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Ligand L-alanine methyl ester Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
Basic Ligand Information Molecular Structure
C4 H9 NO2
L-alanine methyl ester
DWKPPFQULDPWHX-VKHMYHEASA-N
L-Ala-OMe, L-alanyl methyl ester, methyl L-alaninate
Roles as Enzyme Ligand
Substrate in Enzyme-catalyzed Reactions (4 results)
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pimeloyl-CoA + L-alanine methyl ester = ?
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L-alanyl methyl ester + L-tryptophan = L-alanyl-L-tryptophan + methanol
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L-Ala-OMe + L-Pro-OBzl = L-Pro-L-Ala-OMe + benzyl alcohol
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ATP + UDP-N-acetylmuramate + methyl L-alaninate = ADP + phosphate + methyl UDP-N-acetylmuramoyl-L-alaninate
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Product in Enzyme-catalyzed Reactions (2 results)
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L-cysteine methyl ester = L-alanine methyl ester + H2S
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N-glutaryl-L-alanine methyl ester + H2O = glutarate + L-alanine methyl ester
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Enzyme Kinetic Parameters
KM Value (1 result)
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References & Links Literature References (4)
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Kinetic and crystallographic studies of Escherichia coli UDP-N-acetylmuramate:L-alanine ligase
1996
Emanuele, J.J.; Jin, H.; Jacobson, B.L.; Chang, C.Y.; Einspahr, H.M.; Villafranca, J.J.
Protein Sci.
5
2566-2574
Mechanism of alpha-oxoamine synthases: identification of the intermediate Claisen product in the 8-amino-7-oxononanoate synthase reaction
2006
Kerbarh, O.; Campopiano, D.J.; Baxter, R.L.
Chem. Commun. (Camb. )
2006
60-62
The aminolysis reaction of streptomyces S9 aminopeptidase promotes the synthesis of diverse prolyl dipeptides
2010
Arima, J.; Morimoto, M.; Usuki, H.; Mori, N.; Hatanaka, T.
Appl. Environ. Microbiol.
76
4109-4112
Purification and characterization of Stenotrophomonas maltophilia-derived l-amino acid ester hydrolase for synthesizing dipeptide, isoleucyl-tryptophan
2018
Hossain, M.S.; Tanaka, T.; Takagi, K.; Hayashi, J.; Wakayama, M.
3 Biotech
8
173
Links to other databases for L-alanine methyl ester