print visible entries

print all entries

Ligand 2-Chloroadenosine 5'-triphosphate

Basic Ligand Information

Molecular Structure

close all tables

open all tables

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

top print hide

Show Substrate (6 entries)

EC NUMBER

REACTION

REACTION DIAGRAM

LITERATURE

ENZYME 3D STRUCTURE

6.1.1.11

2-chloroadenosine 5'-triphosphate + L-serine + tRNASer = 2-chloroadenosine 5'-monophosphate + diphosphate + L-seryl-tRNASer

87

-

6.1.1.19

2-chloroadenosine 5'-triphosphate + L-arginine + tRNAArg = 2-chloroadenosine 5'-monophosphate + diphosphate + L-arginyl-tRNAArg

280

-

6.1.1.20

2-chloroadenosine 5'-triphosphate + phenylalanine + tRNAPhe = 2-chloroadenosine 5'-monophosphate + diphosphate + phenylalanyl-tRNAPhe

340, 347

-

6.1.1.3

2-Chloroadenosine 5'-triphosphate + L-threonine + tRNAThr = ?

273, 411

-

6.1.1.6

2-chloroadenosine 5'-triphosphate + lysine + tRNALys = 2-chloroadenosine 5'-monophosphate + Lys-tRNALys + diphosphate

273

-

6.1.1.9

2-chloroadenosine 5'-triphosphate + L-valine + tRNAVal = 2-chloroadenosine 5'-monophosphate + diphosphate + L-valyl-tRNAVal

469

-

Enzyme Kinetic Parameters

K_M Value (14 results)

top print hide

Show KM Value (14 entries)

EC NUMBER

KM VALUE [MM]

KM VALUE MAXIMUM [MM]

COMMENTARY

LITERATURE

6.1.1.11

0.05

-

-

87

6.1.1.19

1.3

-

NTP-diphosphate exchange

280

6.1.1.19

2.5

-

aminoacylation

280

6.1.1.20

0.05

-

aminoacylation

347

6.1.1.20

0.096

-

mitochondrial

340

6.1.1.20

0.11

-

-

340

6.1.1.20

0.16

-

cytoplasmic

340

6.1.1.20

0.16

-

mitochondrial

340

6.1.1.20

0.2

-

-

340

6.1.1.20

0.2

-

cytoplasmic, 2'-deoxyadenosine 5'-triphosphate

340

6.1.1.20

0.2

-

mitochondrial, 3'-deoxyadenosine 5'-triphosphate

340

6.1.1.3

0.4

-

-

273

6.1.1.3

0.4

-

ATP

411

6.1.1.19

2 entries

6.1.1.20

8 entries

6.1.1.3

2 entries

6.1.1.6

0.1

-

aminoacylation

273

References & Links

Literature References (7)

top print hide

Show Reference (7 entries)

BRENDA REFERENCE ID

PUBMED ID

TITLE

YEAR

AUTHORS

JOURNAL

VOLUME

PAGES

87

776617

Phenylalanyl-tRNA and seryl-tRNA synthetases from baker's yeast. Substrate specificity with regard to ATP analogs and mechanism of the aminoacylation reaction

1976

Freist, W.; von der Haar, F.; Sprinzl, M.; Cramer, F.

Eur. J. Biochem.

64

389-393

273

346350

Threonyl-tRNA, lysyl-tRNA and arginyl-tRNA synthetases from baker's yeast. Substrate specificity with regard to ATP analogues

1978

Freist, W.; Sternbach, H.; von der Haar, F.; Cramer, F.

Eur. J. Biochem.

84

499-502

280

7042510

Arginyl-tRNA synthetase from Escherichia coli K12: specificity with regard to ATP analogs and their magnesium complexes

1982

Gerlo, E.; Freist, W.; Charlier, J.

Hoppe-Seyler's Z. Physiol. Chem.

363

365-373

340

6754571

Phenylalanyl-tRNA synthetases from hen liver cytoplasm and mitochondria, yeast cytoplasm and mitochondria, and from Escherichia coli: substrate specificity relationship with regard to ATP analogs

1982

Gabius, H.J.; Freist, W.; Cramer, F.

Hoppe-Seyler's Z. Physiol. Chem.

363

1241-1246

347

6373755

Phenylalanyl-tRNA synthetase from the archaebacterium Methanosarcina barkeri

1984

Rauhut, R.; Gabius, H.J.; Kuhn, W.; Cramer, F.

J. Biol. Chem.

259

6340-6345

411

7459319

Purification and structural characterization of rat liver threonyl transfer ribonucleic acid synthetase

1980

Dignam, J.D.; Rhodes, D.G.; Deutscher, M.P.

Biochemistry

19

4978-4984

469

782885

Valyl-tRNA, isoleucyl-tRNA and tyrosyl-tRNA synthetase from baker's yeast. Substrate specificity with regard to ATP analogs and mechanism of the aminoacylation reaction

1976

Freist, W.; von der Haar, F.; Faulhammer, H.; Cramer, F.

Eur. J. Biochem.

66

493-497

Links to other databases for 2-Chloroadenosine 5'-triphosphate

top print hide

Show Links (1 entry)