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Properties of 3-methyladenine-DNA glycosylase from Escherichia coli
1978
Riazuddin, S.; Lindahl, T.
Biochemistry
17
2110-2118
Adaptation to alkylation resistance involves the induction of a DNA glycosylase
1982
Evensen, G.; Seeberg, E.
Nature
296
773-775
Induction of a DNA glycosylase for N-methylated purines is part of the adaptive response to alkylating agents
1982
Karran, P.; Hjelmgren, T.; Lindahl, T.
Nature
296
770-773
Two DNA glycosylases in Escherichia coli which release primarily 3-methyladenine
1982
Thomas, L.; Yang, C.H.; Goldthwait, D.A.
Biochemistry
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Cloning of Escherichia coli genes encoding 3-methyladenine DNA glycosylases I and II
1984
Clarke, N.D.; Kvaal, M.; Seeberg, E.
Mol. Gen. Genet.
197
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Nucleotide sequence of the tag gene from Escherichia coli
1986
Steinum, A.L.; Seeberg, E.
Nucleic Acids Res.
14
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Purification and characterization of 3-methyladenine DNA glycosylase I from Escherichia coli
1987
Bjelland, S.; Seeberg, E.
Nucleic Acids Res.
15
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DNA glycosylase enzymes induced during chemical adaptation of M. luteus
1987
Riazuddin, S.; Athar, A.; Ahmed, Z.; Lali, S.M.; Sohail, A.
Nucleic Acids Res.
15
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Expression of the E.coli 3-methyladenine DNA glycosylase I gene in mammalian cells reduces the toxic and mutagenic effects of methylating agents
1992
Klungland, A.; Fairbairn, L.; Watson, A.J.; Margison, G.P.; Seeberg, E.
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Expression of E. coli tag gene encoding 3-methyladenine glycosylase I in NIH-3T3 murine fibroblasts
1992
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Biochem. Biophys. Res. Commun.
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Physical and genetic mapping of the tag gene on the Escherichia coli chromosome
1993
Seeberg, E.
J. Bacteriol.
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Different efficiencies of the Tag and AlkA DNA glycosylases from Escherichia coli in the removal of 3-methyladenine from single-stranded DNA
1996
Bjelland, S.; Seeberg, E.
FEBS Lett.
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Effect of overexpression of E. coli 3-methyladenine-DNA glycosylase I (Tag) on survival and mutation induction in Salmonella typhimurium
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Tomicic, M.; Franekic, J.
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3-Methyladenine-DNA glycosylase I from Escherichia coli-computer modeling and supporting experimental evidence
2000
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Biochem. Biophys. Res. Commun.
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In vivo repair of methylation damage in Aag 3-methyladenine DNA glycosylase null mouse cells
2000
Smith, S.A.; Engelward, B.P.
Nucleic Acids Res.
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Influence of DNA structure on hypoxanthine and 1,N(6)-ethenoadenine removal by murine 3-methyladenine DNA glycosylase
2000
Wyatt, M.D.; Samson, L.D.
Carcinogenesis
21
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Fold-recognition analysis predicts that the Tag protein family shares a common domain with the helix-hairpin-helix DNA glycosylases
2002
Bujnicki, J.M.; Rychlewski, L.
DNA Repair
1
391-395
3-Methyladenine DNA glycosylase I is an unexpected helix-hairpin-helix superfamily member
2002
Drohat, A.C.; Kwon, K.; Krosky, D.J.; Stivers, J.T.
Nat. Struct. Biol.
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The S. cerevisiae Mag1 3-methyladenine DNA glycosylase modulates susceptibility to homologous recombination
2002
Hendricks, C.A.; Razlog, M.; Matsuguchi, T.; Goyal, A.; Brock, A.L.; Engelward, B.P.
DNA Repair
1
645-659
Solution structure and base perturbation studies reveal a novel mode of alkylated base recognition by 3-methyladenine DNA glycosylase I
2003
Cao, C.; Kwon, K.; Jiang, Y.L.; Drohat, A.C.; Stivers, J.T.
