Ligand isoquinoline

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Basic Ligand Information

Molecular Structure
Picture of isoquinoline (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C9H7N
isoquinoline
AWJUIBRHMBBTKR-UHFFFAOYSA-N
Synonyms:
Isoquinoline derivatives

Show all pahtways known for Show all pathways known for isoquinoline

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
Isoquinoline + acceptor + H2O = ?
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
isoquinoline + p-iodonitrotetrazolium violet = ?
show the reaction diagram
-
S-adenosyl-L-methionine + isoquinoline = S-adenosyl-L-homocysteine + ?
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
stimulates
-

Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50: 6.5 mM
-
slow inhibition in absence of an electron acceptor
-
5 mM, 47% inhibition in presence of Mg2+, 34% inhibition in absence of Mg2+
-
slight inhibition
-

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.016
-
with 2-(4-iodophenyl)-3-(4-nitrophenyl)-5-phenyl-tetrazolium chloride as cosubstrate
1.5
-
-

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
6.5
-
IC50: 6.5 mM

References & Links

Links to other databases for isoquinoline

ChEBI
PubChem
ChEBI
PubChem