Ligand 2-aminoadipate 6-semialdehyde

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Basic Ligand Information

Molecular Structure
Picture of 2-aminoadipate 6-semialdehyde (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H11NO3
2-aminoadipate 6-semialdehyde
GFXYTQPNNXGICT-UHFFFAOYSA-N
Synonyms:
2-aminoadipate-6-semialdehyde, 2-aminoadipate semialdehyde, 2-aminoadipic semialdehyde, alpha-aminoadipate delta-semialdehyde, alpha-aminoadipate semialdehyde, alpha-aminoadipic semialdehyde

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-aminoadipate semialdehyde + NAD+ + H2O = alpha-aminoadipate + NADH + H+
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-lysine + O2 + H2O = 2-aminoadipate 6-semialdehyde + H2O2 + NH3
show the reaction diagram
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N6-(L-1,3-dicarboxypropyl)-L-lysine + NADP+ + H2O = L-glutamate + 2-aminoadipate 6-semialdehyde + NADPH + H+
show the reaction diagram
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L-lysine + 2-oxoglutarate = 2-aminoadipate 6-semialdehyde + L-glutamate
show the reaction diagram
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L-lysine + pyruvate = 2-aminoadipate 6-semialdehyde + L-alanine
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
alpha-aminoadipic semialdehyde + NAD+ + H2O = alpha-aminoadipic acid + NADH + H+
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (23 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-lysine + pyruvate = 2-aminoadipate 6-semialdehyde + L-alanine
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (3 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
11.2
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production from holo-lys2

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.02
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-

References & Links

Links to other databases for 2-aminoadipate 6-semialdehyde

ChEBI
PubChem
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PubChem