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BRENDA support

Ligand L-cysteic acid

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Basic Ligand Information

Molecular Structure
Picture of L-cysteic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C3H7NO5S
L-cysteic acid
XVOYSCVBGLVSOL-REOHCLBHSA-N
Synonyms:
cysteate, cysteic acid, cysteine sulfonate, L-cysteate, L-cysteinic acid


Show all pahtways known for Show all BRENDA pathways known for L-cysteic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-cysteate = taurine + CO2
show the reaction diagram
-
L-cysteate + H2O = pyruvate + bisulfite + NH3
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-cysteic acid + H2O + O2 = ? + NH3 + H2O2
show the reaction diagram
-
L-cysteate = taurine + CO2
show the reaction diagram
-
L-Cysteic acid = ?
show the reaction diagram
-
L-cysteate + H2O = pyruvate + bisulfite + NH3
show the reaction diagram
-
L-Cysteate = D-Cysteate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
L-phosphoserine + sulfite = L-cysteate + phosphate
show the reaction diagram
-
L-Cys + sulfite = L-cysteate + H2S
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
5 mM, 2fold stimulation
-
1 mM, 151% of initial activity
-
stimulates
-

Inhibitor in Enzyme-catalyzed Reactions (18 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
weak inhibition
-
5.38 mM, 50% inhibition of brain KAT I, 1.55 mM, 50% inhibition of brain KAT II
-
0.1 mM, 40% inhibition
-
sulfo transition state mimic, competitive inhibitor
-
50 mM, 25% inhibition
-
-
-
-
-
poor
-

3D Structure of Enzyme-Ligand-Complex (PDB) (865 results)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

KM Value (8 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
5.4
-
-
11.7
-
pH 9.0, 30°C

Ki Value (7 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.4
-
pH 5.8, 37°C

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
12.6
-
pH 7.0, 37°C

References & Links

Links to other databases for L-cysteic acid

ChEBI
PubChem
ChEBI
PubChem