J. Biol. Chem.
278
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A novel zinc snap motif conveys structural stability to 3-methyladenine DNA glycosylase I
2003
Kwon, K.; Cao, C.; Stivers, J.T.
J. Biol. Chem.
278
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The Bacillus subtilis counterpart of the mammalian 3-methyladenine DNA glycosylase has hypoxanthine and 1,N6,ethenoadenine as preferred substrates
2004
Aamodt, R.M.; Falnes, P.; Johansen, R.F.; Seeberg, E.; Bjoras, M.
J. Biol. Chem.
279
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Interaction of estrogen receptor alpha with 3-methyladenine DNA glycosylase modulates transcription and DNA repair
2004
Likhite, V.S.; Cass, E.I.; Anderson, S.D.; Yates, J.R.; Nardulli, A.M.
J. Biol. Chem.
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Crystallization and preliminary X-ray diffraction studies of 3-methyladenine-DNA glycosylase II from Escherichia coli
1988
Yamagata, Y.; Odawara, K.; Tomita, K.; Nakabeppu, Y.; Sekiguchi, M.
J. Mol. Biol.
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DNA glycosylase activities for thymine residues oxidized in the methyl group are functions of the AlkA enzyme in Escherichia coli
1994
Bjelland, S.; Birkeland, N.K.; Benneche, T.; Volden, G.; Seeberg, E.
J. Biol. Chem.
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Specific binding of the DNA repair enzyme AlkA to a pyrrolidine-based inhibitor
1995
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J. Am. Chem. Soc.
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Release of sulfur mustard-modified DNA bases by Escherichia coli 3-methyladenine DNA glycosylase II
1996
Matijasevic, Z.; Stering, A.; Niu, T.Q.; Austin-Ritchie, P.; Ludlum, D.B.
Carcinogenesis
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Three-dimensional structure of a DNA repair enzyme, 3-methyladenine DNA glycosylase II, from Escherichia coli
1996
Yamagata, Y.; Kato, M.; Odawara, K.; Tokuno, Y.; Nakashima, Y.; Matsushima, N.; Yasumura, K.; Tomita, K.; Ihara, K.; Fujii, Y.; Nakabeppu, Y.; Sekiguchi, M.; Fujii, S.
Cell
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Endogenous and exogenous DNA lesions recognized by N-alkylpurine-DNA glycosylases
1998
Borys, E.; Kusmierek, J.T.
Acta Biochim. Pol.
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Altered expression of the DNA repair protein, N-methylpurine-DNA glycosylase (MPG) in breast cancer
1998
Cerda, S.R.; Turk, P.W.; Thor, A.D.; Weitzman, S.A.
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Hepsulfam induced DNA adducts and its excision repair by bacterial and mammalian 3-methyladenine DNA glycosylases
1998
Je, K.H.; Son, J.K.; O'Connor, T.R.; Lee, C.S.
Mol. Cells
8
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Tissue-specific expression and activation of N-methylpurine-DNA glycosylase in thymic carcinomas of transgenic mice expressing the SV40 large T-antigen gene
1998
Kim, N.K.; Lee, S.H.; Cha, K.Y.; Seo, J.S.
Mol. Cells
8
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Specific interaction of wild-type and truncated mouse N-methylpurine-DNA glycosylase with ethenoadenine-containing DNA
1998
Roy, R.; Biswas, T.; Hazra, T.K.; Roy, G.; Grabowski, D.T.; Izumi, T.; Srinivasan, G.; Mitra, S.
Biochemistry
37
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Enzymatic repair of 5-formyluracil. I. Excision of 5-formyluracil site-specifically incorporated into oligonucleotide substrates by alka protein (Escherichia coli 3-methyladenine DNA glycosylase II)
1999
Masaoka, A.; Terato, H.; Kobayashi, M.; Honsho, A.; Ohyama, Y.; Ide, H.
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Enzymatic repair of 5-formyluracil. II. Mismatch formation between 5-formyluracil and guanine during dna replication and its recognition by two proteins involved in base excision repair (AlkA) and mismatch repair (MutS)
1999
Terato, H.; Masaoka, A.; Kobayashi, M.; Fukushima, S.; Ohyama, Y.; Yoshida, M.; Ide, H.
