Ligand Dodecanol

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Basic Ligand Information

Molecular Structure
Picture of Dodecanol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C12H26O
Dodecanol
WPYWMXNXEZFMAK-UHFFFAOYSA-N
Synonyms:
1-Dodecanol, dodecan-1-ol, lauryl alcohol, n-dodecanol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-dodecanol + O2 = dodecanal + H2O2
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
lauryl aldehyde + NADPH = lauryl alcohol + NADP+
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (36 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-dodecanol + 2 NAD+ + H2O = dodecanoic acid + 2 NADH + 2 H+
show the reaction diagram
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1-dodecanol + NAD+ = dodecanal + NADH
show the reaction diagram
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dodecan-1-ol + NADP+ = dodecanal + NADPH
show the reaction diagram
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1-dodecanol + acceptor = n-dodecanal + reduced acceptor
show the reaction diagram
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feruloyl-CoA + 1-dodecanol = CoA + (E)-dodecyl 3-(4-hydroxy-3-methoxyphenyl)acrylate
show the reaction diagram
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acetyl-CoA + dodecan-1-ol = CoA + dodecyl acetate
show the reaction diagram
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3'-phosphoadenylylsulfate + 1-dodecanol = adenosine 3',5'-bisphosphate + 1-dodecyl sulfate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (16 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-dodecanal + NADPH + H+ = dodecanol + NADP+
show the reaction diagram
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dodecanal + NAD(P)H = dodecan-1-ol + NAD(P)+
show the reaction diagram
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dodecanal + NADPH + H+ = dodecanol + NADP+
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dodecanal + NADH + H+ = dodecanol + NAD+
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lauroyl-CoA + 2 NADPH + 2 H+ = dodecanol + 2 NADP+ + coenzyme A
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dodecanyl palmitate + H2O = dodecanol + palmitate
show the reaction diagram
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n-dodecyl beta-D-glucopyranoside + H2O = 1-dodecanol + beta-D-glucose
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (4 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
in 100 mM MES buffer (pH 6.5) with 200 mM NADPH, 0.25 mM decanal, and 125 microg of FALDR fusion protein. 1 mM inhibits by 46%, 0.25 mM inhibits by 45%
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mixed-type inhibitor
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3D Structure of Enzyme-Ligand-Complex (PDB) (12 results)

Enzyme Kinetic Parameters

KM Value (12 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.33
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pH 5.5, 37C

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.000482
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in 50 mM phosphate buffer, pH 7.0 at 23C

References & Links

Links to other databases for Dodecanol

ChEBI
PubChem
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PubChem