: inhibition by polyamines and poly(amino acid)s
1973
Lazarus, L.H.; Itin, A.
Arch. Biochem. Biophys.
156
154-160
Isolation and properties of the replicase of Encephalomyocarditis virus
1976
Traub, A.; Diskin, B.; Rosenberg, H.; Kalmar, E.
J. Virol.
18
375-382
Purification and properties of the ribonucleic acid-dependent ribonucleic acid polymerase from Halobacterium cutirubrum
1972
Louis, B.G.; Fitt, P.S.
Biochem. J.
128
755-762
In vitro replication of Cowpea mosaic virus RNA: I. Isolation and properties of the membrane-bound replicase
1974
Zabel, P.; Weenen-Swaans, H.; van Kammen, A.
J. Virol.
14
1049-1055
Characterization of Kunjin virus RNA-dependent RNA polymerase: reinitiation of synthesis in vitro
1987
Chu, P.W.G.; Westaway, E.G.
Virology
157
330-337
Purification and molecular structure of RNA polymerase from Influenza virus A/PR8
1990
Honda, A.; Mukaigawa, J.; Yokoiyama, A.; Kato, A.; Ueda, S.; Nagata, K.; Krystal, M.; Nayak, D.P.; Ishihama, A.
J. Biochem.
107
624-628
Purification and properties of Poliovirus RNA polymerase expressed in Escherichia coli
1989
Plotch, S.J.; Palant, O.; Gluzman, Y.
J. Virol.
63
216-225
Characterization of Cucumber mosaic virus RNA-dependent RNA polymerase
1991
Quadt, R.; Jaspars, E.M.J.
FEBS Lett.
279
273-276
Purification and characterization of Brome mosaic virus RNA-dependent RNA polymerase
1990
Quadt, R.; Jaspars, E.M.J.
Virology
178
189-194
Partial purification and characterization of Foxtail mosaic potexvirus RNA-dependent RNA polymerase
1993
Rouleau, M.; Bancroft, J.B.; Mackie, G.A.
Virology
197
695-703
RNA-directed RNA polymerase from tomato leaves. I. Purification and physical properties
1993
Schiebel, W.; Haas, B.; Marinkovic, S.; Klanner, A.; Sänger, H.L.
J. Biol. Chem.
268
11851-11857
RNA-directed RNA polymerase from tomato leaves. II. Catalytic in vitro properties
1993
Schiebel, W.; Haas, B.; Marinkovic, S.; Klanner, A.; Sänger, H.L.
J. Biol. Chem.
268
11858-11867
Further characterization of Mouse hepatitis virus RNA-dependent RNA polymerases
1984
Brayton, P.R.; Stohlman, S.A.; Lai, M.M.C.
Virology
133
197-201
Inhibition of Poliovirus polymerase by guanidine in vitro
1982
Tershak, D.R.
J. Virol.
41
313-318
Purification of a soluble template-dependent Rhinovirus RNA polymerase and its dependence on a host cell protein for viral RNA synthesis
1985
Morrow, C.D.; Lubrinski, J.; Hocko, J.; Gibbons, G.F.; Dasgupta, A.
J. Virol.
53
266-272
Characterization of West Nile virus RNA-dependent RNA polymerase and cellular terminal adenylyl and uridylyl transferases in cell-free extracts
1986
Grun, J.B.; Brinton, M.A.
J. Virol.
60
1113-1124
-
Properties of a solubilized replicase isolated from corn infected with Maize dwarf mosaic virus
1986
Donofrio, J.C.; Kuchta, J.; Moore, R.; Kaczmarczyk, W.
Can. J. Microbiol.
32
637-644
RNA polymerase from Tobacco necrosis virus-infected and uninfected tobacco. II. Properties of the bound and soluble polymerases and the nature of their products
1977
Stussi-Garaud, C.; Lemius, J.; Fraenkel-Conrat, H.
Virology
81
224-236
Properties of solubilized RNA-dependent RNA polymerase from Alfalfa mosaic virus-infected and healthy tobacco plants
1978
Clerx, C.M.; Bol, J.F.
Virology
91
453-463
Cucumber mosaic virus-induced RNA replicase: solubilisation and partial purification of the particulate enzyme
1981
Gill, D.S.; Kumarasamy, R.; Symons, R.H.
Virology
113
1-8
Purification of a host-encoded RNA-dependent RNA-polymerase from cowpea mosaic-virus-infected cowpea leaves
1982
Dorssers, L.; Zabel, P.; van der Meer, J.; van Kammen, A.
Virology
116
236-249
Extensive purification of the cucumber mosaic virus-induced RNA replicase
1979
Kumarasamy, R.; Symons, R.H.
Virology
96
622-632
Characterization of RNA polymerase products of Nebraska calf diarrhea virus and SA11 rotavirus
1981
Bernstein, J.M.; Hruska, J.F.
J. Virol.
37
1071-1074
In vitro replication of Bacteriophage GA RNA. Subunit structure and catalytic properties of GA replicase
1981
Yonesaki, T.; Haruna, I.
J. Biochem.
89
741-750
Interaction of Qbeta RNA replicase with guanine nucleotides. Different modes of inhibition and inactivation
1977
Blumenthal, T.
Biochim. Biophys. Acta
478
201-208
Biochemical and kinetic analyses of NS5B RNA-dependent RNA polymerase of the Hepatitis C virus
1998
Lohmann, V.; Roos, A.; Körner, F.; Koch, J.O.; Bartenschlager, R.
Virology
249
108-118
Isolation and characterization of an RNA-dependent RNA polymerase from Black beetle virus-infected Drosophila melanogaster cells
1981
Guarino, L.A.; Kaesberg, P.
J. Virol.
40
379-386
Characterization of an RNA-dependent RNA polymerase activity associated with Measles virus
1978
Seifried, A.S.; Albrecht, P.; Milstien, J.B.
J. Virol.
25
781-787
Characterization of the RNA-dependent RNA polymerase of tobacco leaves
1979
Ikegami, M.; Fraenkel-Conrat, H.
J. Biol. Chem.
254
149-154
-
Purification and characterization of recombinant Hepatitis C virus replicase
1999
Park, C.; Kee, Y.; Lee, J.; Oh, J.; Park, J.; Myung, H.
J. Microbiol. Biotechnol.
9
881-884
Characterization of soluble Hepatitis C virus RNA-dependent RNA polymerase expressed in Escherichia coli
1999
Ferrari, E.; Wright-Minogue, J.; Fang, J.W.; Baroudy, B.M.; Lau, J.Y.; Hong, Z.
J. Virol.
73
1649-1654
Identification and characterization of an RNA-dependent RNA polymerase activity within the nonstructural protein 5B region of Bovine viral diarrhea virus
1998
Zhong, W.; Gutshall, L.L.; Del Vecchio, A.M.
J. Virol.
72
9365-9369
Characterization of the in vitro activity of the RNA-dependent RNA polymerase associated with the ribonucleoproteins of Rice Hoja Blanca tenuivirus
1997
Nguyen, M.; Ramirez, B.C.; Goldbach, R.; Haenni, A.L.
J. Virol.
71
2621-2627
Biochemical characterization of a Hepatitis C virus RNA-dependent RNA polymerase mutant lacking the C-terminal hydrophobic sequence
2000
Tomei, L.; Vitale, R.L.; Incitti, I.; Serafini, S.; Altamura, S.; Vitelli, A.; De Francesco, R.
J. Gen. Virol.
81
759-767
Characterization of the expression, intracellular localization, and replication complex association of the putative Mouse hepatitis virus RNA-dependent RNA polymerase
2003
Brockway, S.M.; Clay, C.T.; Lu, X.T.; Denison, M.R.
J. Virol.
77
10515-10527
Mutational analysis of the structure and functions of Hepatitis C virus RNA-dependent RNA polymerase
2001
Qin, W.; Yamashita, T.; Shirota, Y.; Lin, Y.; Wei, W.; Murakami, S.
Hepatology
33
728-737
Characterization of an RNA-dependent RNA polymerase activity associated with La France isometric virus
1997
Goodin, M.M.; Schlagnhaufer, B.; Weir, T.; Romaine, C.P.
J. Virol.
71
2264-2269
Biochemical properties of Hepatitis C virus NS5B RNA-dependent RNA polymerase and identification of amino acid sequence motifs essential for enzymic activity
1997
Lohmann, V.; Korner, F.; Herian, U.; Bartenschlager, R.
J. Virol.
71
8416-8428
Identification and characterization of the Escherichia coli-expressed RNA-dependent RNA polymerase of Bamboo mosaic virus
1998
Li, Y.I.; Cheng, Y.M.; Huang, Y.L.; Tsai, C.H.; Hsu, Y.H.; Meng, M.
J. Virol.
72
10093-10099
Biochemical characterization of Rhinovirus RNA-dependent RNA polymerase
2002
Hung, M.; Gibbs, C.S.; Tsiang, M.
Antiviral Res.
56
99-114
Characterization of RNA synthesis, replication mechanism, and in vitro RNA-dependent RNA polymerase activity of Japanese encephalitis virus
2003
Uchil, P.D.; Satchidanandam, V.
Virology
307
358-371
Specificity and mechanism analysis of Hepatitis C virus RNA-dependent RNA polymerase
2000
Johnson, R.B.; Sun, X.L.; Hockman, M.A.; Villarreal, E.C.; Wakulchik, M.; Wang, Q.M.
Arch. Biochem. Biophys.
377
129-134
Characterization of RNA-dependent RNA polymerase activity of CSFV NS5B proteins expressed in Escherichia coli
2003
Xiao, M.; Wang, Y.; Chen, J.; Li, B.
Virus Genes
27
67-74
The Hepatitis C virus NS5B RNA-dependent RNA polymerase activity and susceptibility to inhibitors is modulated by metal cations
2000
Alaoui-Lsmaili, M.H.; Hamel, M.; L'Heureux, L.; Nicolas, O.; Bilimoria, D.; Labonte, P.; Mounir, S.; Rando, R.F.
J. Hum. Virol.
3
306-316
Kinetic properties of Qb replicase, an RNA dependent RNA polymerase
2002
Nakaishi, T.; Iio, K.; Yamamoto, K.; Urabe, I.; Yomo, T.
J. Biosci. Bioeng.
93
322-327
Identification and properties of the RNA-dependent RNA polymerase of Hepatitis C virus
1996
Behrens, S.E.; Tomei, L.; De Francesco, R.