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3-Methyladenine DNA glycosylases: structure, function, and biological importance
1999
Wyatt, M.D.; Allan, J.M.; Lau, A.Y.; Ellenberger, T.E.; Samson, L.D.
Bioessays
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DNA bending and a flip-out mechanism for base excision by the helix-hairpin-helix DNA glycosylase, Escherichia coli AlkA
2000
Hollis, T.; Ichikawa, Y.; Ellenberger, T.
EMBO J.
19
758-766
Mutation of a unique aspartate residue abolishes the catalytic activity but not substrate binding of the mouse N-methylpurine-DNA glycosylase (MPG)
2000
Roy, R.; Biswas, T.; Lee, J.C.; Mitra, S.
J. Biol. Chem.
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Methylpurine DNA glycosylase of the hyperthermophilic archaeon Archaeoglobus fulgidus
2002
Birkeland, N.K.; Anensen, H.; Knaevelsrud, I.; Kristoffersen, W.; Bjoras, M.; Robb, F.T.; Klungland, A.; Bjelland, S.
Biochemistry
41
12697-12705
Binding of specific DNA base-pair mismatches by N-methylpurine-DNA glycosylase and its implication in initial damage recognition
2002
Biswas, T.; Clos, L.J.2nd.; SantaLucia, J.Jr.; Mitra, S.; Roy, R.
J. Mol. Biol.
320
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1,N(2)-ethenoguanine, a mutagenic DNA adduct, is a primary substrate of Escherichia coli mismatch-specific uracil-DNA glycosylase and human alkylpurine-DNA-N-glycosylase
2002
Saparbaev, M.; Langouet, S.; Privezentzev, C.V.; Guengerich, F.P.; Cai, H.; Elder, R.H.; Laval, J.
J. Biol. Chem.
277
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3-Methyladenine-DNA glycosylase II: the crystal structure of an AlkA-hypoxanthine complex suggests the possibility of product inhibition
2002
Teale, M.; Symersky, J.; DeLucas, L.
Bioconjug. Chem.
13
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Novel repair activities of AlkA (3-methyladenine DNA glycosylase II) and endonuclease VIII for xanthine and oxanine, guanine lesions induced by nitric oxide and nitrous acid
2002
Terato, H.; Masaoka, A.; Asagoshi, K.; Honsho, A.; Ohyama, Y.; Suzuki, T.; Yamada, M.; Makino, K.; Yamamoto, K.; Ide, H.
Nucleic Acids Res.
30
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Imbalancing the DNA base excision repair pathway in the mitochondria; targeting and overexpressing N-methylpurine DNA glycosylase in mitochondria leads to enhanced cell killing
2003
Fishel, M.L.; Seo, Y.R.; Smith, M.L.; Kelley, M.R.
Cancer Res.
63
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Effects of substrate specificity on initiating the base excision repair of N-methylpurines by variant human 3-methyladenine DNA glycosylases
2005
Connor, E.E.; Wilson, J.J.; Wyatt, M.D.
Chem. Res. Toxicol.
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The Escherichia coli 3-methyladenine DNA glycosylase AlkA has a remarkably versatile active site
2004
O'Brien, P.J.; Ellenberger, T.
J. Biol. Chem.
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A new protein superfamily includes two novel 3-methyladenine DNA glycosylases from Bacillus cereus, AlkC and AlkD
2006
Alseth, I.; Rognes, T.; Lindback, T.; Solberg, I.; Robertsen, K.; Kristiansen, K.I.; Mainieri, D.; Lillehagen, L.; Kolsto, A.B.; Bjoras, M.
Mol. Microbiol.
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Biochemical characterization and DNA repair pathway interactions of Mag1-mediated base excision repair in Schizosaccharomyces pombe
2005
Alseth, I.; Osman, F.; Korvald, H.; Tsaneva, I.; Whitby, M.C.; Seeberg, E.; Bjoras, M.
Nucleic Acids Res.
