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Ligand arachidonoyl lysophosphatidylcholine Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C2 8 H5 0 NO7 P
arachidonoyl lysophosphatidylcholine
LAXQYRRMGGEGOH-SNPVRQPZSA-N
1-arachidonoyl-lysophosphatidylcholine, 1-arachidonoyl lysophosphatidylcholine, 1-arachidoyl-2-lysophosphatidylcholine, 20:4 lysophosphatidylcholine
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (2 results)
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arachidonoyl-CoA + 1-arachidoyl-2-lysophosphatidylcholine = CoA + 2-arachidonoyl-1-arachidoylphosphatidylcholine
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1-arachidoyl-2-lysophosphatidylcholine + H2O = 1-arachidoyl-sn-glycerol + phosphorylcholine
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Inhibitor in Enzyme-catalyzed Reactions (1 result)
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Enzyme Kinetic Parameters
KM Value (1 result)
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0.563
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Vmax 470 nmol/min mg
Ki Value (1 result)
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IC50 Value (1 result)
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References & Links Literature References (3)
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Biochemical and molecular characterization of a novel choline-specific glycerophosphodiester phosphodiesterase belonging to the nucleotide pyrophosphatase/phosphodiesterase family
2005
Sakagami, H.; Aoki, J.; Natori, Y.; Nishikawa, K.; Kakehi, Y.; Arai, H.
J. Biol. Chem.
280
23084-23093
Regulation of lipoxygenase activity by polyunsaturated lysophosphatidylcholines or their oxygenation derivatives
2008
Huang, L.S.; Kim, M.R.; Sok, D.E.
J. Agric. Food Chem.
56
7808-7814
Substrate preferences of a lysophosphatidylcholine acyltransferase highlight its role in phospholipid remodeling
2008
Kazachkov, M.; Chen, Q.; Wang, L.; Zou, J.
Lipids
43
895-902
Links to other databases for arachidonoyl lysophosphatidylcholine