Ligand H-Leu-Val-Tyr-4-methylcoumarinyl-7-amide

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Basic Ligand Information

Molecular Structure
Picture of H-Leu-Val-Tyr-4-methylcoumarinyl-7-amide (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C30H38N4O6
H-Leu-Val-Tyr-4-methylcoumarinyl-7-amide
LCXURRLYDBPUAM-DPZBCOQUSA-N
Synonyms:
Leu-Val-Tyr-4-methylcoumarinyl-7-amide, Leu-Val-Tyr-7-amido-4-methylcoumarin, Leu-Val-Tyr 4-methylcoumarin 7-amide

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Leu-Val-Tyr-4-methylcoumarinyl-7-amide + H2O = Leu-Val-Tyr + 7-amino-4-methylcoumarin
show the reaction diagram
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Leu-Val-Tyr 4-methylcoumarin 7-amide + H2O = ?
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
N-succinyl-LLVY-7-amido-4-methylcoumarin + H2O = N-succinyl-L-leucyl-L-leucine + Val-Tyr-7-amido-4-methylcoumarin + N-succinyl-L-leucine + Leu-Val-Tyr-7-amido-4-methylcoumarin
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.02
-
pH 7.0, 37°C, cathepsin L1
0.21
-
pH 7.0, 37°C, cathepsin L2

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0054
-
pH 7.0, 37°C, cathepsin L1
0.0038
-
pH 7.0, 37°C, cathepsin L2

References & Links

Links to other databases for H-Leu-Val-Tyr-4-methylcoumarinyl-7-amide

ChEBI
PubChem
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PubChem