EMBO J.
15
12-22
Poliovirus RNA-dependent RNA polymerase (3Dpol): structural, biochemical, and biological analysis of conserved structural motifs A and B
2000
Gohara, D.W.; Crotty, S.; Arnold, J.J.; Yoder, J.D.; Andino, R.; Cameron, C.E.
J. Biol. Chem.
275
25523-25532
Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity
2002
Shirota, Y.; Luo, H.; Qin, W.; Kaneko, S.; Yamashita, T.; Kobayashi, K.; Murakami, S.
J. Biol. Chem.
277
11149-11155
RNA-dependent RNA polymerase activity of the soluble recombinant Hepatitis C virus NS5B protein truncated at the C-terminal region
1998
Yamashita, T.; Kaneko, S.; Shirota, Y.; Qin, W.; Nomura, T.; Kobayashi, K.; Murakami, S.
J. Biol. Chem.
273
15479-15486
Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase
2003
Wang, M.; Ng, K.K.S.; Cherney, M.M.; Chan, L.; Yannopoulos, C.G.; Bedard, J.; Morin, N.; Nguyen-Ba, N.; Alaoui-Ismaili, M.H.; Bethell, R.C.; James, M.N.G.
J. Biol. Chem.
278
9489-9495
Only a small fraction of purified hepatitis C RNA-dependent RNA polymerase is catalytically competent: implications for viral replication and in vitro assays
2000
Carroll, S.S.; Sardana, V.; Yang, Z.; Jacobs, A.R.; Mizenko, C.; Hall, D.; Hill, L.; Zugay-Murphy, J.; Kuo, L.C.
Biochemistry
39
8243-8249
Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase
2002
Ng, K.K.; Cherney, M.M.; Vazquez, A.L.; Machin, A.; Alonso, J.M.; Parra, F.; James, M.N.
J. Biol. Chem.
277
1381-1387
Crystallization and preliminary X-ray crystallographic studies on the Bacteriophage phi6 RNA-dependent RNA polymerase
2000
Butcher, S.J.; Makeyev, E.V.; Grimes, J.M.; Stuart, D.I.; Bamford, D.H.
Acta Crystallogr. Sect. D
56
1473-1475
Crystal structure of the RNA-dependent RNA polymerase from Hepatitis C virus reveals a fully encircled active site
1999
Lesburg, C.A.; Cable, M.B.; Ferrari, E.; Hong, Z.; Mannarino, A.F.; Weber, P.C.
Nat. Struct. Biol.
6
937-943
Crystal structure of the RNA-dependent RNA polymerase of Hepatitis C virus
1999
Bressanelli, S.; Tomei, L.; Roussel, A.; Incitti, I.; Vitale, R.L.; Mathieu, M.; De Francesco, R.; Rey, F.A.
Proc. Natl. Acad. Sci. USA
96
13034-13039
Evolutionary connection between the catalytic subunits of DNA-dependent RNA polymerases and eukaryotic RNA-dependent RNA polymerases and the origin of RNA polymerases
2003
Iyer, L.M.; Koonin, E.V.; Aravind, L.
BMC Struct. Biol.
3
1-23
Yeast diadenosine 5,5-P1,P4-tetraphosphate alpha,beta-phosphorylase behaves as a dinucleoside tetraphosphate synthetase
1987
Brevet, A.; Coste, H.; Fromant, M.; Plateau, P.; Blanquet, S.
Biochemistry
26
4763-4768
Molecular structures of DNA-dependent RNA polymerases (II) from calf thymus and rat liver
1971
Weaver, R.F.; Blatti, S.P.; Rutter, W.J.
Proc. Natl. Acad. Sci. USA
68
2994-2999
Mammalian RNA polymerases
1973
Jacob, S.T.
Prog. Nucleic Acid Res. Mol. Biol.
13
93-126
-
Cyanobacterial DNA-dependent RNA polymerase
1988
Borbely, G.; Schneider, G.J.
Methods Enzymol.
167
592-599
RNA elongation by RNA polymerase II is not inhibited by N-ethylmaleimide or iodoacetamide
1990
Krueger, R.C.
Arch. Biochem. Biophys.
278
475-477
Purification and lipid-layer crystallization of yeast RNA polymerase II
1990
Edwards, A.M.; Darst, S.A.; Feaver, W.J.; Thompson, N.E.; Burgess, R.R.; Kornberg, R.D.
Proc. Natl. Acad. Sci. USA
87
2122-2126
Tagetitoxin: a new inhibitor of eukaryotic transcription by RNA polymerase III
1990
Steinberg, T.H.; Mathews, D.E.; Durbin, R.D.; Burgess, R.R.
J. Biol. Chem.
265
499-505
Purification and characterization of DNA dependent RNA polymerase from Staphylococcus aureus
1995
Deora, R.; Mira, T.K.
Biochem. Biophys. Res. Commun.
208
610-616
Highly purified pea chloroplast RNA polymerase transcribes both rRNA and mRNA genes
1991
Rajasekhar, V.K.; Sun, E.; Meeker, R.; Wu, B.W.; Tewari, K.T.
Eur. J. Biochem.
195
215-228
Purification and characterization of the DNA-dependent RNA polymerase from Clostridium acetobutylicum
1991
Pich, A.; Baghl, H.
J. Bacteriol.
173
2120-2124
Characterization of the RNA polymerases of Crithidia fasciculata
1991
Köck, J.; Cornelissen, A.W.C.A.
Mol. Microbiol.
5
835-842
Accuracy of wheat-germ RNA polymerase II. General enzymatic properties and effect of template conformational transition from right-handed B-DNA to left-handed Z-DNA
1992
de Mercoyrol, L.; Corda, Y.; Job, C.; Job, D.
Eur. J. Biochem.
206
49-58
Isolation and characterization of mutant bacteriophage T7 RNA polymerases
1992
Patra, D.; Lafer, E.M.; Sousa, R.
J. Mol. Biol.
224
307-318
Isolation and physical properties of the DNA-directed RNA polymerase from Thermus thermophilus HB8
1990
Wnendt, S.; Hartmann, R.K.; Ulbrich, N.; Erdmann, V.A.
Eur. J. Biochem.
191
467-472
Purification of the DNA-dependent RNA polymerase from the myxobacterium Stigmatella aurantiaca
1992
Heidelbach, M.; Skladny, H.; Schairer, H.U.
J. Bacteriol.
174
2733-2735
Recombinant RNA polymerase: inducible overexpression, purification and assembly of Escherichia coli rpo gene products
1990
Zalenskaya, K.; Lee, J.; Gujuluva, C.N.; Shin, Y.K.; Slutsky, M.; Goldfarb, A.
Gene
89
7-12
Purification and characterization of a DNA-dependent RNA polymerase from Pseudomonas putida
1992
Fujita, M.; Amemura, A.
Biosci. Biotechnol. Biochem.
56
1797-1800
Purification and partial characterization of the DNA-dependent RNA polymerase from Rickettsia prowazekii
1990
Ding, H.F.; Winkler, H.H.
J. Bacteriol.
172
5624-5630
Subunits of the Schizosaccharomyces pombe RNA polymerase II: enzyme purification and structure of the subunit 3 gene
1993
Azuma, Y.; Yamagishi, M.; Ishihama, A.
Nucleic Acids Res.
21
3749-3754
The DNA-dependent RNA-polymerase of Thermotoga maritima; characterisation of the enzyme and the DNA-sequence of the genes for the large subunits
1993
Palm, P.; Schleper, C.; Arnold-Ammer, I.; Holz, I.; Meier, T.; Lottspeich, F.; Zillig, W.
Nucleic Acids Res.
21
4904-4908
-
Crystallographic structure of phage T7 RNA polymerase at resolution of 4.0 A
1990
Chung, Y.J.; Sousa, R.; Rose, J.P.; Lafer, E.; Wang, B.C.
Struct. Funct. Nucleic Acids Proteins (Wu, F. Y. -H. , Wu, C. -W. , Eds. ) Raven
New York
55-59
Structure and function of DNA-dependent RNA-polymerase
1971
Sethi, V.S.
Prog. Biophys. Mol. Biol.
23
67-101
-
Purification and characterization of a soluble DNA-dependent chloroplast RNA polymerase from Pisum sativum
1998
Boyer, A.S.; Hallick, R.B.
Plant Sci.
137
13-32
Isolation and characterisation of a chick cDNA encoding the RNA polymerase common subunit RPB6
2000
Kaarbo, M.; Crane, D.I.; Murrell, W.G.
DNA Seq.
11
155-162
Chromatographic separation of DNA dependent RNA polymerases and molecular properties of RNA polymerase II from a Leishmania spp
1997
Sadhukhan, P.K.; Cgakraborty, A.K.; Dasgupta, A.; Majumder, H.K.
Mol. Cell. Biochem.
171
105-114
Determinants of ribose specificity in RNA polymerization: effects of Mn2+ and deoxynucleoside monophosphate incorporation into transcripts
1997
Huang, Y.; Beaudry, A.; McSwiggen, J.; Sousa, R.
Biochemistry
36
13718-13728
Identification and properties of the largest subunit of the DNA-dependent RNA polymerase of fish lymphocystis disease virus: dramatic difference in the domain organization in the family Iridoviridae
1995
Müller, M.; Schnitzler, P.; Koonin, E.V.; Darai, G.
J. Gen. Virol.
76
1099-1107
RNA Polymerase of Aquifex pyrophilus: Implications for the evolution of the bacterial rpoBC operon and extremely termophilic bacteria
1999
Klenk, H.P.; Meier, T.D.; Durovic, P.; Schwass, V.; Lottspeich, F.; Dennis, P.P.; Zillig, W.
J. Mol. Evol.
48
528-541
Structural study of the yeast RNA polymerase A electron microscopy of lipid-bound molecules and two-dimensional crystals
1992
Schultz, P.; Celia, H.; Riva, M.; Darst, S.A.; Colin, P.; Kornberg, R.D.; Sentenac, A.; Oudet, P.
J. Mol. Biol.
216
353-362
Structural basis of transcription: An RNA polymerase II elongation complex at 3.3 A resolution
2001
Gnatt, A.L.; Cramer, P.; Fu, J.; Bushnell, D.A.; Kornberg, R.D.
Science
292
1876-1881
Purification and initial characterization of RNA polymerase from Thermus thermophilus strain HB8
2000
Xue, Y.; Hogan, B.P.; Erie, D.A.
