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BRENDA support

Ligand (3S)-hydroxyhexadecanoyl-CoA

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Basic Ligand Information

Molecular Structure
Picture of (3S)-hydroxyhexadecanoyl-CoA (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C37H66N7O18P3S
(3S)-hydroxyhexadecanoyl-CoA
DEHLMTDDPWDRDR-BCIKBWLNSA-N
Synonyms:
(3S)-3-hydroxyhexadecanoyl-CoA, (S)-3-hydroxyhexadecanoyl-CoA, a long-chain (3S)-3-hydroxyacyl-CoA, a long-chain (S)-3-hydroxyacyl-CoA
Pathway Source
Pathways
KEGG
Fatty acid degradation, Fatty acid elongation, Fatty acid metabolism
MetaCyc
(8E,10E)-dodeca-8,10-dienol biosynthesis, Spodoptera littoralis pheromone biosynthesis

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a long-chain (S)-3-hydroxyacyl-CoA + NAD+ = a long-chain 3-oxoacyl-CoA + NADH + H+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
a long-chain (S)-3-hydroxyacyl-CoA + NAD+ = a long-chain 3-oxoacyl-CoA + NADH + H+
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (3 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
trans-2-hexadecenoyl-CoA + H2O = (3S)-3-hydroxyhexadecanoyl-CoA
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
competitive, 50% inhibition at 0.00075 mM, 90% inhibition by 0.004 mM
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Enzyme Kinetic Parameters

Ki Value (1 result)

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EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.00035
-
pH 8, 25°C

References & Links

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Links to other databases for (3S)-hydroxyhexadecanoyl-CoA

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ChEBI
PubChem
ChEBI
PubChem