Ligand (S)-1-pyrroline-5-carboxylate

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Basic Ligand Information

Molecular Structure
Picture of (S)-1-pyrroline-5-carboxylate (click for magnification)
Molecular Formula
BRENDA Name
InChIKey
C5H7NO2
(S)-1-pyrroline-5-carboxylate
DWAKNKKXGALPNW-BYPYZUCNSA-M
Synonyms:
L-1-pyrroline-5-carboxylate, L-1-pyrroline-5-carboxylic acid, L-DELTA1-pyrroline-5-carboxylate, L-DELTA1-pyrroline 5-carboxylate, L-pyrroline-5-carboxylate


Show all pahtways known for Show all BRENDA pathways known for (S)-1-pyrroline-5-carboxylate

Roles as Enzyme Ligand

In Vivo Substrate in Enzyme-catalyzed Reactions (3 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
acetyl-CoA + L-DELTA1-pyrroline 5-carboxylate = CoA + N-acetyl-L-DELTA1-pyrroline 5-carboxylate
show the reaction diagram
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In Vivo Product in Enzyme-catalyzed Reactions (9 results)

EC NUMBER
PROVEN IN VIVO REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3 2-oxoglutarate + L-arginine + 3 O2 = 2 C2H4 + succinate + 7 CO2 + 3 H2O + guanidine + L-DELTA1-pyrroline-5-carboxylate
show the reaction diagram
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Substrate in Enzyme-catalyzed Reactions (5 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE

Product in Enzyme-catalyzed Reactions (27 results)

EC NUMBER
REACTION
REACTION DIAGRAM
LITERATURE
ENZYME 3D STRUCTURE
3 2-oxoglutarate + L-arginine + 3 O2 = 2 C2H4 + succinate + 7 CO2 + 3 H2O + guanidine + L-DELTA1-pyrroline-5-carboxylate
show the reaction diagram
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Enzyme Kinetic Parameters

kcat Value (Turnover Number) (1 result)

EC NUMBER
TURNOVER NUMBER [1/S]
TURNOVER NUMBER MAXIMUM [1/S]
COMMENTARY
LITERATURE
1.52
-
pH 7.8, 22C

KM Value (26 results)

EC NUMBER
KM VALUE [MM]
KM VALUE MAXIMUM [MM]
COMMENTARY
LITERATURE
0.0015
-
pH 7.8, 22C

References & Links

Links to other databases for (S)-1-pyrroline-5-carboxylate

ChEBI
PubChem
ChEBI
PubChem