Biochemistry
39
14356-14362
Three-dimensional model of yeast RNA polymerase I determined by electron microscopy of two-dimensional crystals
1993
Schultz, P.; Celia, H.; Riva, M.; Sentenac, A.; Oudet, P.
EMBO J.
12
2601-2607
Formation and crystallization of yeast RNA polymerase II elongation complexes
1997
Gnatt, A.; Fu, J.; Kornberg, R.D.
J. Biol. Chem.
272
30799-30805
Interaction between nucleoside triphosphate phosphohydrolase I and the H4L subunit of the viral RNA polymerase is required for vaccinia virus early gene transcript release
2000
Mohamed, M.R.; Niles, E.G.
J. Biol. Chem.
275
25798-25804
Behavior of T7 RNA polymerase and Mammalian RNA polymerase II at site-specific cisplatin adducts in the template DNA
2003
Tornaletti, S.; Patrick, S.M.; Turchi, J.J.; Hanawalt, P.C.
J. Biol. Chem.
278
35791-35797
Effects of substitutions in a conserved DX2GR sequence motif, found in many DNA-dependent nucleotide polymerases, on transcription by T7 RNA polymerase
2002
Imburgio, D.; Anikin, M.; McAllister, W.T.
J. Mol. Biol.
319
37-51
Pre-steady-state and steady-state kinetic studies on transcription initiation catalyzed by T7 RNA polymerase and its active-site mutants K631R and Y639F
1998
Woody, A.Y.M.; Osumi-Davis, P.A.; Hiremath, M.M.; Woody, R.W.
Biochemistry
37
15958-15964
Conformation and DNA binding properties of a single-stranded DNA binding region of sigma 70 subunit from Escherichia coli RNA polymerase are modulated by an interaction with the core enzyme
1998
Callaci, S.; Heyduk, T.
Biochemistry
37
3312-3320
Branched-chain alpha-keto acid dehydrogenase phosphatase and its inhibitor protein from bovine kidney
1988
Damuni, Z.; Reed, L.J.
Methods Enzymol.
166
321-329
Biochemical evidence for an ecto alkaline phosphodiesterase I in human airways
2000
Picher, M.; Boucher, R.C.
Am. J. Respir. Cell Mol. Biol.
23
255-261
DNA-dependent RNA polymerase from Pseudomonas aeruginosa
1987
Allan, B.; Kropinski, A.M.
Biochem. Cell Biol.
65
776-782
Enzymatic characterization of the full-length and C-terminally truncated Hepatitis C virus RNA polymerases: function of the last 21 amino acids of the C terminus in template binding and RNA synthesis
2004
Vo, N.V.; Tuler, J.R.; Lai, M.M.C.
Biochemistry
43
10579-10591
Poliovirus RNA-dependent RNA polymerase (3Dpol): pre-steady-state kinetic analysis of ribonucleotide incorporation in the presence of Mg2+
2004
Arnold, J.J.; Cameron, C.E.
Biochemistry
43
5126-5137
T7 RNA polymerase mediates fast promoter-independent extension of unstable nucleic acid complexes
2004
Zaher, H.S.; Unrau, P.J.
Biochemistry
43
7873-7880
Structural basis for substrate selection by T7 RNA polymerase
2004
Temiakov, D.; Patlan, V.; Anikin, M.; McAllister, W.T.; Yokoyama, S.; Vassylyev, D.G.
Cell
116
381-391
Requirements for West Nile virus (-)- and (+)-strand subgenomic RNA synthesis in vitro by the viral RNA-dependent RNA polymerase expressed in Escherichia coli
2004
Nomaguchi, M.; Teramoto, T.; Yu, L.; Markoff, L.; Padmanabhan, R.
J. Biol. Chem.
279
12141-12151
Sendai virus RNA-dependent RNA polymerase L protein catalyzes cap methylation of virus-specific mRNA
2005
Ogino, T.; Kobayashi, M.; Iwama, M.; Mizumoto, K.
J. Biol. Chem.
280
4429-4435
Back-priming mode of phi6 RNA-dependent RNA polymerase
2005
Laurila, M.R.; Salgado, P.S.; Stuart, D.I.; Grimes, J.M.; Bamford, D.H.
J. Gen. Virol.
86
521-526
De novo initiation pocket mutations have multiple effects on hepatitis C virus RNA-dependent RNA polymerase activities
2004
Ranjith-Kumar, C.T.; Sarisky, R.T.; Gutshall, L.; Thomson, M.; Kao, C.C.
J. Virol.
78
12207-12217
The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase
2004
Salgado, P.S.; Makeyev, E.V.; Butcher, S.J.; Bamford, D.H.; Stuart, D.I.; Grimes, J.M.
Structure
12
307-316
Crystal structure of a hyperthermophilic archaeal acylphosphatase from Pyrococcus horikoshii - structural insights into enzymatic catalysis, thermostability, and dimerization
2005
Cheung, Y.Y.; Lam, S.Y.; Chu, W.K.; Allen, M.D.; Bycroft, M.; Wong, K.B.
Biochemistry
44
4601-4611
Coat proteins of two filamentous plant viruses display NTPase activity in vitro
2005
Rakitina, D.V.; Kantidze, O.L.; Leshchiner, A.D.; Solovyev, A.G.; Novikov, V.K.; Morozov, S.Y.; Kalinina, N.O.
FEBS Lett.
579
4955-4960
A novel family of P-loop NTPases with an unusual phyletic distribution and transmembrane segments inserted within the NTPase domain
2004
Aravind, A.L.; Lakshminarayan, I.L.; Leipe, D.D.; Koonin, E.V.
Genome Biol.
5
R30
The RNA helicase, nucleotide 5'-triphosphatase, and RNA 5'-triphosphatase activities of Dengue virus protein NS3 are Mg2+-dependent and require a functional Walker B motif in the helicase catalytic core
2004
Benarroch, D.; Selisko, B.; Locatelli Giada, A.; Maga, G.; Romette, J.L.; Canard, B.
Virology
328
208-218
The structure of human deoxycytidine kinase in complex with clofarabine reveals key interactions for prodrug activation
2006
Zhang, Y.; Secrist, J.A.; Ealick, S.E.
Acta Crystallogr. Sect. D
62
133-139
Improved crystallization of the coxsackievirus B3 RNA-dependent RNA polymerase
2007
Jabafi, I.; Selisko, B.; Coutard, B.; De Palma, A.M.; Neyts, J.; Egloff, M.P.; Grisel, S.; Dalle, K.; Campanacci, V.; Spinelli, S.; Cambillau, C.; Canard, B.; Gruez, A.
Acta Crystallogr. Sect. F
63
495-498
Identification and characterization of RNA-dependent RNA polymerase activity in recombinant Japanese encephalitis virus NS5 protein
2007
Yu, F.; Hasebe, F.; Inoue, S.; Mathenge, E.G.; Morita, K.
Arch. Virol.
152
1859-1869
Activation of deoxycytidine kinase by protein kinase inhibitors and okadaic acid in leukemic cells
2003
Smal, C.; Cardoen, S.; Betrand, L.; Delacauw, A.; Ferrant, A.; Van den Berghe, G.; Van den Neste, E.; Bontemps, F.
Biochem. Pharmacol.
69
95-103
Structural basis for the preference of UTP over ATP in human deoxycytidine kinase: Illuminating the role of main-chain reorganization
2006
Godsey, M.H.; Ort, S.; Sabini, E.; Konrad, M.; Lavie, A.
Biochemistry
45
452-461
Structure-activity relationship (SAR) studies of quinoxalines as novel HCV NS5B RNA-dependent RNA polymerase inhibitors
2007
Rong, F.; Chow, S.; Yan, S.; Larson, G.; Hong, Z.; Wu, J.
Bioorg. Med. Chem. Lett.
17
1663-1666
The relation between deoxycytidine kinase activity and the radiosensitising effect of gemcitabine in eight different human tumour cell lines
2006
Pauwels, B.; Korst, A.E.; Pattyn, G.G.; Lambrechts, H.A.; Kamphuis, J.A.; De Pooter, C.M.; Peters, G.J.; Lardon, F.; Vermorken, J.B.
BMC Cancer
6
142
Biochemical characterization of a recombinant Japanese encephalitis virus RNA-dependent RNA polymerase
2007
Kim, Y.G.; Yoo, J.S.; Kim, J.H.; Kim, C.M.; Oh, J.W.
BMC Mol. Biol.
8
59
Cyclopentenyl cytosine-induced activation of deoxycytidine kinase increases gemcitabine anabolism and cytotoxicity in neuroblastoma
2006
Bierau, J.; van Gennip, A.H.; Leen, R.; Meinsma, R.; Caron, H.N.; van Kuilenburg, A.B.
Cancer Chemother. Pharmacol.
57
105-113
Positive regulation of deoxycytidine kinase activity by phosphorylation of Ser-74 in B-cell chronic lymphocytic leukemia lymphocytes
2007
Smal, C.; Van Den Neste, E.; Maerevoet, M.; Poire, X.; Theate, I.; Bontemps, F.
Cancer Lett.
253
68-73
Immunohistochemical and genetic evaluation of deoxycytidine kinase in pancreatic cancer: relationship to molecular mechanisms of gemcitabine resistance and survival
2006
Sebastiani, V.; Ricci, F.; Rubio-Viqueira, B.; Rubio-Viquiera, B.; Kulesza, P.; Yeo, C.J.; Hidalgo, M.; Klein, A.; Laheru, D.; Iacobuzio-Donahue, C.A.
Clin. Cancer Res.
12
2492-2497
Identification of a putative mitochondrial RNA polymerase from Physarum polycephalum: characterization, expression, purification, and transcription in vitro
2006
Miller, M.L.; Antes, T.J.; Qian, F.; Miller, D.L.
Curr. Genet.
49
259-271
Bacterial RNA polymerase: a promising target for the discovery of new antimicrobial agents
2007
Chopra, I.
Curr. Opin. Investig. Drugs
8
600-607
Recent progress in the development of inhibitors of the hepatitis C virus RNA-dependent RNA polymerase
2007
Koch, U.; Narjes, F.
Curr. Top. Med. Chem.
7
1302-1329
A single Gly114Arg mutation stabilizes the hexameric subunit assembly and changes the substrate specificity of halo-archaeal nucleoside diphosphate kinase
2007
Ishibashi, M.; Tatsuda, S.; Izutsu, K.; Kumeda, K.; Arakawa, T.; Tokunaga, M.
