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Acyl-acyl carrier protein synthetase from Escherichia coli
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2004
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Novel diphenyl ethers: design, docking studies, synthesis and inhibition of enoyl ACP reductase of Escherichia coli and Escherichia coli
2006
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Molecular dynamics simulation studies of the wild-type, I21V, and I16T mutants of isoniazid-resistant Mycobacterium tuberculosis enoyl reductase (InhA) in complex with NADH: toward the understanding of NADH-InhA different affinities
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Insight through molecular mechanics Poisson-Boltzmann surface area calculations into the binding affinity of triclosan and three analogues for FabI, the E. coli enoyl reductase
2006
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Pyrrolidine carboxamides as a novel class of inhibitors of enoyl acyl carrier protein reductase from Mycobacterium tuberculosis
2006
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Crystallographic and pre-steady-state kinetics studies on binding of NADH to wild-type and isoniazid-resistant enoyl-ACP(CoA) reductase enzymes from Mycobacterium tuberculosis
2006
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Anti-protozoal and plasmodial FabI enzyme inhibiting metabolites of Scrophularia lepidota roots
2005
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Phytochemistry
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Inhibitors of FabI, an enzyme drug target in the bacterial fatty acid biosynthesis pathway
2008
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Crystallization and preliminary X-ray crystallographic analysis of enoyl-ACP reductase III (FabL) from Bacillus subtilis
2007
Kim, K.H.; Park, J.K.; Ha, B.H.; Moon, J.H.; Kim, E.E.
Acta Crystallogr. Sect. F
63
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Combined effect of epigallocatechin gallate and triclosan on enoyl-ACP reductase of Mycobacterium tuberculosis
2008
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Biochem. Biophys. Res. Commun.
368
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Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis
2007
Bonnac, L.; Gao, G.Y.; Chen, L.; Felczak, K.; Bennett, E.M.; Xu, H.; Kim, T.; Liu, N.; Oh, H.; Tonge, P.J.; Pankiewicz, K.W.
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Design and synthesis of 2-pyridones as novel inhibitors of the Bacillus anthracis enoyl-ACP reductase
2008
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Antistaphylococcal activities of CG400549, a new bacterial enoyl-acyl carrier protein reductase (FabI) inhibitor
2007
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2008
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Overexpression of sweet pepper glycerol-3-phosphate acyltransferase gene enhanced thermotolerance of photosynthetic apparatus in transgenic tobacco
2008
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2007
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Crystal structure of the Helicobacter pylori enoyl-acyl carrier protein reductase in complex with hydroxydiphenyl ether compounds, triclosan and diclosan
2007
Lee, H.H.; Moon, J.; Suh, S.W.
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69
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Dimeric and tetrameric forms of enoyl-acyl carrier protein reductase from Bacillus cereus
2010
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2009
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IUBMB Life
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A slow, tight binding inhibitor of InhA, the enoyl-acyl carrier protein reductase from Mycobacterium tuberculosis
2010
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LuxR-type quorum-sensing regulators that are detached from common scents
2010
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Detection of quorum sensing signal molecules and identification of an autoinducer synthase gene among biofilm forming clinical isolates of Acinetobacter spp.
2012
Anbazhagan, D.; Mansor, M.; Yan, G.O.; Md Yusof, M.Y.; Hassan, H.; Sekaran, S.D.
PLoS ONE
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Structures of trans-2-enoyl-CoA reductases from Clostridium acetobutylicum and Treponema denticola: insights into the substrate specificity and the catalytic mechanism
2013
Hu, K.; Zhao, M.; Zhang, T.; Zha, M.; Zhong, C.; Jiang, Y.; Ding, J.
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Thiolactomycin-based beta-ketoacyl-AcpM synthase A (KasA) inhibitors: fragment-based inhibitor discovery using transient one-dimensional nuclear overhauser effect NMR spectroscopy
2013
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Escherichia coli enoyl-acyl carrier protein reductase (FabI) supports efficient operation of a functional reversal of ?-oxidation cycle
2015
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Appl. Environ. Microbiol.
