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BRENDA support

Ligand 9-cis-retinol

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Basic Ligand Information

Molecular Structure
Picture of 9-cis-retinol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C20H30O
9-cis-retinol
FPIPGXGPPPQFEQ-MKOSUFFBSA-N
Pathway Source
Pathways

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
9-cis-retinol + NADP+ = 9-cis-retinal + NADPH + H+
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
9-cis-retinol + NAD+ = 9-cis-retinal + NADH
show the reaction diagram
-
9-cis-retinol + NAD+ = 9-cis-retinal + NADH + H+
show the reaction diagram
-
9-cis-retinol + NADP+ = 9-cis-retinal + NADPH
show the reaction diagram
-
9-cis-retinol + NADP+ = 9-cis-retinal + NADPH + H+
show the reaction diagram
-
myristoyl-CoA + 9-cis-retinol = 9-cis-retinyl myristate + CoA
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
9-cis-retinal + NADPH = 9-cis-retinol + NADP+
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
substrate inhibition above 0.001 mM
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.025
-
oxidation with NAD+

KM Value (10 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0022
-
pH 8, 37°C
0.019
-
-
0.0016
-
pH 7.4, 37°C
0.02376
-
at pH 7.0 and 37°C

References & Links

Links to other databases for 9-cis-retinol

ChEBI
PubChem
ChEBI
PubChem