Ligand dodecanoyl-[acyl-carrier protein]

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Basic Ligand Information

Molecular Structure
Picture of dodecanoyl-[acyl-carrier protein] (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C26H48N3O9PR2S
dodecanoyl-[acyl-carrier protein]
FBAMBKQBXSXHLC-UHFFFAOYSA-N
Synonyms:
C12-[acyl-carrier protein], dodecanoyl-ACP, dodecanoyl-acyl carrier protein, dodecanoyl-[Staphylococcus aureus acyl carrier protein], lauroyl-ACP, lauroyl-[acyl-carrier protein]


Show all pahtways known for Show all BRENDA pathways known for dodecanoyl-[acyl-carrier protein]

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
lauroyl-[acyl-carrier protein] + H2O = [acyl-carrier protein] + laurate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
malonyl-ACP + lauroyl-ACP = ?
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dodecanoyl-[acyl-carrier protein] + S-adenosyl-L-methionine = N-dodecanoyl-L-homoserine lactone + [acyl-carrier protein] + S-methyl-5'-thioadenosine
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dodecanoyl-[acyl-carrier protein] + (3-deoxy-alpha-D-manno-oct-2-ulopyranosylonate)-(2->4)-(3-deoxy-alpha-D-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-[[(3R)-3-hydroxytetradecanoyl]amino]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[[(3R)-3-hydroxytetradecanoyl]amino]-1-O-phosphono-alpha-D-glucopyranose = (3-deoxy-alpha-D-manno-oct-2-ulopyranosylonate)-(2->4)-(3-deoxy-alpha-D-manno-oct-2-ulopyranosylonate)-(2->6)-2-deoxy-2-[[(3R)-3-(dodecanoyloxy)tetradecanoyl]amino]-3-O-[(3R)-3-hydroxytetradecanoyl]-4-O-phosphono-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-[[(3R)-3-hydroxytetradecanoyl]amino]-1-O-phosphono-alpha-D-glucopyranose + an [acyl-carrier protein]
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
dodecenoyl-[Staphylococcus aureus acyl carrier protein] + NADPH + H+ = dodecanoyl-[Staphylococcus aureus acyl carrier protein] + NADP+
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2-dodecenoyl-acyl carrier protein + NADH = dodecanoyl-acyl carrier protein + NAD+
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Inhibitor in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
feedback inhibition; feedback inhibition
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competitive with respect to tetradecanoyl-[acyl-carrier protein], wild type enzyme and mutant enzyme M197R/R199H/T123K
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (9 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (16 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.007
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pH 7.5, 30°C

References & Links

Links to other databases for dodecanoyl-[acyl-carrier protein]

ChEBI
PubChem
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PubChem