FEBS Lett.
581
4073-4079
Transient state kinetics of transcription elongation by T7 RNA polymerase
2006
Anand, V.S.; Patel, S.S.
J. Biol. Chem.
281
35677-35685
Identification of in vivo phosphorylation sites on human deoxycytidine kinase. Role of Ser-74 in the control of enzyme activity
2006
Smal, C.; Vertommen, D.; Bertrand, L.; Ntamashimikiro, S.; Rider, M.H.; Van Den Neste, E.; Bontemps, F.
J. Biol. Chem.
281
4887-4893
Kinetic analysis of the entire RNA amplification process by Qbeta replicase
2007
Hosoda, K.; Matsuura, T.; Kita, H.; Ichihashi, N.; Tsukada, K.; Yomo, T.
J. Biol. Chem.
282
15516-15527
Characterization of norovirus 3Dpol RNA-dependent RNA polymerase activity and initiation of RNA synthesis
2006
Rohayem, J.; Jaeger, K.; Robel, I.; Scheffler, U.; Temme, A.; Rudolph, W.
J. Gen. Virol.
87
2621-2630
Mechanism for de novo RNA synthesis and initiating nucleotide specificity by T7 RNA polymerase
2007
Kennedy, W.P.; Momand, J.R.; Yin, Y.W.
J. Mol. Biol.
370
256-268
Pharmacogenetics of deoxycytidine kinase: Identification and characterization of novel genetic variants
2007
Lamba, J.K.; Crews, K.; Pounds, S.; Schuetz, E.; Gresham, J.; Gandhi, V.; Plunkett, W.; Rubnitz, J.; Ribeiro, R.
J. Pharmacol. Exp. Ther.
323
935-945
Structural and functional characterization of sapovirus RNA-dependent RNA polymerase
2007
Fullerton, S.W.; Blaschke, M.; Coutard, B.; Gebhardt, J.; Gorbalenya, A.; Canard, B.; Tucker, P.A.; Rohayem, J.
J. Virol.
81
1858-1871
Crystal structure of poliovirus 3CD protein: virally encoded protease and precursor to the RNA-dependent RNA polymerase
2007
Marcotte, L.L.; Wass, A.B.; Gohara, D.W.; Pathak, H.B.; Arnold, J.J.; Filman, D.J.; Cameron, C.E.; Hogle, J.M.
J. Virol.
81
3583-3596
Crystal structure of the Dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-Angstrom resolution
2007
Yap, T.L.; Xu, T.; Chen, Y.L.; Malet, H.; Egloff, M.P.; Canard, B.; Vasudevan, S.G.; Lescar, J.
J. Virol.
81
4753-4765
Cloning and functional characterization of an O-acetylserine(thiol)lyase-encoding gene in wild soybean (Glycine soja)
2008
Zhang, C.; Meng, Q.; Gai, J.; Yu, D.
Mol. Biol. Rep.
35
527-534
The mechanism of DNA replication primer synthesis by RNA polymerase
2006
Zenkin, N.; Naryshkina, T.; Kuznedelov, K.; Severinov, K.
Nature
439
617-620
Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase
2007
Sabini, E.; Hazra, S.; Konrad, M.; Burley, S.K.; Lavie, A.
Nucleic Acids Res.
35
186-192
Enhanced activity of deoxycytidine kinase after pulsed low dose rate and single dose gamma irradiation
2006
Sigmond, J.; Haveman, J.; Kreder, N.C.; Loves, W.J.; van Bree, C.; Franken, N.A.; Peters, G.J.
Nucleosides Nucleotides Nucleic Acids
25
1177-1180
Cell cycle dependent regulation of deoxycytidine kinase, deoxyguanosine kinase, and cytosolic 5-nucleotidase I activity in MOLT-4 cells
2006
Fyrberg, A.; Mirzaee, S.; Lotfi, K.
Nucleosides Nucleotides Nucleic Acids
25
1201-1204
Two proton transfers in the transition state for nucleotidyl transfer catalyzed by RNA- and DNA-dependent RNA and DNA polymerases
2007
Castro, C.; Smidansky, E.; Maksimchuk, K.R.; Arnold, J.J.; Korneeva, V.S.; Goette, M.; Konigsberg, W.; Cameron, C.E.
Proc. Natl. Acad. Sci. USA
104
4267-4272
Biochemical characterization of the fidelity of poliovirus RNA-dependent RNA polymerase
2007
Freistadt, M.S.; Vaccaro, J.A.; Eberle, K.E.
Virol. J.
4
44
The human RNA polymerase II interacts with the terminal stem-loop regions of the hepatitis delta virus RNA genome
2007
Greco-Stewart, V.S.; Miron, P.; Abrahem, A.; Pelchat, M.
Virology
357
68-78
Template requirements for recognition and copying by Sindbis virus RNA-dependent RNA polymerase
2007
Thal, M.A.; Wasik, B.R.; Posto, J.; Hardy, R.W.
Virology
358
221-232
Inter-subunit interactions of the Autographa californica M nucleopolyhedrovirus RNA polymerase
2007
Crouch, E.A.; Cox, L.T.; Morales, K.G.; Passarelli, A.L.
Virology
367
265-274
Recruitment of RNA polymerase is a rate-limiting step for the activation of the sigma(54) promoter Pu of Pseudomonas putida
1999
Carmona, M.; de Lorenzo, V.; Bertoni, G.
J. Biol. Chem.
274
33790-33794
Phase I and pharmacokinetic study of triapine, a potent ribonucleotide reductase inhibitor, in adults with advanced hematologic malignancies
2007
Gojo, I.; Tidwell, M.L.; Greer, J.; Takebe, N.; Seiter, K.; Pochron, M.F.; Johnson, B.; Sznol, M.; Karp, J.E.
Leuk. Res.
31
1165-1173
Functional role of conserved residues in the characteristic secretion NTPase motifs of the Pseudomonas aeruginosa type IV pilus motor proteins PilB, PilT and PilU
2008
Chiang, P.; Sampaleanu, L.M.; Ayers, M.; Pahuta, M.; Howell, P.L.; Burrows, L.L.
Microbiology
154
114-126
A multi-step strategy to obtain crystals of the dengue virus RNA-dependent RNA polymerase that diffract to high resolution
2007
Yap, T.L.; Chen, Y.L.; Xu, T.; Wen, D.; Vasudevan, S.G.; Lescar, J.
Acta Crystallogr. Sect. F
F63
78-83
Nonnucleoside inhibitor of measles virus RNA-dependent RNA polymerase complex activity
2007
White, L.K.; Yoon, J.J.; Lee, J.K.; Sun, A.; Du, Y.; Fu, H.; Snyder, J.P.; Plemper, R.K.
Antimicrob. Agents Chemother.
51
2293-2303
The mechanism of action of beta-D-2-deoxy-2-fluoro-2-C-methylcytidine involves a second metabolic pathway leading to beta-D-2-deoxy-2-fluoro-2-C-methyluridine 5-triphosphate, a potent inhibitor of the hepatitis C virus RNA-dependent RNA polymerase
2008
Murakami, E.; Niu, C.; Bao, H.; Micolochick Steuer, H.M.; Whitaker, T.; Nachman, T.; Sofia, M.A.; Wang, P.; Otto, M.J.; Furman, P.A.
Antimicrob. Agents Chemother.
52
458-464
In vitro resistance study of AG-021541, a novel nonnucleoside inhibitor of the hepatitis C virus RNA-dependent RNA polymerase
2008
Shi, S.T.; Herlihy, K.J.; Graham, J.P.; Fuhrman, S.A.; Doan, C.; Parge, H.; Hickey, M.; Gao, J.; Yu, X.; Chau, F.; Gonzalez, J.; Li, H.; Lewis, C.; Patick, A.K.; Duggal, R.
Antimicrob. Agents Chemother.
52
675-683
Effective inhibition of porcine transmissible gastroenteritis virus replication in ST cells by shRNAs targeting RNA-dependent RNA polymerase gene
2007
Zhou, J.F.; Hua, X.G.; Cui, L.; Zhu, J.G.; Miao, D.N.; Zou, Y.; He, X.Z.; Su, W.G.
Antiviral Res.
74
36-42
Identification and characterization of mutations conferring resistance to an HCV RNA-dependent RNA polymerase inhibitor in vitro
2007
Lu, L.; Dekhtyar, T.; Masse, S.; Pithawalla, R.; Krishnan, P.; He, W.; Ng, T.; Koev, G.; Stewart, K.; Larson, D.; Bosse, T.; Wagner, R.; Pilot-Matias, T.; Mo, H.; Molla, A.
Antiviral Res.
76
93-97
RNA template-mediated inhibition of hepatitis C virus RNA-dependent RNA polymerase activity
2008
Wang, Y.K.; Rigat, K.L.; Sun, J.H.; Gao, M.; Roberts, S.B.
Arch. Biochem. Biophys.
470
146-152
Molecular cloning and analysis of function of nucleoside diphosphate kinase (NDPK) from the scallop Chlamys farreri
2008
Shi, X.Z.; Zhao, X.F.; Wang, J.X.
Biochemistry (Moscow)
73
686-692
Studies on acyl pyrrolidine inhibitors of HCV RNA-dependent RNA polymerase to identify a molecule with replicon antiviral activity
2007
Burton, G.; Ku, T.W.; Carr, T.J.; Kiesow, T.; Sarisky, R.T.; Lin-Goerke, J.; Hofmann, G.A.; Slater, M.J.; Haigh, D.; Dhanak, D.; Johnson, V.K.; Parry, N.R.; Thommes, P.
Bioorg. Med. Chem. Lett.
17
1930-1933
Further studies on hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors toward improved replicon cell activities: benzimidazole and structurally related compounds bearing the 2-morpholinophenyl moiety
2007
Hirashima, S.; Oka, T.; Ikegashira, K.; Noji, S.; Yamanaka, H.; Hara, Y.; Goto, H.; Mizojiri, R.; Niwa, Y.; Noguchi, T.; Ando, I.; Ikeda, S.; Hashimoto, H.
Bioorg. Med. Chem. Lett.
17
3181-3186
Non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex activity: Synthesis and in vitro evaluation
2007
Sun, A.; Chandrakumar, N.; Yoon, J.J.; Plemper, R.K.; Snyder, J.P.
Bioorg. Med. Chem. Lett.
