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BRENDA support

Ligand phenylphosphorodiamidate

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Basic Ligand Information

Molecular Structure
Picture of phenylphosphorodiamidate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
Molfile
C6H9N2O2P
phenylphosphorodiamidate
AYRRNFHDJUXLEQ-UHFFFAOYSA-N
Synonyms:
phenyl phosphorodiamate, phenyl phosphorodiamidate, phenylphosphorodiamide

Roles as Enzyme Ligand

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
Glu395 is directly interacting with amino group of the inhibitor
-
competitive inhibitor, the inhibitory effect is fully reversed by SSAM substrate benzamide, demonstrating the hydrophobicity of the active site
-

Enzyme Kinetic Parameters

Ki Value (1 result)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3.2
-
pH 9.5, recombinant enzyme

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
0.000003
-
-

References & Links

Links to other databases for phenylphosphorodiamidate

EXTERNAL LINKS