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BRENDA support

Ligand 4-aminophenol

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Basic Ligand Information

Molecular Structure
Picture of 4-aminophenol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C6H7NO
4-aminophenol
PLIKAWJENQZMHA-UHFFFAOYSA-N
Synonyms:
1-amino-4-hydroxybenzene, 4-Hydroxyaniline, p-Aminophenol, p-Hydroxyaniline
Pathway Source
Pathways
KEGG
Aminobenzoate degradation, Microbial metabolism in diverse environments
MetaCyc
4-aminophenol degradation

Roles as Enzyme Ligand

In Vivo Product in Enzyme-catalyzed Reactions (1 result)

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EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-acetamidophenol + H2O = acetate + 4-aminophenol
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (16 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
4-aminophenol + H2O2 = ?
show the reaction diagram
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4-aminophenol + H2O2 = ?
show the reaction diagram
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4-aminophenol + H2O2 = ?
show the reaction diagram
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4-aminophenol + O2 + NADPH = ?
show the reaction diagram
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4-aminophenol + O2 + NADPH = ?
show the reaction diagram
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4-aminophenol + reduced phenazine methosulfate + 2 O2 = 4-nitrophenol + phenazine methosulfate + 2 H2O
show the reaction diagram
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p-aminophenol + Fe2+ + O2 = ?
show the reaction diagram
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malonyl-CoA + 4-aminophenol = CoA + N-(phenyl)-malonamate
show the reaction diagram
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acetyl-CoA + p-aminophenol = CoA + N-acetyl-p-aminophenol
show the reaction diagram
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thiamine + 4-hydroxyaniline = 4-methyl-5-(2-hydroxyethyl)-thiazole + [(4-amino-2-methylpyrimidin-5-yl)methyl]-N-(4-hydroxyphenyl)amine
show the reaction diagram
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3'-phosphoadenylylsulfate + 4-aminophenol = adenosine 3',5'-bisphosphate + 4-aminophenyl sulfate
show the reaction diagram
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4-nitrophenyl sulfate + 4-aminophenol = 4-nitrophenol + 4-aminophenyl sulfate
show the reaction diagram
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Product in Enzyme-catalyzed Reactions (16 results)

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EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
5'-phospho-pyridoxyl-4-aminophenol + H2O + O2 = pyridoxal 5'-phosphate + 4-aminophenol + H2O2
show the reaction diagram
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4-aminophenyl phosphate + H2O = 4-aminophenol + phosphate
show the reaction diagram
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p-aminophenylphosphocholine + H2O = p-aminophenol + choline phosphate
show the reaction diagram
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p-aminophenyl-alpha-D-glucoside + H2O = alpha-D-glucose + 4-aminophenol
show the reaction diagram
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p-aminophenyl alpha-D-galactoside + H2O = p-aminophenol + D-galactose
show the reaction diagram
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benzyloxycarbonyl-Leu-Gly-Arg-4-aminophenyl ester + H2O = benzyloxycarbonyl-Leu-Gly-Arg + 4-aminophenol
show the reaction diagram
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N-(4-hydroxyphenyl)arachidonylamide + H2O = 4-aminophenol + arachidonic acid
show the reaction diagram
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Nalpha-(4-aminobenzoyl)-L-Glu + H2O = 1-amino-4-hydroxybenzene + CO2 + L-Glu
show the reaction diagram
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N-(p-tolyl)phosphoramidate + H2O = 4-aminophenol + phosphate
show the reaction diagram
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hydroxylaminobenzene = 2-aminophenol + 4-aminophenol
show the reaction diagram
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Inhibitor in Enzyme-catalyzed Reactions (7 results)

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EC NUMBER
COMMENTARY
LITERATURE
ENZYME 3D STRUCTURE
agaritine hydrolysis
-
cleavage of Tyr
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

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EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1272
-
native enzyme, at 30°C

KM Value (4 results)

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EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
2.36
-
native enzyme, at 30°C
0.00154
-
-
0.54
-
-
20
-
-

Ki Value (2 results)

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EC NUMBER
KI VALUE [MM]
KI VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
1.09
-
pH 8.0, 37°C
0.335
-
at pH 7.5 and 20°C

References & Links

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Links to other databases for 4-aminophenol

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ChEBI
PubChem
ChEBI
PubChem