17
5199-5203
Des-A-ring benzothiadiazines: inhibitors of HCV genotype 1 NS5B RNA-dependent RNA polymerase
2008
Donner, P.L.; Xie, Q.; Pratt, J.K.; Maring, C.J.; Kati, W.; Jiang, W.; Liu, Y.; Koev, G.; Masse, S.; Montgomery, D.; Molla, A.; Kempf, D.J.
Bioorg. Med. Chem. Lett.
18
2735-2738
The transcription reinitiation properties of RNA polymerase III in the absence of transcription factors
2008
Ferrari, R.; Dieci, G.
Cell. Mol. Biol. Lett.
13
112-118
Physicochemical properties of the nucleoside prodrug R1626 leading to high oral bioavailability
2008
Brandl, M.; Wu, X.; Holper, M.; Hong, L.; Jia, Z.; Birudaraj, R.; Reddy, M.; Alfredson, T.; Tran, T.; Larrabee, S.; Hadig, X.; Sarma, K.; Washington, C.; Hill, G.; Smith, D.B.
Drug Dev. Ind. Pharm.
34
683-691
Trypanosoma cruzi: multiple nucleoside diphosphate kinase isoforms in a single cell
2008
Miranda, M.R.; Canepa, G.E.; Bouvier, L.A.; Pereira, C.A.
Exp. Parasitol.
120
103-107
Inhibition of HIV-1 replication with designed miRNAs expressed from RNA polymerase II promoters
2007
Lo, H.; Chang, T.; Yam, P.; Marcovecchio, P.M.; Li, S.; Zaia, J.A.; Yee, J.
Gene Ther.
14
1503-1512
Host factor Ebp1: selective inhibitor of influenza virus transcriptase
2007
Honda, A.; Okamoto, T.; Ishihama, A.
Genes Cells
12
133-142
Characterization of the RNA polymerase II and III complexes in Leishmania major
2007
Martinez-Calvillo, S.; Saxena, A.; Green, A.; Leland, A.; Myler, P.J.
Int. J. Parasitol.
37
491-502
Functional characterization of fingers subdomain-specific monoclonal antibodies inhibiting the hepatitis C virus RNA-dependent RNA polymerase
2008
Nikonov, A.; Juronen, E.; Ustav, M.
J. Biol. Chem.
283
24089-24102
Optimization of novel acyl pyrrolidine inhibitors of hepatitis C virus RNA-dependent RNA polymerase leading to a development candidate
2007
Slater, M.J.; Amphlett, E.M.; Andrews, D.M.; Bravi, G.; Burton, G.; Cheasty, A.G.; Corfield, J.A.; Ellis, M.R.; Fenwick, R.H.; Fernandes, S.; Guidetti, R.; Haigh, D.; Hartley, C.D.; Howes, P.D.; Jackson, D.L.; Jarvest, R.L.; Lovegrove, V.L.; Medhurst, K.J.; Parry, N.R.; Price, H.; Shah, P.; Singh, O.M.; Stocker, R.
J. Med. Chem.
50
897-900
Potent non-nucleoside inhibitors of the measles virus RNA-dependent RNA polymerase complex
2008
Sun, A.; Yoon, J.J.; Yin, Y.; Prussia, A.; Yang, Y.; Min, J.; Plemper, R.K.; Snyder, J.P.
J. Med. Chem.
51
3731-3741
The imidazopyrrolopyridine analogue AG110 is a novel, highly selective inhibitor of pestiviruses that targets the viral RNA-dependent RNA polymerase at a hot spot for inhibition of viral replication
2007
Paeshuyse, J.; Chezal, J.M.; Froeyen, M.; Leyssen, P.; Dutartre, H.; Vrancken, R.; Canard, B.; Letellier, C.; Li, T.; Mittendorfer, H.; Koenen, F.; Kerkhofs, P.; De Clercq, E.; Herdewijn, P.; Puerstinger, G.; Gueiffier, A.; Chavignon, O.; Teulade, J.C.; Neyts, J.
J. Virol.
81
11046-11053
Characterization of protein-protein interactions critical for poliovirus replication: analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase
2007
Strauss, D.M.; Wuttke, D.S.
J. Virol.
81
6369-6378
Determinants of RNA-dependent RNA polymerase (in)fidelity revealed by kinetic analysis of the polymerase encoded by a foot-and-mouth disease virus mutant with reduced sensitivity to ribavirin
2008
Arias, A.; Arnold, J.J.; Sierra, M.; Smidansky, E.; Domingo, E.; Cameron, C.E.
J. Virol.
82
12346-12355
The crystal structure of coxsackievirus B3 RNA-dependent RNA polymerase in complex with its protein primer VPg confirms the existence of a second VPg binding site on Picornaviridae polymerases
2008
Gruez, A.; Selisko, B.; Roberts, M.; Bricogne, G.; Bussetta, C.; Jabafi, I.; Coutard, B.; De Palma, A.M.; Neyts, J.; Canard, B.
J. Virol.
82
9577-9590
Molecular cloning and characterization of an inducible RNA-dependent RNA polymerase gene, GhRdRP, from cotton (Gossypium hirsutum L.)
2007
Gao, Q.; Liu, Y.; Wang, M.; Zhang, J.; Gai, Y.; Zhu, C.; Guo, X.
Mol. Biol. Rep.
36
47-56
Structural basis of transcription inhibition by alpha-amanitin and implications for RNA polymerase II translocation
2008
Brueckner, F.; Cramer, P.
Nat. Struct. Mol. Biol.
15
811-818
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks
2007
Kruhlak, M.; Crouch, E.E.; Orlov, M.; Montano, C.; Gorski, S.A.; Nussenzweig, A.; Misteli, T.; Phair, R.D.; Casellas, R.
Nature
447
730-734
The X-ray crystal structure of RNA polymerase from Archaea
2008
Hirata, A.; Klein, B.J.; Murakami, K.S.
Nature
451
851-854
Function and assembly of a chromatin-associated RNase P that is required for efficient transcription by RNA polymerase I
2008
Reiner, R.; Krasnov-Yoeli, N.; Dehtiar, Y.; Jarrous, N.
PLoS ONE
3
e4072
Inhibition of HCV RNA-dependent RNA polymerase activity by aqueous extract from Fructus Ligustri Lucidi
2007
Kong, L.; Li, S.; Han, X.; Xiang, Z.; Fang, X.; Li, B.; Wang, W.; Zhong, H.; Gao, J.; Ye, L.
Virus Res.
128
9-17
Structure-function studies of the RNA polymerase II elongation complex
2009
Brueckner, F.; Armache, K.J.; Cheung, A.; Damsma, G.E.; Kettenberger, H.; Lehmann, E.; Sydow, J.; Cramer, P.
Acta Crystallogr. Sect. D
65
112-120
The RNA polymerase I transcription machinery: an emerging target for the treatment of cancer
2010
Drygin, D.; Rice, W.G.; Grummt, I.
Annu. Rev. Pharmacol. Toxicol.
50
131-156
Positive modulation of RNA polymerase III transcription by ribosomal proteins
2009
Dieci, G.; Ruotolo, R.; Braglia, P.; Carles, C.; Carpentieri, A.; Amoresano, A.; Ottonello, S.
Biochem. Biophys. Res. Commun.
379
489-493
Biochemical and kinetic analysis of the influenza virus RNA polymerase purified from insect cells
2009
Zhang, S.; Weng, L.; Geng, L.; Wang, J.; Zhou, J.; Deubel, V.; Buchy, P.; Toyoda, T.
Biochem. Biophys. Res. Commun.
391
570-574
Remodeling and activation of Escherichia coli RNA polymerase by osmolytes
2008
Gralla, J.D.; Huo, Y.X.
Biochemistry
47
13189-13196
RNA polymerase - The third class of primases
2008
Zenkin, N.; Severinov, K.
Cell. Mol. Life Sci.
65
2280-2288
TFB2 is a transient component of the catalytic site of the human mitochondrial RNA polymerase
2009
Sologub, M.; Litonin, D.; Anikin, M.; Mustaev, A.; Temiakov, D.
Cell
139
934-944
RNA polymerases
2008
Paschal, B.M.; McReynolds, L.A.; Noren, C.J.; Nichols, N.M.
Curr. Protoc. Mol. Biol.
Chapter 3
Unit3.8
Modifications of RNA polymerase II are pivotal in regulating gene expression states
2009
Brookes, E.; Pombo, A.
EMBO Rep.
10
1213-1219
DNA conformation-dependent activities of human mitochondrial RNA polymerase
2009
Fukuoh, A.; Ohgaki, K.; Hatae, H.; Kuraoka, I.; Aoki, Y.; Uchiumi, T.; Jacobs, H.T.; Kang, D.
Genes Cells
14
1029-1042
Direct inhibition of RNA polymerase II transcription by RECQL5
2009
Ayguen, O.; Xu, X.; Liu, Y.; Takahashi, H.; Kong, S.E.; Conaway, R.C.; Conaway, J.W.; Svejstrup, J.Q.
J. Biol. Chem.
284
23197-23203
RNA polymerase II C-terminal heptarepeat domain Ser-7 phosphorylation is established in a mediator-dependent fashion
2010
Boeing, S.; Rigault, C.; Heidemann, M.; Eick, D.; Meisterernst, M.
J. Biol. Chem.
285
188-196
Site-specific cleavage of HCV genomic RNA and its cloned core and NS5B genes by DNAzyme
2009
Kumar, D.; Chaudhury, I.; Kar, P.; Das, R.H.
J. Gastroenterol. Hepatol.
24
872-878
Molecular characterization of a dual inhibitory and mutagenic activity of 5-fluorouridine triphosphate on viral RNA synthesis. Implications for lethal mutagenesis
2008
Agudo, R.; Arias, A.; Pariente, N.; Perales, C.; Escarmis, C.; Jorge, A.; Marina, A.; Domingo, E.
J. Mol. Biol.
382
652-666
Evidence for action of ribavirin through the hepatitis C virus RNA polymerase
2009
Cannon, N.A.; Donlin, M.J.; Mayes, L.M.; Lyra, A.C.; Di Bisceglie, A.M.; Tavis, J.E.
J. Viral Hepat.
16
595-604
RNA polymerase: a nexus of gene regulation
2009
Helmann, J.D.
Methods
47
1-5
Non-DNA-templated addition of nucleotides to the 3' end of RNAs by the mitochondrial RNA polymerase of Physarum polycephalum
2008
Miller, M.L.; Miller, D.L.
