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Ligand tiliroside

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Inhibitor in Enzyme-catalyzed Reactions (4 results)

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Show Inhibitors (4 entries)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

1.1.1.21

-

739379

-

1.14.18.1

tyrosinase inhibitors from Marrubium velutinum and Marrubium cylleneum, flavone/flavonol acylated glucosides

685515

-

1.14.18.1

tyrosinase inhibitors from Marrubium velutinum, flavone/flavonol acylated glucosides

685515

-

1.14.18.1

2 entries

1.2.1.12

molecular docking studies. Tiliroside is stabilized by four hydrogen bonds with the amino acids Cys166, Ser134, and Ser110

696747

-

Enzyme Kinetic Parameters

IC₅₀ Value (1 result)

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Show IC50 Value (1 entry)

EC NUMBER

IC50 VALUE

IC50 VALUE MAXIMUM

COMMENTARY

LITERATURE

1.2.1.12

0.046

-

pH 7.5, 25°C

696747

References & Links

Literature References (3)

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Show Reference (3 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

685515

17287127

Identification of tyrosinase inhibitors from Marrubium velutinum and Marrubium cylleneum

2007

Karioti, A.; Protopappa, A.; Megoulas, N.; Skaltsa, H.

Bioorg. Med. Chem.

15

2708-2714

696747

19254846

Discovery of novel Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase inhibitors

2009

Freitas, R.F.; Prokopczyk, I.M.; Zottis, A.; Oliva, G.; Andricopulo, A.D.; Trevisan, M.T.; Vilegas, W.; Silva, M.G.; Montanari, C.A.

Bioorg. Med. Chem.

17

2476-2482

739379

27690380

Flavonoids from Litsea japonica inhibit AGEs formation and rat lense aldose reductase in vitro and vessel dilation in zebrafish

2016

Lee, I.S.; Kim, Y.J.; Jung, S.H.; Kim, J.H.; Kim, J.S.

Planta Med.

83

318-325

Links to other databases for tiliroside

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Show Links (1 entry)

ChEBI

PubChem