Ligand phytosphingosine

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Basic Ligand Information

Molecular Structure
Picture of phytosphingosine (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C18H39NO3
phytosphingosine
AERBNCYCJBRYDG-KSZLIROESA-N
Synonyms:
4-hydroxysphinganine, C18-phytosphinganine, C18-phytosphingosine, D-erythro-phytosphingosine

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
an ultra-long-chain fatty acyl-CoA + phytosphingosine = phytoceramide + CoA
show the reaction diagram
-
ATP + phytosphingosine = ADP + phytosphingosine 1-phosphate
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
phytoceramide + H2O = phytosphingosine + fatty acid
show the reaction diagram
-
-

Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-hydroxysphinganine + reduced acceptor + H2O = 4-hydroxy-trans-8-sphingenine + acceptor + H2O
show the reaction diagram
-
an ultra-long-chain fatty acyl-CoA + phytosphingosine = phytoceramide + CoA
show the reaction diagram
-
ATP + phytosphingosine = ADP + phytosphingosine 1-phosphate
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (11 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Inhibitor in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
non-competitive inhibition
-
0.0025 mM, 21% inhibition; 0.0025 mM, 64% inhibition
-

Enzyme Kinetic Parameters

KM Value (2 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for phytosphingosine

ChEBI
PubChem
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PubChem