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Dehydrations requiring vitamin B12 coenzyme
1971
Abeles, R.H.
The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )
5
481-497
Substrate specificity of coenzyme B12-dependent diol dehydrase: glycerol as both a good substrate and a potent inactivator
1976
Toraya, T.; Shirakashi, T.; Kosuga, T.; Fukui, S.
Biochem. Biophys. Res. Commun.
69
475-480
Kinetic investigations with inhibitors that mimic the posthomolysis intermediate in the reactions of coenzyme-B12-dependent glycerol dehydratase and diol deydratase
1997
Poppe, L.; Retey, J.
Eur. J. Biochem.
245
398-401
Glycerol fermentation in Klebsiella pneumoniae: functions of the coenzyme B12-dependent glycerol and diol dehydratases
1982
Forage, R.G.; Foster, M.A.
J. Bacteriol.
149
413-419
A cobamide-requiring glycerol dehydrase from an acrolein-forming Lactobacillus
1962
Smiley, K.L.; Sobolov, M.
Arch. Biochem. Biophys.
97
538-543
Purification and properties of glycerol dehydrase
1970
Schneider, Z.; Larsen, E.G.; Jacobson, G.; Johnson, B.C.; Pawelkiewicz, J.
J. Biol. Chem.
245
3388-3396
Studies on the thermal dissociation of glycerol dehydrase
1971
Schneider, Z.; Johnson, B.C.
Arch. Biochem. Biophys.
144
491-495
-
Determination of cobamide derivates in picomole quantities by means of glycerol dehydrase from Aerobacter aerogenes
1971
Pawelkiewicz, J.
Methods Enzymol.
18C
32-34
Allosteric interactions in glycerol dehydratase. Purification of enzyme and effects of positive and negative cooperativity for glycerol
1974
Stroinski, A.; Pawelkiewicz, J.; Johnson, B.C.
Arch. Biochem. Biophys.
162
321-330
Glycerol dehydratase from Aerobacter aerogenes
1975
Johnson, B.C.; Stroinski, A.; Schneider, Z.
Methods Enzymol.
42C
315-323
Study on the mechanism of action of adenosylcobalamin-dependent glycerol dehydratase from Aerobacter aerogenes. I. Role of structural components of adenosylcobalamin the formation of the active site of glycerol dehydratase
1977
Yakusheva, M.I.; Poznanskaya, A.A.; Pospelova, T.A.; Rudakova, I.P.; Yurkevich, A.M.; Yakovlev, V.A.
Biochim. Biophys. Acta
484
216-235
Immunochemical evidence for the difference between coenzyme-B12-dependent diol dehydratase and glycerol dehydratase
1977
Toraya, T.; Fukui, S.
Eur. J. Biochem.
76
285-289
Study of the mechanism of action of adenosylcobalamindependent glycerol dehydratase from Aerobacter aerogenes. II. The inactivation kinetics of glycerol dehydratase complexes with adenosylobalamin and its analogs
1977
Poznanskaya, A.A.; Yakusheva, M.I.; Yakolev, V.A.
Biochim. Biophys. Acta
484
236-243
Resolution of the coenzyme B-12-dependent dehydratases of Klebsiella sp. and Citrobacter freundii
1979
Forage, R.G.; Foster, M.A.
Biochim. Biophys. Acta
569
249-258
Distribution of coenzyme B12-dependent diol dehydratase and glycerol dehydratase in selected genera of Enterobacteriaceae and Propionibacteriaceae
1980
Toraya, T.; Kuno, S.; Fukui, S.
J. Bacteriol.
141
1439-1442
In situ reactivation of glycerol-inactivated coenzyme B12-dependent enzymes, glycerol dehydratase and diol dehydratase
1980
Honda, S.; Toraya, T.; Fukui, S.
J. Bacteriol.
143
1458-1465
Production of 3-hydroxypropionaldehyde from glycerol
1983
Slininger, P.J.; Bothast, R.J.; Smiley, K.L.
Appl. Environ. Microbiol.
46
62-67
Purification and characterization of glycerol dehydratase from Lactobacillus reuteri
1990
Talarico, T.L.; Dobrogosz, W.J.
Appl. Environ. Microbiol.
56
1195-1197
Cloning, sequencing, and high level expression of the genes encoding adenosylcobalamin-dependent glycerol dehydrase of Klebsiella pneumoniae
1996
Tobimatsu, T.; Azuma, M.; Matsubara, H.; Takatori, H.; Niida, T.; Nishimoto, K.; Satoh, H.; Hayashi, R.; Toraya, T.
