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Ligand (E/Z)-isobutyraldoxime

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.14.41

(E)-2-methylpropanal oxime + [reduced NADPH-hemoprotein reductase] + O2 = 2-hydroxy-2-methylpropanenitrile + [oxidized NADPH-hemoprotein reductase] + 2 H2O

741198

-

1.14.14.41

(E)-2-methylpropanal oxime = (Z)-2-methylpropanal oxime

741198

-

4.99.1.5

(E/Z)-isobutyraldoxime = isobutyrnitrile + H2O

677719

-

4.99.1.5

(E/Z)-isobutyraldoxime = isobutyronitrile + H2O

650189

-

1.14.14.41

2 entries

4.99.1.5

2 entries

Product in Enzyme-catalyzed Reactions (3 results)

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Show Product (3 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

1.14.14.38

L-valine + 2 O2 + 2 [reduced NADPH-hemoprotein reductase] = (E)-2-methylpropanal oxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O

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1.14.14.38

L-valine + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = (E)-2-methylpropanal oxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O

-

-

1.14.14.38

2 entries

1.14.14.39

L-valine + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = (E)-2-methylpropanal oxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O

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-

Enzyme Kinetic Parameters

k_cat Value (Turnover Number) (1 result)

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Show Turnover Number (1 entry)

EC NUMBER

TURNOVER NUMBER [1/S]

TURNOVER NUMBER MAXIMUM [1/S]

COMMENTARY

LITERATURE

1.14.14.41

0.35

-

pH 7.9, 28°C

741198

K_M Value (2 results)

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Show KM Value (2 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

4.99.1.5

0.538

-

-

677719

4.99.1.5

5.54

-

pH 7, 30°C

650189

4.99.1.5

2 entries

References & Links

Literature References (3)

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Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

650189

14556637

A gene cluster responsible for alkylaldoxime metabolism coexisting with nitrile hydratase and amidase in Rhodococcus globerulus A-4

2003

Xie, S.X.; Kato, Y.; Komeda, H.; Yoshida, S.; Asano, Y.

Biochemistry

42

12056-12066

677719

16003557

Molecular and enzymatic analysis of the "aldoxime-nitrile pathway" in the glutaronitrile degrader Pseudomonas sp. K-9

2006

Kato, Y.; Asano, Y.

Appl. Microbiol. Biotechnol.

70

92-101

741198

21045121

Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme

2011

Jorgensen, K.; Morant, A.V.; Morant, M.; Jensen, N.B.; Olsen, C.E.; Kannangara, R.; Motawia, M.S.; Moller, B.L.; Bak, S.

Plant Physiol.

155

282-292

Links to other databases for (E/Z)-isobutyraldoxime

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Show Links (1 entry)

ChEBI

PubChem

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