Ligand polysialic acid

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Basic Ligand Information

Molecular Structure
Picture of polysialic acid (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C55H85N5O41R2
polysialic acid
RUSZQPVTHFFKON-MZBJOSPHSA-N
Synonyms:
poly(sialic) acid, Poly(sialic) acids or oligo(sialic) acids containing alpha-2,8-linked N-acetylneuraminic acid

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
poly(sialic) acids or oligo(sialic) acids containing alpha-2,8-linked N-acetylneuraminic acid + H2O = fragments of poly(sialic) acid or oligo(sialic) acids
show the reaction diagram
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polysialic acid + H2O = sialic acid
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
0.0001 mg/ml increases BACE1 activity by 160%
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (6 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for polysialic acid

ChEBI
PubChem
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PubChem