J. Biol. Chem.
271
22352-22357
Cloning, sequencing, and overexpression of the genes encoding coenzyme B12-dependent glycerol dehydratase of Citrobacter freundii
1996
Seyfried, M; Daniel, R.; Gottschalk, G.
J. Bacteriol.
178
5793-5796
Properties and sequence of the coenzyme B12-dependent glycerol dehydratase of Clostridium pasteurianum
1998
Macis, L.; Daniel, R.; Gottschalk, G.
FEMS Microbiol. Lett.
164
21-28
Biochemistry of coenzyme B-12-dependent glycerol and diol dehydratases and organization of the encoding genes
1999
Daniel, R.; Bobik, T.A.; Gottschalk, G.
FEMS Microbiol. Rev.
22
553-566
Separation and characterization of the 1,3-propanediol and glycerol dehydrogenase activities from Clostridium butyricum E5 wild-type and mutant D
2001
Malaoui, H.; Marczak, R.
J. Appl. Microbiol.
90
1006-1014
Specificities of reactivating factors for adenosylcobalamin-dependent diol dehydratase and glycerol dehydratase
2000
Tobimatsu, T.; Kajiura, H.; Toraya, T.
Arch. Microbiol.
174
81-88
Insight into the mechanism of the B12-independent glycerol dehydratase from Clostridium butyricum: preliminary biochemical and structural characterization
2004
O'Brien, J.R.; Raynaud, C.; Croux, C.; Girbal, L.; Soucaille, P.; Lanzilotta, W.N.
Biochemistry
43
4635-4645
Radical catalysis of B12 enzymes: structure, mechanism, inactivation, and reactivation of diol and glycerol dehydratases
2000
Toraya, T.
Cell. Mol. Life Sci.
57
106-127
Identification and expression of the genes and purification and characterization of the gene products involved in reactivation of coenzyme B12-dependent glycerol dehydratase of Citrobacter freundii
2001
Seifert, C.; Bowien, S.; Gottschalk, G.; Daniel, R.
Eur. J. Biochem.
268
2369-2378
The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol
2002
Yamanishi, M.; Yunoki, M.; Tobimatsu, T.; Sato, H.; Matsui, J.; Dokiya, A.; Iuchi, Y.; Oe, K.; Suto, K.; Shibata, N.; Morimoto, Y.; Yasuoka, N.; Toraya, T.
Eur. J. Biochem.
269
4484-4494
Purification, characterization and subunits identification of the diol dehydratase of Lactobacillus collinoides
2002
Sauvageot, N.; Pichereau, V.; Louarme, L.; Hartke, A.; Auffray, Y.; Laplace, J.M.
Eur. J. Biochem.
269
5731-5737
-
(Hydroxyalkyl)cob(III)alamins as competitive inhibitors in coenzyme B12-dependent enzymic reactions. 1H-NMR structure analysis and kinetic studies with glycerol dehydratase and diol dehydratase
1999
Poppe, L.; Hull, W.E.; Nitsche, R.; Graf, T.; Stupperich, E.; Retey, J.
Helv. Chim. Acta
82
1250-1265
Identification and expression of the genes encoding a reactivating factor for adenosylcobalamin-dependent glycerol dehydratase
1999
Tobimatsu, T.; Kajiura, H.; Yunoki, M.; Azuma, M.; Toraya, T.
J. Bacteriol.
181
4110-4113
Characterization and mechanism of action of a reactivating factor for adenosylcobalamin-dependent glycerol dehydratase
2001
Kajiura, H.; Mori, K.; Tobimatsu, T.; Toraya, T.
J. Biol. Chem.
276
36514-36519
Crystal structure of substrate free form of glycerol dehydratase
2003
Liao, D.I.; Dotson, G.; Turner, I.Jr.; Reiss, L.; Emptage, M.
J. Inorg. Biochem.
93
84-91
Structure of glycerol dehydratase reactivase: a new type of molecular chaperone
2003
Liao, D.I.; Reiss, L.; Turner, I.; Dotson, G.
Structure
11
109-119
Cloning and sequence analysis of the dhaT gene of the 1,3-propanediol regulon from Klebsiella pneumoniae
2004
Zheng, Y.; Yang, C.; Baishan, F.
Biotechnol. Lett.
26
251-255
Enhancement of 1,3-propanediol production by Klebsiella pneumoniae with fumarate addition
2005
Lin, R.; Liu, H.; Hao, J.; Cheng, K.; Liu, D.
Biotechnol. Lett.