Mol. Cell. Biol.
28
5795-5802
TLS inhibits RNA polymerase III transcription
2010
Tan, A.Y.; Manley, J.L.
Mol. Cell. Biol.
30
186-196
The cap-snatching endonuclease of influenza virus polymerase resides in the PA subunit
2009
Dias, A.; Bouvier, D.; Crepin, T.; McCarthy, A.A.; Hart, D.J.; Baudin, F.; Cusack, S.; Ruigrok, R.W.
Nature
458
914-918
Insights into the pre-initiation events of bacteriophage phi 6 RNA-dependent RNA polymerase: towards the assembly of a productive binary complex
2009
Sarin, L.P.; Poranen, M.M.; Lehti, N.M.; Ravantti, J.J.; Koivunen, M.R.; Aalto, A.P.; van Dijk, A.A.; Stuart, D.I.; Grimes, J.M.; Bamford, D.H.
Nucleic Acids Res.
37
1182-1192
Repression of RNA polymerase II elongation in vivo is critically dependent on the C-terminus of Spt5
2009
Chen, H.; Contreras, X.; Yamaguchi, Y.; Handa, H.; Peterlin, B.M.; Guo, S.
PLoS ONE
4
e6918
A discontinuous RNA platform mediates RNA virus replication: building an integrated model for RNA-based regulation of viral processes
2009
Wu, B.; Pogany, J.; Na, H.; Nicholson, B.L.; Nagy, P.D.; White, K.A.
PLoS Pathog.
5
e1000323
Overproduction and purification of recombinant Bacillus subtilis RNA polymerase
2008
Yang, X.; Lewis, P.J.
Protein Expr. Purif.
59
86-93
Purification of RNA polymerase from mycobacteria for optimized promoter-polymerase interactions
2010
China, A.; Nagaraja, V.
Protein Expr. Purif.
69
235-242
Enzymatic and nonenzymatic functions of viral RNA-dependent RNA polymerases within oligomeric arrays
2010
Spagnolo, J.F.; Rossignol, E.; Bullitt, E.; Kirkegaard, K.
RNA
16
382-393
The use of thiols by ribonucleotide reductase
2010
Holmgren, A.; Sengupta, R.
Free Radic. Biol. Med.
49
1617-1628
Closing the circle on ribonucleotide reductases
2011
Logan, D.
Nat. Struct. Mol. Biol.
18
251-253
A novel type of replicative enzyme harbouring ATPase, primase and DNA polymerase activity
2003
Lipps, G.; Röther, S.; Hart, C.; Krauss, G.
EMBO J.
22
2516-2525
Molecular modeling and functional characterization of the monomeric primase-polymerase domain from the Sulfolobus solfataricus plasmid pIT3
2008
Prato, S.; Vitale, R.M.; Contursi, P.; Lipps, G.; Saviano, M.; Rossi, M.; Bartolucci, S.
FEBS J.
275
4389-4402
Cleavage of double-stranded DNA by the intrinsic 3-5 exonuclease activity of DNA polymerase B1 from the hyperthermophilic archaeon Sulfolobus solfataricus at high temperature
2004
Lou, H.; Duan, Z.; Sun, T.; Huang, L.
FEMS Microbiol. Lett.
231
111-117
The archaeal DNA primase: biochemical characterization of the p41-p46 complex from Pyrococcus furiosus
2001
Liu, L.; Komori, K.; Ishino, S.; Bocquier, A.A.; Cann, I.K.; Kohda, D.; Ishino, Y.
J. Biol. Chem.
276
45484-45490
Characterization of DNA primase complex isolated from the archaeon, Thermococcus kodakaraensis
2012
Chemnitz Galal, W.; Pan, M.; Kelman, Z.; Hurwitz, J.
J. Biol. Chem.
287
16209-16219
The heterodimeric primase of the hyperthermophilic archaeon Sulfolobus solfataricus possesses DNA and RNA primase, polymerase and 3-terminal nucleotidyl transferase activities
2004
Lao-Sirieix, S.H.; Bell, S.D.
J. Mol. Biol.
344
1251-1263
The heterodimeric primase from the euryarchaeon Pyrococcus abyssi: a multifunctional enzyme for initiation and repair?
2007
Le Breton, M.; Henneke, G.; Norais, C.; Flament, D.; Myllykallio, H.; Querellou, J.; Raffin, J.P.
J. Mol. Biol.
374
1172-1185
Characterization of a functional DnaG-type primase in archaea: implications for a dual-primase system
2010
Zuo, Z.; Rodgers, C.J.; Mikheikin, A.L.;, Trakselis, M.A.
J. Mol. Biol.
397
664-676
Interplay between primase and replication factor C in the hyperthermophilic archaeon Sulfolobus solfataricus
2006
Wu, K.; Lai, X.; Guo, X.; Hu, J.; Xiang, X.; Huang, L.
Mol. Microbiol.
63
826-837
Identification and characterization of a DNA primase from the hyperthermophilic archaeon Methanococcus jannaschii
1999
Desogus, G.; Onesti, S.; Brick, P.; Rossi, M.; Pisani, F.M.
Nucleic Acids Res.
27
4444-4450
The DNA primase of Sulfolobus solfataricus is activated by substrates containing a thymine-rich bubble and has a 3'-terminal nucleotidyl-transferase activity
2004
De Falco, M.; Fusco, A.; De Felice, M.; Rossi, M.; Pisani, F.M.
Nucleic Acids Res.
32
5223-5230
Properties of an unusual DNA primase from an archaeal plasmid
2007
Beck, K.; Lipps, G.
Nucleic Acids Res.
35
5635-5645
Template-dependent polymerization across discontinuous templates by the heterodimeric primase from the hyperthermophilic archaeon Sulfolobus solfataricus
2012
Hu, J.; Guo, L.; Wu, K.; Liu, B.; Lang, S.; Huang, L.
Nucleic Acids Res.
40
3470-3483
Application of Escherichia coli phage K1E DNA-dependent RNA polymerase for in vitro RNA synthesis and in vivo protein production in Bacillus megaterium
2010
Stammen, S.; Schuller, F.; Dietrich, S.; Gamer, M.; Biedendieck, R.; Jahn, D.
Appl. Microbiol. Biotechnol.
88
529-539
Human mitochondrial RNA polymerase: structure-function, mechanism and inhibition
2012
Arnold, J.J.; Smidansky, E.D.; Moustafa, I.M.; Cameron, C.E.
Biochim. Biophys. Acta
1819
948-960
The human 2'-5' oligoadenylate synthetase family: unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation
2007
Hovanessian, A.; Justesen, J.
Biochimie
89
779-788
Expression and characterization of RNA-dependent RNA polymerase of Ectropis obliqua virus
2010
Lin, M.; Ye, S.; Xiong, Y.; Cai, D.; Zhang, J.; Hu, Y.
BMB Rep.
43
284-290
Hypoxia-induced deoxycytidine kinase expression contributes to apoptosis in chronic lung disease
2013
Weng, T.; Karmouty-Quintana, H.; Garcia-Morales, L.J.; Molina, J.G.; Pedroza, M.; Bunge, R.R.; Bruckner, B.A.; Loebe, M.; Seethamraju, H.; Blackburn, M.R.
FASEB J.
27
2013-2026
Requirement for deoxycytidine kinase in T and B lymphocyte development
2010
Toy, G.; Austin, W.R.; Liao, H.I.; Cheng, D.; Singh, A.; Campbell, D.O.; Ishikawa, T.O.; Lehmann, L.W.; Satyamurthy, N.; Phelps, M.E.; Herschman, H.R.; Czernin, J.; Witte, O.N.; Radu, C.G.
Proc. Natl. Acad. Sci. USA
107
5551-5556
DNA-dependent RNA polymerase of thermoacidophilic archaebacteria
1982
Prangishvilli, D.; Zillig, W.; Gierl, A.; Biesert, L.; Holz, I.
Eur. J. Biochem.
122
471-477
Archaebacterial DNA-dependent RNA polymerases testify to the evolution of the eukaryotic nuclear genome
1989
Pühler, G.; Leffers, H.; Gropp, F.; Palm, P.; Klenk, H.P.; Lottspeich, F.; Garrett, R.A.; Zillig, W.
Proc. Natl. Acad. Sci. USA
86
4569-4573
Expression, crystallization and preliminary X-ray crystallographic analysis of DNA-directed RNA polymerase subunit L from Thermococcus onnurineus NA1
2014
Ho, T.H.; Hong, M.K.; Ngo, H.P.; Kang, L.W.
Acta Crystallogr. Sect. F
70
639-642
Novel 4-thiazolidinones as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase
2015
Cakir, G.; Kuecuekguezel, I.; Guhamazumder, R.; Tatar, E.; Manvar, D.; Basu, A.; Patel, B.A.; Zia, J.; Talele, T.T.; Kaushik-Basu, N.
Arch. Pharm.
348
10-22
-
Modified in vivo subunits of DNA-dependent RNA polymerase III in mammals
2015
Merkulova, N.; Sedova, V.
Cell Tissue Biol.
9
284-289
RNA polymerase II acts as an RNA-dependent RNA polymerase to extend and destabilize a non-coding RNA
2013
Wagner, S.D.; Yakovchuk, P.; Gilman, B.; Ponicsan, S.L.; Drullinger, L.F.; Kugel, J.F.; Goodrich, J.A.
EMBO J.
32
781-790
Melatonin overcomes resistance to clofarabine in two leukemic cell lines by increased expression of deoxycytidine kinase
2015
Yamanishi, M.; Narazaki, H.; Asano, T.
Exp. Hematol.
43
207-214
Hydrogen/deuterium exchange kinetics demonstrate long range allosteric effects of thumb site 2 inhibitors of hepatitis C viral RNA-dependent RNA polymerase
2016
Deredge, D.; Li, J.; Johnson, K.A.; Wintrode, P.L.
J. Biol. Chem.
291
10078-10088
The yeast mitochondrial RNA polymerase and transcription factor complex catalyzes efficient priming of DNA synthesis on single-stranded DNA
2016
Ramachandran, A.; Nandakumar, D.; Deshpande, A.P.; Lucas, T.P.; R-Bhojappa, R.; Tang, G.Q.; Raney, K.; Yin, Y.W.; Patel, S.S.
