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Ligand Kdo2-lipid A
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Basic Ligand Information
(KDO)2-lipid A, 3-deoxy-alpha-D-manno-oct-2-ulopyranonosyl-(2->4)-3-deoxy-alpha-D-manno-oct-2-ulopyranonosyl-(2->6)-2-deoxy-2-{[(3R)-3-(dodecanoyloxy)tetradecanoyl]amino}-4-O-phosphono-3-O-[(3R)-3-(tetradecanoyloxy)tetradecanoyl]-beta-D-glucopyranosyl-(1->6)-2-deoxy-3-O-[(3R)-3-hydroxytetradecanoyl]-2-{[(3R)-3-hydroxytetradecanoyl]amino}-1-O-phosphono-alpha-D-glucopyranose, 3-deoxyoctulosonyl-lipopolysaccharide, alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A, di[3-deoxy-D-manno-octulosonyl]-lipid A, Re endotoxin
BRENDA
Show all BRENDA pathways known for Kdo2-lipid A
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open all tablesRoles as Enzyme Ligand
In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)
top
EC NUMBER 
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-lipid A + ditrans,octacis-undecaprenyl phosphate
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4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A = alpha-Kdo-(2->4)-Kdo-(2->6)-[4-P-L-Ara4N]-lipid A + ditrans,octacis-undecaprenyl phosphate
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Substrate in Enzyme-catalyzed Reactions (5 results)
EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(2Z)-3,7-dimethylocta-2,6-dien-1-yl 1-O-(4-amino-4-deoxy-alpha-L-arabinopyranosyl) phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A = ?
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4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A = alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-[4-P-L-Ara4N]-lipid A + ditrans,octacis-undecaprenyl phosphate
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4-amino-4-deoxy-alpha-L-arabinopyranosyl ditrans,octacis-undecaprenyl phosphate + alpha-Kdo-(2->4)-alpha-Kdo-(2->6)-lipid A = alpha-Kdo-(2->4)-Kdo-(2->6)-[4-P-L-Ara4N]-lipid A + ditrans,octacis-undecaprenyl phosphate
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Activator in Enzyme-catalyzed Reactions (2 results)
Inhibitor in Enzyme-catalyzed Reactions (2 results)
3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)
Enzyme Kinetic Parameters
References & Links
Literature References (11)
Links to other databases for Kdo2-lipid A
ChEBI
PubChem
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Release 2023.1 (January 2023)
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