27
1755-1759
Microbial conversion of glycerol to 1,3-propanediol: physiological comparison of a natural producer, Clostridium butyricum VPI 3266, and an engineered strain, Clostridium acetobutylicum DG1(pSPD5)
2006
Gonzalez-Pajuelo, M.; Meynial-Salles, I.; Mendes, F.; Soucaille, P.; Vasconcelos, I.
Appl. Environ. Microbiol.
72
96-101
High-level expression of the 1,3-propanediol oxidoreductase from Klebsiella pneumoniae in Escherichia coli
2005
Fenghuan, W.; Huijin, Q.; He, H.; Tan, T.
Mol. Biotechnol.
31
211-219
Production of 1,3-propanediol from glycerol by recombinant E. coli using incompatible plasmids system
2007
Wang, F.; Qu, H.; Zhang, D.; Tian, P.; Tan, T.
Mol. Biotechnol.
37
112-119
Crystallization and preliminary X-ray characterization of 1,3-propanediol dehydrogenase from the human pathogen Klebsiella pneumoniae
2007
Marcal, D.; Rego, A.T.; Fogg, M.J.; Wilson, K.S.; Carrondo, M.A.; Enguita, F.J.
Acta Crystallogr. Sect. F
63
249-251
Development of a new bioprocess for production of 1,3-propanediol I.: modeling of glycerol bioconversion to 1,3-propanediol with Klebsiella pneumoniae enzymes
2008
Nemeth, A.; Sevella, B.
Appl. Biochem. Biotechnol.
144
47-58
Decrease of 3-hydroxypropionaldehyde accumulation in 1,3-propanediol production by over-expressing dhaT gene in Klebsiella pneumoniae TUAC01
2008
Hao, J.; Wang, W.; Tian, J.; Li, J.; Liu, D.
J. Ind. Microbiol. Biotechnol.
35
735-741
Cloning, expression, and characterization of an aldehyde dehydrogenase from Escherichia coli K-12 that utilizes 3-hydroxypropionaldehyde as a substrate
2008
Jo, J.E.; Mohan Raj, S.; Rathnasingh, C.; Selvakumar, E.; Jung, W.C.; Park, S.
Appl. Microbiol. Biotechnol.
81
51-60
Construction of a Novel Expression System in Klebsiella pneumoniae and its Application for 1,3-Propanediol Production
2010
Ma, Z.; Rao, Z.; Zhuge, B.; Fang, H.; Liao, X.; Zhuge, J.
Appl. Biochem. Biotechnol.
162
399-407
Microbial conversion of glycerol to 1,3-propanediol by an engineered strain of Escherichia coli
2009
Tang, X.; Tan, Y.; Zhu, H.; Zhao, K.; Shen, W.
Appl. Environ. Microbiol.
75
1628-1634
Elimination of by-product formation during production of propane-1,3-diol in Klebsiella pneumoniae by inactivation of glycerol oxidative pathway
2009
Seo, M.Y.; Seo, J.W.; Heo, S.Y.; Baek, J.O.; Rairakhwada, D.; Oh, B.R.; Seo, P.S.; Choi, M.H.; Kim, C.H.
Appl. Microbiol. Biotechnol.
84
527-534
Identification and utilization of a 1,3-propanediol oxidoreductase isoenzyme for production of 1,3-propanediol from glycerol in Klebsiella pneumoniae
2009
Seo, J.W.; Seo, M.Y.; Oh, B.R.; Heo, S.Y.; Baek, J.O.; Rairakhwada, D.; Luo, L.H.; Hong, W.K.; Kim, C.H.
Appl. Microbiol. Biotechnol.
85
659-666
Effects of over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase on bioconversion of glycerol into 1,3-propandediol by Klebsiella pneumoniae under micro-aerobic conditions
2009
Zhao, L.; Zheng, Y.; Ma, X.; Wei, D.
Bioprocess Biosyst. Eng.
32
313-320
-
Regulation of 3-hydroxypropionaldehyde accumulation in Klebsiella pneumoniae by overexpression of dhaT and dhaD genes
2009
Chen, Z.; Liu, H.; Liu, D.
Enzyme Microb. Technol.
45
305-309
-
Over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase in Klebsiella pneumoniae and their effects on conversion of glycerol into 1,3-propanediol in resting cell system
2009
Zhao, L.; Ma, X.; Zheng, Y.; Zhang, J.; Wei, G.; Wei, D.
