Ligand 3-methyl-1-butanol

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of 3-methyl-1-butanol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H12O
3-methyl-1-butanol
LXPANUYRGQTONH-FTRWYGJKSA-N
Synonyms:
3-methyl-butanol, 3-methylbutan-1-ol, 3-Methylbutanol, iso-amyl alcohol, iso-amylalcohol, isoamyl alcohol, Isoamylalcohol, isopentan-1-ol, Isopentanol

Show all pahtways known for Show all BRENDA pathways known for 3-methyl-1-butanol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
isovaleraldehyde + NADPH + H+ = isoamyl alcohol + NADP+
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (31 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-methyl-1-butanol + NADP+ = ?
show the reaction diagram
-
isoamyl alcohol + NADP+ = ? + NADPH + H+
show the reaction diagram
-
3-methyl-butanol + NADPH + H+ = ?
show the reaction diagram
-
isoamyl alcohol + O2 = ? + H2O2
show the reaction diagram
-
3-methyl-1-butanol + ubiquinone = 3-methyl-1-butanal + ubiquinol
show the reaction diagram
-
iso-amyl alcohol + ferricyanide = 3-methylbutanol + ferrocyanide
show the reaction diagram
-
isopentanol + NAD+ + H2O = ? + NADH
show the reaction diagram
-
sucrose + 3-methyl-1-butanol = D-fructose + 3-methylbutyl alpha-D-glucoside
show the reaction diagram
-
isoamyl alcohol + acetic acid = isoamyl acetate
show the reaction diagram
-
isopentanol + phenyl alpha-D-galactoside = ?
show the reaction diagram
-
isoamyl alcohol + H2O = ?
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (22 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-methylbutyraldehyde + NADH + H+ = 3-methylbutanol + NAD+
show the reaction diagram
-
-
isovaleraldehyde + NADPH + H+ = isoamyl alcohol + NADP+
show the reaction diagram
-
-
3-methylbutanal + NADPH = 3-methylbutanol + NADP+
show the reaction diagram
-
-
iso-amyl alcohol + ferricyanide = 3-methylbutanol + ferrocyanide
show the reaction diagram
-
-
isopentane + NADH + H+ + O2 = 3-methyl-1-butanol + 2-methyl-1-butanol + NAD+ + H2O
show the reaction diagram
-
-
isopentane + NAD(P)H + O2 = 2-methylbutan-1-ol + 3-methylbutan-1-ol + 2-methylbutan-2-ol + 3-methylbutan-2-ol + NADP+ + H2O
show the reaction diagram
-
isopentyl octanoate + H2O = isopentanol + octanoate
show the reaction diagram
-
3-methylbutyl acetate + H2O = 3-methylbutanol + acetate
show the reaction diagram
-
-
isoamyl gallate + H2O = gallic acid + isoamyl alcohol
show the reaction diagram
-
-
isoamyl acetate + H2O = isoamyl alcohol + acetate
show the reaction diagram
-
-

Activator in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
activates
-
activates 1.5fold at 30% v/v
-

Inhibitor in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
about 80% inhibition at 1% (v/v)
-
about 80% residual activity at 1 mM
-
inhibits 31% at 2% v/v and 38% at 5% v/v
-
70% inhibition at 10%, 90% at 20%
-
10% v/v, about 35% loss of activity
-
inhibits 80% and 97% at 5% and 10% v/v, respectively
-
Ki: 0.98 mM
-
2% (v/v), 29.9% inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (5 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.417
-
pH 7.5, 37°C

KM Value (12 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
197
-
at pH 7.0 and 25°C
0.27
-
-
4.2
-
-
5.6
-
wild-type, temperature not specified in the publication, pH not specified in the publication

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.98
-
-

References & Links

Links to other databases for 3-methyl-1-butanol

ChEBI
PubChem
-
PubChem