J. Biol. Chem.
291
16828-16839
Reconstitution of the RNA-dependent RNA polymerase activity of Antheraea mylitta cypovirus in vitro using separately expressed different functional domains of the enzyme
2016
Kundu, A.; Roychowdhury, A.; Bose, M.; Das, A.K.; Ghosh, A.K.
J. Gen. Virol.
97
1709-1719
Role of motif B loop in allosteric regulation of RNA-dependent RNA polymerization activity
2013
Garriga, D.; Ferrer-Orta, C.; Querol-Audi, J.; Oliva, B.; Verdaguer, N.
J. Mol. Biol.
425
2279-2287
-
Expression and enzymatic activity analysis of deoxycytidine kinase in silk worm larvae using dual promoters BmNPV/Bac-to-Bac system
2014
Gao, J.; Zhang, Y.; Wan, X.; Yang, X.; Yu, H.; Xu, J.
J. Pure Appl. Microbiol.
8
1837-1844
A primase subunit essential for efficient primer synthesis by an archaeal eukaryotic-type primase
2015
Liu, B.; Ouyang, S.; Makarova, K.S.; Xia, Q.; Zhu, Y.; Li, Z.; Guo, L.; Koonin, E.V.; Liu, Z.J.; Huang, L.
Nat. Commun.
6
7300
Crystal structure of the RNA-dependent RNA polymerase from influenza C virus
2015
Hengrung, N.; El Omari, K.; Serna Martin, I.; Vreede, F.T.; Cusack, S.; Rambo, R.P.; Vonrhein, C.; Bricogne, G.; Stuart, D.I.; Grimes, J.M.; Fodor, E.
Nature
527
114-117
RNA-dependent RNA polymerase of Japanese encephalitis virus binds the initiator nucleotide GTP to form a mechanistically important pre-initiation state
2014
Surana, P.; Satchidanandam, V.; Nair, D.T.
Nucleic Acids Res.
42
2758-2773
The Dictyostelium discoideum RNA-dependent RNA polymerase RrpC silences the centromeric retrotransposon DIRS-1 post-transcriptionally and is required for the spreading of RNA silencing signals
2014
Wiegand, S.; Meier, D.; Seehafer, C.; Malicki, M.; Hofmann, P.; Schmith, A.; Winckler, T.; Foeldesi, B.; Boesler, B.; Nellen, W.; Reimegard, J.; Kaeller, M.; Haellman, J.; Emanuelsson, O.; Avesson, L.; Soederbom, F.; Hammann, C.
Nucleic Acids Res.
42
3330-3345
Potent sensitisation of cancer cells to anticancer drugs by a quadruple mutant of the human deoxycytidine kinase
2015
Coulibaly, S.T.; Rossolillo, P.; Winter, F.; Kretzschmar, F.K.; Braye, M.; Martin, D.P.; Lener, D.; Negroni, M.
PLoS ONE
10
e0140741
Characterization of soluble RNA-dependent RNA polymerase from dengue virus serotype 2: The polyhistidine tag compromises the polymerase activity
2015
Kamkaew, M.; Chimnaronk, S.
Protein Expr. Purif.
112
43-49
Structure of the RNA-directed RNA polymerase from the cystovirus phi12
2013
Ren, Z.; C Franklin, M.; Ghose, R.
Proteins
81
1479-1484
RNA-dependent RNA polymerase 1 in potato (Solanum tuberosum) and its relationship to other plant RNA-dependent RNA polymerases
2016
Hunter, L.J.; Brockington, S.F.; Murphy, A.M.; Pate, A.E.; Gruden, K.; MacFarlane, S.A.; Palukaitis, P.; Carr, J.P.
Sci. Rep.
6
23082
Purification and biochemical characterisation of rabbit calicivirus RNA-dependent RNA polymerases and identification of non-nucleoside inhibitors
2016
Urakova, N.; Netzler, N.; Kelly, A.G.; Frese, M.; White, P.A.; Strive, T.
Viruses
8
100
-
N-acetylglucosamine 2-epimerase from Pedobacter heparinus First experimental evidence of a deprotonation/reprotonation mechanism
2016
Wang, S.; Laborda, P.; Lu, A.; Duan, X.; Ma, H.; Liu, L.; Voglmeir, J.
Catalysts
6
212-228
Primase, the dnaG protein of Escherichia coli. An enzyme which starts DNA chains
1978
Rowen, L.; Kornberg, A.
J. Biol. Chem.
253
758-764
The heterodimeric primase from the euryarchaeon Pyrococcus abyssi a multifunctional enzyme for initiation and repair?
2007
Le Breton, M.; Henneke, G.; Norais, C.; Flament, D.; Myllykallio, H.; Querellou, J.; Raffin, J.
J. Mol. Biol.
374
1172-1185
Characterization of a functional DnaG-type primase in archaea implications for a dual-primase system
2010
Zuo, Z.; Rodgers, C.J.; Mikheikin, A.L.; Trakselis, M.A.
J. Mol. Biol.
397
664-676
Biochemical characterization of respiratory syncytial virus RNA-dependent RNA polymerase complex
2020
Balakrishnan, A.; Price, E.; Luu, C.; Shaul, J.; Wartchow, C.; Cantwell, J.; Vo, T.; DiDonato, M.; Spraggon, G.; Hekmat-Nejad, M.
ACS Infect. Dis.
6
2800-2811
Prediction of small molecule inhibitors targeting the severe acute respiratory syndrome coronavirus-2 RNA-dependent RNA polymerase
2020
Ahmad, M.; Dwivedy, A.; Mariadasse, R.; Tiwari, S.; Kar, D.; Jeyakanthan, J.; Biswal, B.K.
ACS Omega
5
18356-18366
Analysis of ribonucleotide 5-triphosphate analogs as potential inhibitors of Zika Virus RNA-dependent RNA polymerase by using nonradioactive polymerase assays
2017
Lu, G.; Bluemling, G.R.; Collop, P.; Hager, M.; Kuiper, D.; Gurale, B.P.; Painter, G.R.; De La Rosa, A.; Kolykhalov, A.A.
Antimicrob. Agents Chemother.
61
e01967-16
RNA-dependent RNA polymerase Structure, mechanism, and drug discovery for COVID-19
2020
Jiang, Y.; Yin, W.; Xu, H.E.
Biochem. Biophys. Res. Commun.
538
47-53
Structure-activity relationship of uridine-based nucleoside phosphoramidate prodrugs for inhibition of dengue virus RNA-dependent RNA polymerase
2018
Wang, G.; Lim, S.P.; Chen, Y.L.; Hunziker, J.; Rao, R.; Gu, F.; Seh, C.C.; Ghafar, N.A.; Xu, H.; Chan, K.; Lin, X.; Saunders, O.L.; Fenaux, M.; Zhong, W.; Shi, P.Y.; Yokokawa, F.
Bioorg. Med. Chem. Lett.
28
2324-2327
Structural basis for RNA replication by the SARS-CoV-2 polymerase
2020
Wang, Q.; Wu, J.; Wang, H.; Gao, Y.; Liu, Q.; Mu, A.; Ji, W.; Yan, L.; Zhu, Y.; Zhu, C.; Fang, X.; Yang, X.; Huang, Y.; Gao, H.; Liu, F.; Ge, J.; Sun, Q.; Yang, X.; Xu, W.; Liu, Z.; Yang, H.; Lou, Z.; Jiang, B.; Guddat, L.W.; Gong, P.; Rao, Z.
Cell
182
417-428.e13
Structural and biochemical characterization of the nsp12-nsp7-nsp8 core polymerase complex from SARS-CoV-2
2020
Peng, Q.; Peng, R.; Yuan, B.; Zhao, J.; Wang, M.; Wang, X.; Wang, Q.; Sun, Y.; Fan, Z.; Qi, J.; Gao, G.F.; Shi, Y.
Cell Rep.
31
107774
Mechanistic insight on the remdesivir binding to RNA-dependent RNA polymerase (RdRp) of SARS-cov-2
2020
Arba, M.; Wahyudi, S.T.; Brunt, D.J.; Paradis, N.; Wu, C.
Comput. Biol. Med.
129
104156
The binding of remdesivir to SARS-CoV-2 RNA-dependent RNA polymerase may pave the way towards the design of potential drugs for COVID-19 treatment
2020
Agoni, C.; Soliman, M.E.S.
Curr. Pharm. Biotechnol.
22
1520-1537
Flavonols as potential antiviral drugs targeting SARS-CoV-2 proteases (3CLpro and PLpro), spike protein, RNA-dependent RNA polymerase (RdRp) and angiotensin-converting enzyme II receptor (ACE2)
2020
Mouffouk, C.; Mouffouk, S.; Mouffouk, S.; Hambaba, L.; Haba, H.
Eur. J. Pharmacol.
891
173759
Targeting SARS-CoV-2 RNA-dependent RNA polymerase An in silico drug repurposing for COVID-19
2020
Baby, K.; Maity, S.; Mehta, C.H.; Suresh, A.; Nayak, U.Y.; Nayak, Y.
F1000Res.
9
1166
Identification of potential key agents for targeting RNA-dependent RNA polymerase of SARS-CoV-2 by integrated analysis and virtual drug screening
2020
Ao, S.; Han, D.; Sun, L.; Wu, Y.; Liu, S.; Huang, Y.
Front. Genet.
11
581668
Calicivirus RNA-dependent RNA polymerases Evolution, structure, protein dynamics, and function
2019
Smertina, E.; Urakova, N.; Strive, T.; Frese, M.
Front. Microbiol.
10
1280
RNA-dependent RNA polymerase speed and fidelity are not the only determinants of the mechanism or efficiency of recombination
2019
Kim, H.; Ellis, V.D.; Woodman, A.; Zhao, Y.; Arnold, J.J.; Cameron, C.E.
Genes (Basel)
10
968
Prediction of potential inhibitors for RNA-dependent RNA polymerase of SARS-CoV-2 using comprehensive drug repurposing and molecular docking approach
2020
Parvez, M.S.A.; Karim, M.A.; Hasan, M.; Jaman, J.; Karim, Z.; Tahsin, T.; Hasan, M.N.; Hosen, M.J.
Int. J. Biol. Macromol.
163
1787-1797
Zinc and SARS-CoV-2 A molecular modeling study of Zn interactions with RNA-dependent RNA-polymerase and 3C-like proteinase enzymes
2021
Pormohammad, A.; Monych, N.K.; Turner, R.J.
Int. J. Mol. Med.
