Ligand isophthalate

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

Basic Ligand Information

Molecular Structure
Picture of isophthalate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H6O4
isophthalate
WPVINHLVHHPBMK-ULQDDVLXSA-N
Synonyms:
3-carboxybenzoate, Benzene-1,3-dicarboxylate, Benzene 1,3-dicarboxylate, isophthalic acid, m-carboxybenzoate

Roles as Enzyme Ligand

Substrate in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
ATP + isophthalate + CoA = AMP + diphosphate + isophthalyl-CoA
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3-carboxybenzaldehyde + NAD+ + H2O = 3-carboxybenzoate + NADH + 2 H+
show the reaction diagram
-
-
3-carboxybenzaldehyde + NADP+ + H2O = 3-carboxybenzoate + NADPH + 2 H+
show the reaction diagram
-
-
isophthalaldehyde + O2 + H2O = isophthalic acid + H2O2
show the reaction diagram
-
-
isophthalonitrile + H2O = isophthalate + NH3
show the reaction diagram
-
-

Inhibitor in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
10 mM, 42% inhibition
-

Enzyme Kinetic Parameters

Ki Value (8 results)

EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.5
-
competitive inhibition with respect to 2-oxoglutarate and noncompetitive with respect to Fe2+ and the peptide substrate
0.5
-
-
0.28
-
-
6.9
-
-

References & Links

Links to other databases for isophthalate

ChEBI
PubChem
-
PubChem