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Ligand (E/Z)-isobutyraldoxime Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C4 H9 NO
(E/Z)-isobutyraldoxime
SYJPAKDNFZLSMV-HWKANZROSA-N
(E)-2-methylpropanal oxime
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (4 results)
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(E)-2-methylpropanal oxime + [reduced NADPH-hemoprotein reductase] + O2 = 2-hydroxy-2-methylpropanenitrile + [oxidized NADPH-hemoprotein reductase] + 2 H2O
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(E)-2-methylpropanal oxime = (Z)-2-methylpropanal oxime
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(E/Z)-isobutyraldoxime = isobutyrnitrile + H2O
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(E/Z)-isobutyraldoxime = isobutyronitrile + H2O
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Product in Enzyme-catalyzed Reactions (3 results)
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L-valine + 2 O2 + 2 [reduced NADPH-hemoprotein reductase] = (E)-2-methylpropanal oxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
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L-valine + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = (E)-2-methylpropanal oxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
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L-valine + 2 [reduced NADPH-hemoprotein reductase] + 2 O2 = (E)-2-methylpropanal oxime + 2 [oxidized NADPH-hemoprotein reductase] + CO2 + 3 H2O
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Enzyme Kinetic Parameters
kcat Value (Turnover Number) (1 result)
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KM Value (2 results)
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References & Links Literature References (3)
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A gene cluster responsible for alkylaldoxime metabolism coexisting with nitrile hydratase and amidase in Rhodococcus globerulus A-4
2003
Xie, S.X.; Kato, Y.; Komeda, H.; Yoshida, S.; Asano, Y.
Biochemistry
42
12056-12066
Molecular and enzymatic analysis of the "aldoxime-nitrile pathway" in the glutaronitrile degrader Pseudomonas sp. K-9
2006
Kato, Y.; Asano, Y.
Appl. Microbiol. Biotechnol.
70
92-101
Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme
2011
Jorgensen, K.; Morant, A.V.; Morant, M.; Jensen, N.B.; Olsen, C.E.; Kannangara, R.; Motawia, M.S.; Moller, B.L.; Bak, S.
Plant Physiol.
155
282-292
Links to other databases for (E/Z)-isobutyraldoxime