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BRENDA support

Ligand 1-phenylethanol

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Basic Ligand Information

Molecular Structure
Picture of 1-phenylethanol (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C8H10O
1-phenylethanol
WAPNOHKVXSQRPX-UHFFFAOYSA-N
Synonyms:
(R,S)-1-phenylethanol, (RS)-1-phenylethanol, 1-phenethyl alcohol, 1-phenyl-1-ethanol, 1-phenylethan-1-ol, 1-phenylethyl alcohol, alpha-phenylethanol, rac-1-phenylethanol, sec-phenethyl alcohol

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
(RS)-1-phenylethanol + vinyl acetate = (R)-1-phenylethyl acetate + acetaldehyde + (S)-1-phenylethanol
show the reaction diagram
-

In Vivo Product in Enzyme-catalyzed Reactions (2 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetophenone + NADPH + H+ = 1-phenylethanol + NADP+
show the reaction diagram
-
ethylbenzene + H2O2 = 1-phenylethanol + H2O
show the reaction diagram
-

Substrate in Enzyme-catalyzed Reactions (32 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
sec-phenethyl alcohol + NADP+ = 1-phenylethanone + NADPH + H+
show the reaction diagram
-
1-phenylethanol + NAD+ = acetophenone + NADH + H+
show the reaction diagram
-
rac-1-phenylethanol + O2 = acetophenone + H2O2
show the reaction diagram
-
1-phenylethanol + H2O2 = ? + 2 H2O
show the reaction diagram
-
1-phenylethanol + H2O2 = ? + 2 H2O
show the reaction diagram
-
1-phenylethanol + H2O2 = 1-phenylethanone + H2O
show the reaction diagram
-
3'-phosphoadenylylsulfate + 1-phenylethanol = adenosine 3',5'-bisphosphate + 1-phenylethyl sulfate
show the reaction diagram
-
4-nitrophenyl sulfate + 1-phenylethanol = 4-nitrophenol + 1-phenylethyl sulfate
show the reaction diagram
-
1-phenyl-1-ethanol + vinyl acetate = ?
show the reaction diagram
-
N-Cbz-L-Tyr + 1-phenylethanol = N-Cbz-L-Tyr-1-phenylethyl ester
show the reaction diagram
-

Product in Enzyme-catalyzed Reactions (20 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
1-phenylethan-1-one + NADPH + H+ = 1-phenylethan-1-ol + NADP+
show the reaction diagram
-
1-acetophenone + NADPH = 1-phenylethanol + NADP+
show the reaction diagram
-
acetophenone + NADH + H+ = 1-phenylethan-1-ol + NAD+
show the reaction diagram
-
1-phenylethanone + NADPH + H+ = 1-phenylethanol + NADP+
show the reaction diagram
-
1-phenylethan-1-one + NADH + H+ = 1-phenylethan-1-ol + NAD+
show the reaction diagram
-
acetophenone + NADH + H+ = alpha-phenylethanol + NAD+
show the reaction diagram
-
ethylbenzene + NADH + O2 = cis-2,3-dihydroxy-1-ethyl-cyclohexa-4,6-diene + 1-phenethyl alcohol + NAD+
show the reaction diagram
-
ethylbenzene + NAD(P)H + H+ + O2 = 1-phenylethanol + 3-ethylphenol + 4-ethylphenol + NAD(P)+ + H2O
show the reaction diagram
-
ethylbenzene + [reduced NADPH-hemoprotein reductase] + O2 = 1-phenylethyl alcohol + 2-phenylethyl alcohol + [reduced NADPH-hemoprotein reductase] + O2
show the reaction diagram
-
ethylbenzene + putidaredoxin + O2 = 1-phenylethanol + oxidized putidaredoxin + H2O
show the reaction diagram
-

Enzyme Kinetic Parameters

kcat Value (Turnover Number) (2 results)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
35.7
-
pH 9.0, 70°C
35.7
-
with NAD+ as cosubstrate, at pH 6.0 and 70°C

KM Value (9 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
3
-
pH and temperature not specified in the publication
244
-
with NAD+ as cosubstrate, at pH 6.0 and 70°C

References & Links

Links to other databases for 1-phenylethanol

ChEBI
PubChem
ChEBI
PubChem