J. Chem. Technol. Biotechnol.
84
626-632
3-Hydroxypropionaldehyde guided glycerol feeding strategy in aerobic 1,3-propanediol production by Klebsiella pneumoniae
2008
Hao, J.; Lin, R.; Zheng, Z.; Sun, Y.; Liu, D.
J. Ind. Microbiol. Biotechnol.
35
1615-1624
Development of recombinant Klebsiella pneumoniae DELTAdhaT strain for the co-production of 3-hydroxypropionic acid and 1,3-propanediol from glycerol
2011
Ashok, S.; Raj, S.M.; Rathnasingh, C.; Park, S.
Appl. Microbiol. Biotechnol.
90
1253-1265
-
A novel NAD+-dependent aldehyde dehydrogenase encoded by the puuC gene of Klebsiella pneumoniae DSM 2026 that utilizes 3-hydroxypropionaldehyde as a substrate
2010
Raj, S.; Rathnasingh, C.; Jung, W.; Selvakumar, E.; Park, S.
Biotechnol. Bioprocess Eng.
15
131-138
Relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design
2010
Ma, C.; Zhang, L.; Dai, J.; Xiu, Z.
J. Biotechnol.
146
173-178
-
Production of 3-hydroxypropionic acid from glycerol by a novel recombinant Escherichia coli BL21 strain
2008
Raj, S.M.; Rathnasingh, C.; Jo, J.-E.; Park, S.
Proc. Biochem.
32
1440-1446
Production of 3-hydroxypropionic acid from glycerol by recombinant Pseudomonas denitrificans
2013
Zhou, S.; Catherine, C.; Rathnasingh, C.; Somasundar, A.; Park, S.
Biotechnol. Bioeng.
110
3177-3187
Production of 3-hydroxypropionic acid from glycerol by recombinant Klebsiella pneumoniae DELTAdhaTDELTAyqhD which can produce vitamin B12 naturally
2013
Ashok, S.; Sankaranarayanan, M.; Ko, Y.; Jae, K.E.; Ainala, S.K.; Kumar, V.; Park, S.
Biotechnol. Bioeng.
110
511-524
Enhanced aldehyde dehydrogenase activity by regenerating NAD+ in Klebsiella pneumoniae and implications for the glycerol dissimilation pathways
2013
Li, Y.; Su, M.; Ge, X.; Tian, P.
Biotechnol. Lett.
35
1609-1615
Molecular cloning, co-expression, and characterization of glycerol dehydratase and 1,3-propanediol dehydrogenase from Citrobacter freundii
2013
Qi, X.; Deng, W.; Wang, F.; Guo, Q.; Chen, H.; Wang, L.; He, X.; Huang, R.
Mol. Biotechnol.
54
469-474
Expression and characterization of a novel 1,3-propanediol dehydrogenase from Lactobacillus brevis
2016
Qi, X.; Yun, J.; Qi, Y.; Zhang, H.; Wang, F.; Guo, Q.; Cao, Z.
Appl. Biochem. Biotechnol.
179
959-972
Identification and characterization of Klebsiella pneumoniae aldehyde dehydrogenases increasing production of 3-hydroxypropionic acid from glycerol
2013
Luo, L.H.; Seo, J.W.; Heo, S.Y.; Oh, B.R.; Kim, D.H.; Kim, C.H.
Bioprocess Biosyst. Eng.
36
1319-1326
Key enzymes catalyzing glycerol to 1,3-propanediol
2016
Jiang, W.; Wang, S.; Wang, Y.; Fang, B.
Biotechnol. Biofuels
9
57
-
Characterization of 1,3-propanediol oxidoreductase (DhaT) from Klebsiella pneumoniae J2B
2015
Lama, S.; Ro, S.; Seol, E.; Sekar, B.; Ainala, S.; Thangappan, J.; Song, H.; Seung, D.; Park, S.
Biotechnol. Bioprocess Eng.
20
971-979
NAD(+)-independent aldehyde oxidase catalyzes cofactor balanced 3-hydroxypropionic acid production in Klebsiella pneumoniae
2014
Li, Y.; Liu, L.; Tian, P.
Biotechnol. Lett.
36
2215-2221
Characterization and cofactor binding mechanism of a novel NAD(P)H-dependent aldehyde reductase from Klebsiella pneumoniae DSM2026
2013
Ma, C.W.; Zhang, L.; Dai, J.Y;, Xiu, Z.L.
J. Microbiol. Biotechnol.
23
1699-1707
-
Overexpression and characterization of the gene encoding 1,3-propanediol oxidoreductase of Citrobacter freundii
2014
Qi, X.; Zhu, J.; Luo, Y.; Lin, J.; Wang, X.; Ju, Z.; Chen, F.; Zhu, X.; Chen, H.; Sun, W.; Wang, L.
