Ligand phenylacetone

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Basic Ligand Information

Molecular Structure
Picture of phenylacetone (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H10O
phenylacetone
QCCDLTOVEPVEJK-UHFFFAOYSA-N
Synonyms:
1-Phenyl-2-propanone, 1-phenylpropan-2-one, 1-phenylpropanone, 2-oxo-3-phenylpropane

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phenylacetone + NADPH + H+ + O2 = benzyl acetate + NADP+ + H2O
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-phenyl-2-propanol + NAD(P)+ = 1-phenylpropan-2-one + NAD(P)H + H+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (14 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phenylacetone + NADPH = phenylethanol + NADP+
show the reaction diagram
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phenylacetone + NADPH + H+ = (S)-1-phenyl-2-propanol + NADP+
show the reaction diagram
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1-phenylpropanone + NADPH + H+ = 1-phenylpropanol + NADP+
show the reaction diagram
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1-phenylpropanone + NADPH + H+ = 1-phenylpropanol + NADP+
show the reaction diagram
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phenylacetone + NADPH + H+ + O2 = benzylacetate + NADP+ + H2O
show the reaction diagram
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phenylacetone + NADPH + H+ + O2 = benzyl acetate + NADP+ + H2O
show the reaction diagram
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phenylacetone + NH3 + NADH + H+ = (R)-amphetamine + H2O + NAD+
show the reaction diagram
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cyanide + 1-phenylpropan-2-one = (2S)-2-hydroxy-2-methyl-3-phenylpropanenitrile
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-phenyl-2-propanol + NAD(P)+ = 1-phenylpropan-2-one + NAD(P)H + H+
show the reaction diagram
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cis-beta-methylstyrene + H2O2 = cis-beta-methylstyrene oxide + trans-beta-methylstyrene oxide + 1-phenyl-2-propanone + benzaldehyde + H2O
show the reaction diagram
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amphetamine + H2O + O2 = 1-phenylpropan-2-one + NH3 + H2O2
show the reaction diagram
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1-phenyl-2,4-butanedione + H2O = acetic acid + 1-phenyl-2-propanone
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (19 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1
-
pH 7.0, 25°C
0.7
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mutant enzyme K66Q/S149G/N262C, at pH 9.6 and 30°C

KM Value (19 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
4
-
mutant enzyme K66Q/S149G/N262C, at pH 9.6 and 30°C

References & Links

Links to other databases for phenylacetone

ChEBI
PubChem
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PubChem