Ligand flurbiprofen

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Basic Ligand Information

Molecular Structure
Picture of flurbiprofen (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C15H13FO2
flurbiprofen
SYTBZMRGLBWNTM-UHFFFAOYSA-N

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
UDP-D-glucuronate + flurbiprofen = UDP + flurbiprofen beta-D-glucuronoside
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
flurbiprofen + H2O = ?
show the reaction diagram
-
ATP + flurbiprofen + CoA = AMP + diphosphate + flurbiprofenyl-CoA
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (34 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.062 mM, 50% inhibition
-

3D Structure of Enzyme-Ligand-Complex (PDB) (7 results)

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
TABLE ID
1.524
-
-
9113

IC50 Value (4 results)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
1.649
-
-
0.029
-
pH 7.4, 37C

References & Links

Links to other databases for flurbiprofen

ChEBI
PubChem
ChEBI
PubChem