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Ligand 1-hexanoyl-2-lysophosphatidylcholine

Basic Ligand Information

Molecular Structure

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Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (4 results)

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Show Substrate (4 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

3.1.1.5

1-hexanoyl-2-lysophosphatidylcholine + H2O = ?

705906

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3.1.1.5

1-hexanoyl-2-lysophosphatidylcholine + H2O = glycerophosphocholine + hexanoate

678465

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3.1.4.39

caproyl-lysophosphatidylcholine + H2O = 1-hexanoyl-sn-gycerol-3-phosphate + choline

680925

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3.1.4.39

hexanoyl-lysophosphatidylcholine + H2O = 1-hexanoyl-sn-gycerol-3-phosphate + choline

680925

-

3.1.1.5

2 entries

3.1.4.39

2 entries

Activator in Enzyme-catalyzed Reactions (1 result)

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Show Activating Compound (1 entry)

EC NUMBER

COMMENTARY

LITERATURE

ENZYME 3D STRUCTURE

3.4.21.6

i.e. C6lysoPC, binding constants in presence of Ca2+

650170

-

Enzyme Kinetic Parameters

K_M Value (2 results)

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Show KM Value (2 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

3.1.1.5

0.0992

-

Vmax: 121.3 micromol/h/mg protein

705906

3.1.1.5

0.0992

-

Vmax: 121.3 micromol/h/mg protein

705906

3.1.1.5

2 entries

References & Links

Literature References (4)

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Show Reference (4 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

650170

12056907

Specificity of soluble phospholipid binding sites on human factor Xa

2002

Banerjee, M.; Drummond, D.C.; Srivastava, A.; Daleke, D.; Lentz, B.R.

Biochemistry

41

7751-7762

678465

17604237

Enhanced preference for pi-bond containing substrates is correlated to Pro110 in the substrate-binding tunnel of Escherichia coli thioesterase I/protease I/lysophospholipase L1

2007

Lee, L.; Liaw, Y.; Lee, Y.; Shaw, J.

Biochim. Biophys. Acta

1774

959-967

680925

18175805

Murine and human autotaxin alpha, beta, gamma isoforms: Gene organization, tissue distribution and biochemical characterization

2008

Giganti, A.; Rodriguez, M.; Fould, B.; Moulharat, N.; Coge, F.; Chomarat, P.; Galizzi, J.P.; Valet, P.; Saulnier-Blache, J.S.; Boutin, J.A.; Ferry, G.

J. Biol. Chem.

283

7776-7789

705906

19588246

Purification and characterization of lysophospholipase C from pig brain

2010

Hung, N.D.; Kim, M.R.; Sok, D.E.

Neurochem. Res.

35

50-59

Links to other databases for 1-hexanoyl-2-lysophosphatidylcholine

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Show Links (1 entry)

ChEBI

PubChem

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