Key Eng. Mater.
636
121-124
Production of 1,3-propanediol from glycerol using the newly isolated Klebsiella pneumoniae J2B
2014
Durgapal, M.; Kumar, V.; Yang, T.H.; Lee, H.J.; Seung, D.; Park, S.
Bioresour. Technol.
159
223-231
Production of 1,3-propanediol from glycerol using the newly isolated Klebsiella pneumoniae J2B
2014
Durgapal, M.; Kumar, V.; Yang, T.H.; Lee, H.J.; Seung, D.; Park, S.
Bioresour. Technol.
159
223-231
Spectrophotometric assay for sensitive detection of glycerol dehydratase activity using aldehyde dehydrogenase
2017
Park, E.S.; Park, S.; Shin, J.S.
J. Biosci. Bioeng.
123
528-533
Production of 1,3-propanediol using a novel 1,3-propanediol dehydrogenase from isolated Clostridium butyricum and co-biotransformation of whole cells
2018
Yun, J.; Yang, M.; Magocha, T.A.; Zhang, H.; Xue, Y.; Zhang, G.; Qi, X.; Sun, W.
Biores. Technol.
247
838-843
Production of 1,3-propanediol using a novel 1,3-propanediol dehydrogenase from isolated Clostridium butyricum and co-biotransformation of whole cells
2018
Yun, J.; Yang, M.; Magocha, T.A.; Zhang, H.; Xue, Y.; Zhang, G.; Qi, X.; Sun, W.
Biores. Technol.
247
838-843
Xylan supplement improves 1,3-propanediol fermentation by Clostridium butyricum
2018
Apiwatanapiwat, W.; Vaithanomsat, P.; Thanapase, W.; Ratanakhanokchai, K.; Kosugi, A.
J. Biosci. Bioeng.
125
662-668
Xylan supplement improves 1,3-propanediol fermentation by Clostridium butyricum
2018
Apiwatanapiwat, W.; Vaithanomsat, P.; Thanapase, W.; Ratanakhanokchai, K.; Kosugi, A.
J. Biosci. Bioeng.
125
662-668
Improved production of 3-hydroxypropionic acid in engineered Escherichia coli by rebalancing heterologous and endogenous synthetic pathways
2020
Lee, T.; Min, W.; Kim, H.; Seo, J.
Biores. Technol.
299
122600
Improved production of 3-hydroxypropionic acid in engineered Escherichia coli by rebalancing heterologous and endogenous synthetic pathways
2020
Lee, T.; Min, W.; Kim, H.; Seo, J.
Biores. Technol.
299
122600
-
Intensifying niacin-based biosynthesis of NAD+ to enhance 3-hydroxypropionic acid production in Klebsiella pneumoniae
2021
Wu, S.; Zhao, P.; Li, Q.; Tian, P.
Biotechnol. Lett.
43
223-234
Physiological investigations of the influences of byproduct pathways on 3-hydroxypropionic acid production in Klebsiella pneumoniae
2019
Li, X.; Chen, L.; Wang, X.; Tian, P.
J. Basic Microbiol.
59
1195-1207
Physiological investigations of the influences of byproduct pathways on 3-hydroxypropionic acid production in Klebsiella pneumoniae
2019
Li, X.; Chen, L.; Wang, X.; Tian, P.
J. Basic Microbiol.
59
1195-1207
Engineering an aldehyde dehydrogenase toward its substrates, 3-hydroxypropanal and NAD+, for enhancing the production of 3-hydroxypropionic acid
2017
Park, Y.S.; Choi, U.J.; Nam, N.H.; Choi, S.J.; Nasir, A.; Lee, S.G.; Kim, K.J.; Jung, G.Y.; Choi, S.; Shim, J.Y.; Park, S.; Yoo, T.H.
Sci. Rep.
7
17155
Structural insights into the production of 3-hydroxypropionic acid by aldehyde dehydrogenase from Azospirillum brasilense
2017
Son, H.F.; Park, S.; Yoo, T.H.; Jung, G.Y.; Kim, K.J.
Sci. Rep.
7
46005
Structural insights into the production of 3-hydroxypropionic acid by aldehyde dehydrogenase from Azospirillum brasilense
2017
Son, H.F.; Park, S.; Yoo, T.H.; Jung, G.Y.; Kim, K.J.
Sci. Rep.
7
46005