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BRENDA support

Ligand tetradecanal

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Basic Ligand Information

Molecular Structure
Picture of tetradecanal (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C14H28O
tetradecanal
UHUFTBALEZWWIH-UHFFFAOYSA-N
Synonyms:
1-Tetradecanal, myristaldehyde, myristic aldehyde, n-tetradecanal, tetradecyl aldehyde

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tetradecanal + FMNH2 + O2 = tetradecanoate + FMN + H2O + hn
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tetradecanoyl-CoA + NADPH + H+ = tetradecanal + CoA + NADP+
show the reaction diagram
-
tetradecanoyl-CoA + NADPH + H+ = tetradecanal + CoA + NADP+
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tetradecanal + NAD(P)H = tetradecan-1-ol + NAD(P)+
show the reaction diagram
-
tetradecanal + NADP+ = tetradecanoate + NADPH
show the reaction diagram
-
n-tetradecanal + NADP+ + H2O = n-tetradecanoate + NADPH + H+
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (12 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
tetradecan-1-ol + NAD+ = tetradecanal + NADH + H+
show the reaction diagram
-
tetradecan-1-ol + NADP+ = tetradecanal + NADPH + H+
show the reaction diagram
-
1-tetradecanol + NADP+ = tetradecanal + NADPH + H+
show the reaction diagram
-
1-tetradecanol + O2 = tetradecanal + H2O2
show the reaction diagram
-
1-tetradecanol + acceptor = n-tetradecanal + reduced acceptor
show the reaction diagram
-
2-trans-tetradecenal + NADPH = tetradecanal + NADP+
show the reaction diagram
-

Inhibitor in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
IC50 in the range 1-100 mM
-
competitively inhibits the ceramide synthesis activity, 2.5-3 mol%, about 50% inhibition
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
0.86
-
-

KM Value (4 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.014
-
-
0.015
-
-

IC50 Value (1 result)

EC NUMBER
IC50 VALUE
IC50 VALUE MAXIMUM
COMMENTARY
LITERATURE
1
100
IC50 in the range 1-100 mM

References & Links

Links to other databases for tetradecanal

ChEBI
PubChem
ChEBI
PubChem