Ligand cyclo-L-tryptophan-L-tryptophan

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Basic Ligand Information

Molecular Structure
Picture of cyclo-L-tryptophan-L-tryptophan (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C22H20N4O2
cyclo-L-tryptophan-L-tryptophan
DNHODRZUCGXYKU-PMACEKPBSA-N
Synonyms:
(3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione, cyclo(L-Trp-L-Trp), cyclo(L-tryptophanyl-L-tryptophanyl), cyclo-(L-Trp-L-Trp), cyclo-L-Trp-L-Trp

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dimethylallyl diphosphate + cyclo-L-Trp-L-Trp = diphosphate + 7-(3-methylbut-2-enyl)-cyclo-L-Trp-L-Trp
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-tryptophanyl-tRNATrp + L-tryptophanyl-tRNATrp = 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl)
show the reaction diagram
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2 L-tryptophanyl-tRNATrp = 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl)
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
cyclo(L-Trp-L-Trp) + O2 = ?
show the reaction diagram
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geranyl diphosphate + (3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione = (3S,6S)-3-([6-[(2E)-3,7-dimethylocta-2,6-dien-1-yl]-1H-indol-3-yl]methyl)-6-[(1H-indol-3-yl)methyl]piperazine-2,5-dione + (3S,6S)-3-([7-[(2Z)-3,7-dimethylocta-2,6-dien-1-yl]-1H-indol-3-yl]methyl)-6-[(1H-indol-3-yl)methyl]piperazine-2,5-dione + diphosphate
show the reaction diagram
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dimethylallyl diphosphate + cyclo-(L-Trp-L-Trp) = diphosphate + cyclo-(L-2-dimethylallyl-Trp-L-Trp)
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-tryptophanyl-tRNATrp + L-tryptophanyl-tRNATrp = 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl)
show the reaction diagram
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2 L-tryptophanyl-tRNATrp = 2 tRNATrp + cyclo(L-tryptophanyl-L-tryptophanyl)
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for cyclo-L-tryptophan-L-tryptophan

ChEBI
PubChem
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PubChem