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Structural basis for enzymatic excision of N1-methyladenine and N3-methylcytosine from DNA
2007
Leiros, I.; Nabong, M.P.; Gr?svik, K.; Ringvoll, J.; Haugland, G.T.; Uldal, L.; Reite, K.; Olsbu, I.K.; Knaevelsrud, I.; Moe, E.; Andersen, O.A.; Birkeland, N.K.; Ruoff, P.; Klungland, A.; Bjelland, S.
EMBO J.
26
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Substrate specificity and sequence-dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag)
2008
Lingaraju, G.M.; Kartalou, M.; Meira, L.B.; Samson, L.D.
DNA Repair
7
970-982
Involvement of 3-methyladenine DNA glycosylases Mag1p and Mag2p in base excision repair of methyl methanesulfonate-damaged DNA in the fission yeast Schizosaccharomyces pombe
2007
Kanamitsu, K.; Tanihigashi, H.; Tanita, Y.; Inatani, S.; Ikeda, S.
Genes Genet. Syst.
82
489-494
A new protein architecture for processing alkylation damaged DNA: the crystal structure of DNA glycosylase AlkD
2008
Rubinson, E.H.; Metz, A.H.; OQuin, J.; Eichman, B.F.
J. Mol. Biol.
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Expression, purification and characterization of codon-optimized human N-methylpurine-DNA glycosylase from Escherichia coli
2008
Adhikari, S.; Manthena, P.V.; Uren, A.; Roy, R.
Protein Expr. Purif.
58
257-262
Structure of Escherichia coli AlkA in complex with undamaged DNA
2010
Bowman, B.R.; Lee, S.; Wang, S.; Verdine, G.L.
J. Biol. Chem.
285
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Structure-function studies of an unusual 3-methyladenine DNA glycosylase II (AlkA) from Deinococcus radiodurans
2012
Moe, E.; Hall, D.R.; Leiros, I.; Monsen, V.T.; Timmins, J.; McSweeney, S.
Acta Crystallogr. Sect. D
68
703-712
A model for 3-methyladenine recognition by 3-methyladenine DNA glycosylase I (TAG) from Staphylococcus aureus
2012
Zhu, X.; Yan, X.; Carter, L.; Liu, H.; Graham, S.; Coote, P.; Naismith, J.
Acta Crystallogr. Sect. F
68
610-615
DNA-N-glycosylases process novel O-glycosidic sites in DNA
2013
Admiraal, S.; O'Brien, P.
Biochemistry
52
4066-4074
Physical and functional interactions between 3-methyladenine DNA glycosylase and topoisomerase I in mycobacteria
2012
Yang, Q.; Huang, F.; Hu, L.; He, Z.
Biochemistry
77
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Gas-phase studies of purine 3-methyladenine DNA glycosylase II (AlkA) substrates
2012
Michelson, A.Z.; Chen, M.; Wang, K.; Lee, J.K.
J. Am. Chem. Soc.
134
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Cheminformatic designing of de novo inhibitors to 3-methyl adenine DNA glycosylase I (LiTagA) from Leptospira interrogans serovar lai strain 56601
2013
Rajesh, S.; Sivaraman, T.
Med. Chem. Res.
22
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Interplay between base excision repair activity and toxicity of 3-methyladenine DNA glycosylases in an E. coli complementation system
2014
Troll, C.J.; Adhikary, S.; Cueff, M.; Mitra, I.; Eichman, B.F.; Camps, M.
Mutat. Res.
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Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM
2013
Finney-Manchester, S.P.; Maheshri, N.
Nucleic Acids Res.
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DNA alkylation lesions and their repair in human cells: Modification of the comet assay with 3-methyladenine DNA glycosylase (AlkD)
2012
Hasplova, K.; Hudecova, A.; Magdolenova, Z.; Bjoras, M.; Galova, E.; Miadokova, E.; Dusinska, M.
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Selective base excision repair of DNA damage by the non-base-flipping DNA glycosylase AlkC
2018
Shi, R.; Mullins, E.A.; Shen, X.X.; Lay, K.T.; Yuen, P.K.; David, S.S.; Rokas, A.; Eichman, B.F.
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