47
326-334
Remdesivir is effective in combating COVID-19 because it is a better substrate than ATP for the viral RNA-dependent RNA polymerase
2020
Dangerfield, T.L.; Huang, N.Z.; Johnson, K.A.
iScience
23
101849
Purification of Zika virus RNA-dependent RNA polymerase and its use to identify small-molecule Zika inhibitors
2017
Xu, H.T.; Hassounah, S.A.; Colby-Germinario, S.P.; Oliveira, M.; Fogarty, C.; Quan, Y.; Han, Y.; Golubkov, O.; Ibanescu, I.; Brenner, B.; Stranix, B.R.; Wainberg, M.A.
J. Antimicrob. Chemother.
72
727-734
The hepatitis C virus RNA-dependent RNA polymerase directs incoming nucleotides to its active site through magnesium-dependent dynamics within its F motif
2019
Ben Ouirane, K.; Boulard, Y.; Bressanelli, S.
J. Biol. Chem.
294
7573-7587
Development of remdesivir repositioning as a nucleotide analog against COVID-19 RNA dependent RNA polymerase
2020
Babadaei, M.M.N.; Hasan, A.; Vahdani, Y.; Bloukh, S.H.; Sharifi, M.; Kachooei, E.; Haghighat, S.; Falahati, M.
J. Biomol. Struct. Dyn.
2020
1-9
Insights into structural dynamics of allosteric binding sites in HCV RNA-dependent RNA polymerase
2020
Mittal, L.; Kumari, A.; Suri, C.; Bhattacharya, S.; Asthana, S.
J. Biomol. Struct. Dyn.
38
1612-1625
In silico identification of widely used and well-tolerated drugs as potential SARS-CoV-2 3C-like protease and viral RNA-dependent RNA polymerase inhibitors for direct use in clinical trials
2020
Gul, S.; Ozcan, O.; Asar, S.; Okyar, A.; Baris, I.; Kavakli, I.H.
J. Biomol. Struct. Dyn.
39
6772-6791
Pharmacological therapeutics targeting RNA-dependent RNA polymerase, proteinase and spike protein from mechanistic studies to clinical trials for COVID-19
2020
Huang, J.; Song, W.; Huang, H.; Sun, Q.
J. Clin. Med.
9
1131
Potential RNA-dependent RNA polymerase inhibitors as prospective therapeutics against SARS-CoV-2
2020
Pokhrel, R.; Chapagain, P.; Siltberg-Liberles, J.
J. Med. Microbiol.
69
864-873
Effects of mutations on active site conformation and dynamics of RNA-dependent RNA polymerase from Coxsackievirus B3
2017
Shen, H.; Deng, M.; Zhang, Y.
J. Mol. Graph. Model.
77
330-337
Nucleotide analogues as inhibitors of SARS-CoV-2 polymerase, a key drug target for COVID-19
2020
Chien, M.; Anderson, T.K.; Jockusch, S.; Tao, C.; Li, X.; Kumar, S.; Russo, J.J.; Kirchdoerfer, R.N.; Ju, J.
J. Proteome Res.
19
4690-4697
Structural insights into the binding modes of viral RNA-dependent RNA polymerases using a function-site interaction fingerprint method for RNA virus drug discovery
2020
Zhao, Z.; Bourne, P.E.
J. Proteome Res.
19
4698-4705
Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel
2020
Li, L.; Wang, M.; Chen, Y.; Hu, T.; Yang, Y.; Zhang, Y.; Bi, G.; Wang, W.; Liu, E.; Han, J.; Lu, T.; Su, D.
J. Struct. Biol.
211
107510
SARS-CoV-2 RNA polymerase as target for antiviral therapy
2020
Buonaguro, L.; Tagliamonte, M.; Tornesello, M.L.; Buonaguro, F.M.
J. Transl. Med.
18
185
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeutic drug target using a computational approach
2020
Aftab, S.O.; Ghouri, M.Z.; Masood, M.U.; Haider, Z.; Khan, Z.; Ahmad, A.; Munawar, N.
J. Transl. Med.
18
275
Non-nucleoside inhibitors of Zika Virus RNA-dependent RNA polymerase
2020
Gharbi-Ayachi, A.; Santhanakrishnan, S.; Wong, Y.H.; Chan, K.W.K.; Tan, S.T.; Bates, R.W.; Vasudevan, S.G.; El Sahili, A.; Lescar, J.
J. Virol.
94
e00794-20
Ribavirin, remdesivir, sofosbuvir, galidesivir, and tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp) A molecular docking study
2020
Elfiky, A.A.
Life Sci.
253
117592
The identity of a single residue of the RNA-dependent RNA polymerase of grapevine fanleaf virus modulates vein clearing in Nicotiana benthamiana
2019
Osterbaan, L.J.; Choi, J.; Kenney, J.; Flasco, M.; Vigne, E.; Schmitt-Keichinger, C.; Rebelo, A.R.; Heck, M.; Fuchs, M.
Mol. Plant Microbe Interact.
32
790-801
Quinolinecarboxamides inhibit the replication of the bovine viral diarrhea virus by targeting a hot spot for the inhibition of pestivirus replication in the RNA-dependent RNA polymerase
2020
Musiu, S.; Castillo, Y.P.; Muigg, A.; Puerstinger, G.; Leyssen, P.; Froeyen, M.; Neyts, J.; Paeshuyse, J.
Molecules
25
1283
Rapid incorporation of Favipiravir by the fast and permissive viral RNA polymerase complex results in SARS-CoV-2 lethal mutagenesis
2020
Shannon, A.; Selisko, B.; Le, N.T.; Huchting, J.; Touret, F.; Piorkowski, G.; Fattorini, V.; Ferron, F.; Decroly, E.; Meier, C.; Coutard, B.; Peersen, O.; Canard, B.
Nat. Commun.
11
4682
Structure of replicating SARS-CoV-2 polymerase
2020
Hillen, H.S.; Kokic, G.; Farnung, L.; Dienemann, C.; Tegunov, D.; Cramer, P.
Nature
584
154-156
The expression and activity of thymidine kinase 1 and deoxycytidine kinase are modulated by hydrogen peroxide and nucleoside analogs
2020
Sun, R.; Eriksson, S.; Wang, L.
Nucleosides Nucleotides Nucleic Acids
39
1347-1358
Identification of novel mutations in RNA-dependent RNA polymerases of SARS-CoV-2 and their implications on its protein structure
2020
Chand, G.B.; Banerjee, A.; Azad, G.K.
PeerJ
8
e9492
Nucleotide analogues as inhibitors of SARS-CoV polymerase
2020
Ju, J.; Li, X.; Kumar, S.; Jockusch, S.; Chien, M.; Tao, C.; Morozova, I.; Kalachikov, S.; Kirchdoerfer, R.N.; Russo, J.J.
Pharmacol. Res. Perspect.
8
e00674
The uncoupling of catalysis and translocation in the viral RNA-dependent RNA polymerase
2017
Shu, B.; Gong, P.
RNA Biol.
14
1314-1319
Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir
2020
Yin, W.; Mao, C.; Luan, X.; Shen, D.D.; Shen, Q.; Su, H.; Wang, X.; Zhou, F.; Zhao, W.; Gao, M.; Chang, S.; Xie, Y.C.; Tian, G.; Jiang, H.W.; Tao, S.C.; Shen, J.; Jiang, Y.; Jiang, H.; Xu, Y.; Zhang, S.; Zhang, Y.; Xu, H.E.
Science
368
1499-1504
Structure of the RNA-dependent RNA polymerase from COVID-19 virus
2020
Gao, Y.; Yan, L.; Huang, Y.; Liu, F.; Zhao, Y.; Cao, L.; Wang, T.; Sun, Q.; Ming, Z.; Zhang, L.; Ge, J.; Zheng, L.; Zhang, Y.; Wang, H.; Zhu, Y.; Zhu, C.; Hu, T.; Hua, T.; Zhang, B.; Yang, X.; Li, J.; Yang, H.; Liu, Z.; Xu, W.; Guddat, L.W.; Wang, Q.; Lou, Z.; Rao, Z.
Science
368
779-782
The RNA polymerase alpha subunit recognizes the DNA shape of the upstream promoter element
2020
Lara-Gonzalez, S.; Dantas Machado, A.C.; Rao, S.; Napoli, A.A.; Birktoft, J.; Di Felice, R.; Rohs, R.; Lawson, C.L.
Biochemistry
59
4523-4532
-
Human deoxycytidine kinase is a valuable biocatalyst for the synthesis of nucleotide analogues
2019
Hellendahl, K.; Kamel, S.; Wetterwald, A.; Neubauer, P.; Wagner, A.
Catalysts
9
997
Deoxycytidine kinase is downregulated under hypoxic conditions and confers resistance against cytarabine in acute myeloid leukaemia
2016
Degwert, N.; Latuske, E.; Vohwinkel, G.; Stamm, H.; Klokow, M.; Bokemeyer, C.; Fiedler, W.; Wellbrock, J.
Eur. J. Haematol.
97
239-244
The role of deoxycytidine kinase (dCK) in radiation-induced cell death
2016
Zhong, R.; Xin, R.; Chen, Z.; Liang, N.; Liu, Y.; Ma, S.; Liu, X.
Int. J. Mol. Sci.
17
1939
Deoxycytidine kinase participates in the regulation of radiation-induced autophagy and apoptosis in breast cancer cells
2018
Zhong, R.; Liang, B.; Xin, R.; Zhu, X.; Liu, Z.; Chen, Q.; Hou, Y.; Jin, Z.; Qi, M.; Ma, S.; Liu, X.
Int. J. Oncol.
52
1000-1010
Aminoglycoside heteroresistance in Acinetobacter baumannii AB5075
2018
Anderson, S.E.; Sherman, E.X.; Weiss, D.S.; Rather, P.N.
mSphere
3
e00271-18
Influence of major-groove chemical modifications of DNA on transcription by bacterial RNA polymerases
2016
Raindlova, V.; Janouskova, M.; Slavickova, M.; Perlikova, P.; Bohacova, S.; Milisavljevic, N.; Sanderova, H.; Benda, M.; Barvik, I.; Krasny, L.; Hocek, M.
Nucleic Acids Res.
44
3000-3012
Gre-family factors modulate DNA damage sensing by Deinococcus radiodurans RNA polymerase
2019
Agapov, A.; Esyunina, D.; Kulbachinskiy, A.
RNA Biol.
16
1711-1720