81
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Selectivity of pyridone- and diphenyl ether-based inhibitors for the Yersinia pestis FabV enoyl-ACP reductase
2016
Neckles, C.; Pschibul, A.; Lai, C.T.; Hirschbeck, M.; Kuper, J.; Davoodi, S.; Zou, J.; Liu, N.; Pan, P.; Shah, S.; Daryaee, F.; Bommineni, G.R.; Lai, C.; Simmerling, C.; Kisker, C.; Tonge, P.J.
Biochemistry
55
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Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI)
2015
Mehboob, S.; Song, J.; Hevener, K.E.; Su, P.C.; Boci, T.; Brubaker, L.; Truong, L.; Mistry, T.; Deng, J.; Cook, J.L.; Santarsiero, B.D.; Ghosh, A.K.; Johnson, M.E.
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25
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Crystal structures of Pseudomonas aeruginosa enoyl-ACP reductase (FabI) in the presence and absence of NAD+ and triclosan
2015
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Bull. Korean Chem. Soc.
36
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Analysis of enoyl-acyl carrier protein reductase structure and interactions yields an efficient virtual screening approach and suggests a potential allosteric site
2016
Ghattas, M.A.; Mansour, R.A.; Atatreh, N.; Bryce, R.A.
Chem. Biol. Drug Des.
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Biological evaluation of potent triclosan-derived inhibitors of the enoyl-acyl carrier protein reductase InhA in drug-sensitive and drug-resistant strains of Mycobacterium tuberculosis
2014
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Design, synthesis, and evaluation of new thiadiazole-based direct inhibitors of enoyl acyl carrier protein reductase (InhA) for the treatment of tuberculosis
2015
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Identification of a gene required for the formation of lyso-ornithine lipid, an intermediate in the biosynthesis of ornithine-containing lipids
2004
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Mol. Microbiol.
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The olsA gene mediates the synthesis of an ornithine lipid in Pseudomonas aeruginosa during growth under phosphate-limiting conditions, but is not involved in antimicrobial peptide susceptibility
2011
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Rhodobacter capsulatus OlsA is a bifunctional enyzme active in both ornithine lipid and phosphatidic acid biosynthesis
2007
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J. Bacteriol.
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Identification of a gene required for the biosynthesis of ornithine-derived lipids
2002
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Structural insight into conformational dynamics of non-active site mutations in KasA A Mycobacterium tuberculosis target protein
2019
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Gene
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High myristic acid content in the cyanobacterium Cyanothece sp. PCC 8801 results from substrate specificity of lysophosphatidic acid acyltransferase
2018
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Biochim. Biophys. Acta
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Substrate recognition and catalytic mechanism of the phosphate acyltransferase PlsX from Bacillus subtilis
2020
Jiang, Y.; Qin, M.; Guo, Z.
ChemBioChem
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beta-Ketoacyl-acyl carrier protein synthase I (KASI) plays crucial roles in the plant growth and fatty acids synthesis in tobacco
2016
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Int. J. Mol. Sci.
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Molecular cloning and characterization of two beta-ketoacyl-acyl carrier protein synthase I genes from Jatropha curcas L.
2017
Xiong, W.; Wei, Q.; Wu, P.; Zhang, S.; Li, J.; Chen, Y.; Li, M.; Jiang, H.; Wu, G.
J. Plant Physiol.
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Molecular basis for interactions between an acyl carrier protein and a ketosynthase
2019
Milligan, J.C.; Lee, D.J.; Jackson, D.R.; Schaub, A.J.; Beld, J.; Barajas, J.F.; Hale, J.J.; Luo, R.; Burkart, M.D.; Tsai, S.C.
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Cloning and function characterization of a beta-ketoacyl-acyl-ACP synthase I from coconut (Cocos nucifera L.) endosperm
2015
Yuan, Y.; Liang, Y.; Li, B.; Zheng, Y.; Luo, X.; Dongdong, L.
Plant Mol. Biol. Rep.
33
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Structural characterization of beta-ketoacyl ACP synthase I bound to platencin and fragment screening molecules at two substrate binding sites
2020
Patterson, E.I.; Nanson, J.D.; Abendroth, J.; Bryan, C.; Sankaran, B.; Myler, P.J.; Forwood, J.K.
Proteins
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