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BRENDA support

Ligand 4-guanidinobutanoate

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Basic Ligand Information

Molecular Structure
Picture of 4-guanidinobutanoate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H11N3O2
4-guanidinobutanoate
TUHVEAJXIMEOSA-UHFFFAOYSA-M
Synonyms:
4-guanidinebutanoic acid, 4-Guanidinobutyrate, 4-guanidinobutyric acid, gamma-Guanidinobutanoate, gamma-guanidinobutyrate, gamma-guanidinobutyric acid, Guanidinobutyrate, guanidobutyrate


Show all pahtways known for Show all BRENDA pathways known for 4-guanidinobutanoate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-guanidinobutyraldehyde + NAD+ + H2O = 4-guanidinobutyrate + NADH + H+
show the reaction diagram
-
4-guanidinobutanal + NAD+ = 4-guanidinobutanoate + NADH
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (7 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
guanidinobutyrate + NAD+ = nicotinamide + ?
show the reaction diagram
-
ATP + 4-guanidinebutanoic acid = ADP + N-phospho-4-guanidinobutanoic acid
show the reaction diagram
-
4-Guanidinobutyrate + H2O = 4-Aminobutyrate + urea
show the reaction diagram
-
4-Guanidinobutyrate + H2O = 4-Aminobutyrate + urea
show the reaction diagram
-
4-guanidinobutyrate + H2O = 4-aminobutanoate + urea
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (10 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-guanidinobutyraldehyde + NAD+ + H2O = 4-guanidinobutyrate + NADH + H+
show the reaction diagram
-
4-guanidinobutanal + NAD+ = 4-guanidinobutanoate + NADH
show the reaction diagram
-
4-guanidinobutyraldehyde + NAD+ + H2O = 4-guanidinobutyrate + NADH + H+
show the reaction diagram
-

Activator in Enzyme-catalyzed Reactions (1 result)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
5 mM, relative activity 109%
-

Inhibitor in Enzyme-catalyzed Reactions (6 results)

EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
slight
-
weak
-

3D Structure of Enzyme-Ligand-Complex (PDB) (1 result)

EC NUMBER
ENZYME 3D STRUCTURE

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (4 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE

KM Value (13 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE

References & Links

Links to other databases for 4-guanidinobutanoate

ChEBI
PubChem
ChEBI
PubChem