Ligand 3-oxoalanine
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Basic Ligand Information
Molecular Structure

C3H5NO3
3-oxoalanine
XMTCKNXTTXDPJX-UHFFFAOYSA-N
2-aminomalonate-semialdehyde, 2-aminomalonate semialdehyde, 2-ammoniomalonate semialdehyde, Calpha-formylglycine
Roles as Enzyme Ligand
In Vivo Product in Enzyme-catalyzed Reactions (1 result)
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L-serine + NADP+ = 2-aminomalonate semialdehyde + NADPH
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Substrate in Enzyme-catalyzed Reactions (1 result)
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2-aminomalonate semialdehyde = 2-aminoacetaldehyde + CO2
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Product in Enzyme-catalyzed Reactions (3 results)
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D-serine + NADP+ = 2-aminomalonate semialdehyde + NADPH
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L-serine + NADP+ = 2-aminomalonate semialdehyde + NADPH
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L-serine + NAD(P)+ = 2-aminomalonate semialdehyde + NAD(P)H + H+
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Enzyme Kinetic Parameters
References & Links
Literature References (2)
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Cloning and sequencing of the serine dehydrogenase gene from Agrobacterium tumefaciens
2002
Fujisawa, H.; Nagata, S.; Chowdhury, E.K.; Matsumoto, M.; Misono, H.
Biosci. Biotechnol. Biochem.
66
1137-1139
Crystal structure of the NADP+ and tartrate-bound complex of L-serine 3-dehydrogenase from the hyperthermophilic archaeon Pyrobaculum calidifontis
2018
Yoneda, K.; Sakuraba, H.; Araki, T.; Ohshima, T.
Extremophiles
22
395-405
Links to other databases for 3-oxoalanine